Page last updated: 2024-10-24

celecoxib and Nausea

celecoxib has been researched along with Nausea in 8 studies

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
" There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo."6.53Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016)
"The combination of celecoxib with docetaxel and irinotecan did not ameliorate irinotecan-induced diarrhea."5.11A phase I trial of celecoxib in combination with docetaxel and irinotecan in patients with advanced cancer. ( Adjei, AA; Croghan, GC; Dy, GK; Furth, A; Hanson, LJ; Mandrekar, S; Okuno, SH; Peethambaram, PP, 2005)
"To determine the upper gastrointestinal (GI) tolerability of celecoxib, naproxen, and placebo in patients with rheumatoid arthritis (RA) and osteoarthritis (OA)."5.09Upper gastrointestinal tolerability of celecoxib, a COX-2 specific inhibitor, compared to naproxen and placebo. ( Agrawal, NM; Bensen, WG; Burke, TA; Geis, GS; Makuch, RW; Maurath, CJ; Zabinski, RA; Zhao, SZ, 2000)
"The aim of this meta-analysis was to assess the analgesic efficacy and adverse effects of celecoxib compared to non-opioid drugs after third molar surgery."2.82Analgesic effectiveness and safety of celecoxib versus non-opioid active controls after third molar surgery: A meta-analytical evaluation. ( Alonso-Castro, ÁJ; Franco-de la Torre, L; Franco-González, MA; Isiordia-Espinoza, MA, 2022)
"Celecoxib 400 mg was taken orally twice daily during chemoradiation, up to 1 week before surgery, and for 6 months following surgery."2.82Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced esophageal cancer. ( Bueno, R; Choi, N; Cleary, JM; Donahue, DM; Enzinger, PC; Fidias, PM; Fuchs, CS; Gaissert, HA; Jaklitsch, MT; Kulke, MH; Lynch, TP; Mamon, HJ; Mentzer, SJ; Meyerhardt, JA; Swanson, RS; Szymonifka, J; Wain, J, 2016)
" There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo."2.53Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Isiordia-Espinoza, MA1
Franco-González, MA1
Alonso-Castro, ÁJ1
Franco-de la Torre, L1
Xu, C1
Gu, K1
Yasen, Y1
Hou, Y1
Cleary, JM1
Mamon, HJ1
Szymonifka, J1
Bueno, R1
Choi, N1
Donahue, DM1
Fidias, PM1
Gaissert, HA1
Jaklitsch, MT1
Kulke, MH1
Lynch, TP1
Mentzer, SJ1
Meyerhardt, JA1
Swanson, RS1
Wain, J1
Fuchs, CS1
Enzinger, PC1
Goldstein, JL1
Zhao, SZ2
Burke, TA2
Palmer, R1
von Allmen, H1
Henderson, SC1
Dy, GK1
Mandrekar, S1
Peethambaram, PP1
Okuno, SH1
Croghan, GC1
Hanson, LJ1
Furth, A1
Adjei, AA1
Csiki, I1
Morrow, JD1
Sandler, A1
Shyr, Y1
Oates, J1
Williams, MK1
Dang, T1
Carbone, DP1
Johnson, DH1
Bensen, WG1
Zabinski, RA1
Makuch, RW1
Maurath, CJ1
Agrawal, NM1
Geis, GS1
Berenbaum, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Cisplatin, CPT-11, Celecoxib (PCC), Concurrent Radiation Therapy, and Surgery for Resectable Esophageal Cancer[NCT00137852]Phase 235 participants (Actual)Interventional2002-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for celecoxib and Nausea

ArticleYear
Analgesic effectiveness and safety of celecoxib versus non-opioid active controls after third molar surgery: A meta-analytical evaluation.
    Journal of stomatology, oral and maxillofacial surgery, 2022, Volume: 123, Issue:3

    Topics: Analgesics; Celecoxib; Humans; Ibuprofen; Molar, Third; Nausea; Pain, Postoperative; Vomiting

2022
Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials.
    Medicine, 2016, Volume: 95, Issue:20

    Topics: Abdominal Pain; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Diarrhea; Dyspepsia; Headache;

2016
[New nonsteroidal antiinflammatory drugs in rheumatoid arthritis].
    Annales de medecine interne, 2002, Volume: 153, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Gastric Mucosa; Humans; L

2002

Trials

4 trials available for celecoxib and Nausea

ArticleYear
Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced esophageal cancer.
    BMC cancer, 2016, 07-13, Volume: 16

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptot

2016
A phase I trial of celecoxib in combination with docetaxel and irinotecan in patients with advanced cancer.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camp

2005
Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase II trial of celecoxib and docetaxel.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inducing Agents; Antineoplastic Agents, Phytogenic; Ant

2005
Upper gastrointestinal tolerability of celecoxib, a COX-2 specific inhibitor, compared to naproxen and placebo.
    The Journal of rheumatology, 2000, Volume: 27, Issue:8

    Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxyg

2000

Other Studies

1 other study available for celecoxib and Nausea

ArticleYear
Incidence of outpatient physician claims for upper gastrointestinal symptoms among new users of celecoxib, ibuprofen, and naproxen in an insured population in the United States.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:12

    Topics: Abdominal Pain; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhi

2003