celecoxib has been researched along with Nasopharyngeal Carcinoma in 7 studies
Nasopharyngeal Carcinoma: A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, the radiation-enhancing effects of combined treatment with nimotuzumab, a humanized EGFR-blocking antibody, and celecoxib, a COX-2 selective inhibitor, in human nasopharyngeal carcinoma (NPC) cells were investigated." | 7.88 | Radiosensitivity enhancement by combined treatment of nimotuzumab and celecoxib on nasopharyngeal carcinoma cells. ( Huang, J; Liu, F; Pang, Q; Yang, B; Yu, J; Yuan, X; Zhang, F; Zhang, H; Zhou, L, 2018) |
| "To investigate the synergistic cytotoxicity of cis-dichlorodiamine platinum (DDP) and celecoxib on nasopharyngeal carcinoma TW03 cell which is resistant to DDP (TW03/DDP)." | 7.81 | [Combined application of cisplatin and celecoxib inhibits the proliferation and promotes apoptosis of nasopharyngeal carcinoma cells resistant to cisplatin]. ( Chen, J; Li, Q; Liu, S; Peng, J, 2015) |
| "The cell colony formation assay after the combination of celecoxib and radiation treatment was done on C666-1, CNE-1 and CNE-2 nasopharyngeal carcinoma cells, which expressed different COX-2 levels." | 7.80 | Celecoxib enhances radiosensitivity via induction of G₂-M phase arrest and apoptosis in nasopharyngeal carcinoma. ( Chen, WB; Huang, B; Liang, CH; Qiu, QH; Zhang, SX, 2014) |
| "To investigate the mechanisms underlying the anticancer effect of celecoxib on nasopharyngeal carcinoma (NPC)." | 7.78 | Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. ( Hu, GQ; Hu, GY; Liu, DB; Long, GX; Mei, Q; Qiu, H, 2012) |
| "Celecoxib is a selective inhibitor of COX-2, whose connection with the development and progression of human tumors has been extensively studied." | 5.40 | Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity. ( Gan, L; Hu, GQ; Hu, GY; Jiang, JZ; Li, WW; Liu, DB; Long, GX; Mei, Q; Sun, W; Wang, JF, 2014) |
| "To investigate the synergistic cytotoxicity of cis-dichlorodiamine platinum (DDP) and celecoxib on nasopharyngeal carcinoma TW03 cell which is resistant to DDP (TW03/DDP)." | 3.81 | [Combined application of cisplatin and celecoxib inhibits the proliferation and promotes apoptosis of nasopharyngeal carcinoma cells resistant to cisplatin]. ( Chen, J; Li, Q; Liu, S; Peng, J, 2015) |
| "The cell colony formation assay after the combination of celecoxib and radiation treatment was done on C666-1, CNE-1 and CNE-2 nasopharyngeal carcinoma cells, which expressed different COX-2 levels." | 3.80 | Celecoxib enhances radiosensitivity via induction of G₂-M phase arrest and apoptosis in nasopharyngeal carcinoma. ( Chen, WB; Huang, B; Liang, CH; Qiu, QH; Zhang, SX, 2014) |
| "To investigate the mechanisms underlying the anticancer effect of celecoxib on nasopharyngeal carcinoma (NPC)." | 3.78 | Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. ( Hu, GQ; Hu, GY; Liu, DB; Long, GX; Mei, Q; Qiu, H, 2012) |
| "Celecoxib combined with radiotherapy could induce apoptosis and enhance the radiosensitivity of human nasopharyngeal carcinoma CNE-2Z cell lines." | 3.77 | [Effects of celecoxib combined with radiotherapy on apoptosis of CNE-2Z cell lines]. ( Gui, P; Peng, P; Wei, LZ; Xiang, YZ; Xiong, ZJ; Yu, L, 2011) |
| "Celecoxib is a selective inhibitor of COX-2, whose connection with the development and progression of human tumors has been extensively studied." | 1.40 | Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity. ( Gan, L; Hu, GQ; Hu, GY; Jiang, JZ; Li, WW; Liu, DB; Long, GX; Mei, Q; Sun, W; Wang, JF, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, T | 1 |
| Fu, X | 1 |
| Qu, J | 1 |
| Zhang, M | 1 |
| Chen, H | 1 |
| Wang, Y | 1 |
| Wang, B | 1 |
| Li, J | 1 |
| Liu, J | 1 |
| Liu, P | 1 |
| Huang, J | 1 |
| Yuan, X | 1 |
| Pang, Q | 1 |
| Zhang, H | 1 |
| Yu, J | 1 |
| Yang, B | 1 |
| Zhou, L | 1 |
| Zhang, F | 1 |
| Liu, F | 1 |
| Li, WW | 1 |
| Long, GX | 2 |
| Liu, DB | 2 |
| Mei, Q | 2 |
| Wang, JF | 1 |
| Hu, GY | 2 |
| Jiang, JZ | 1 |
| Sun, W | 1 |
| Gan, L | 1 |
| Hu, GQ | 2 |
| Zhang, SX | 1 |
| Qiu, QH | 1 |
| Chen, WB | 1 |
| Liang, CH | 1 |
| Huang, B | 1 |
| Chen, J | 1 |
| Liu, S | 1 |
| Li, Q | 1 |
| Peng, J | 1 |
| Xiang, YZ | 1 |
| Wei, LZ | 1 |
| Yu, L | 1 |
| Gui, P | 1 |
| Peng, P | 1 |
| Xiong, ZJ | 1 |
| Qiu, H | 1 |
7 other studies available for celecoxib and Nasopharyngeal Carcinoma
| Article | Year |
|---|---|
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Topics: Animals; Apoptosis; Autophagy; Celecoxib; Cell Line, Tumor; Cell Proliferation; Humans; JNK Mitogen- | 2021 |
Radiosensitivity enhancement by combined treatment of nimotuzumab and celecoxib on nasopharyngeal carcinoma cells.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cell P | 2018 |
Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity.
Topics: Carcinoma; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coloring Agents; Cyclooxy | 2014 |
Celecoxib enhances radiosensitivity via induction of G₂-M phase arrest and apoptosis in nasopharyngeal carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Celecoxib; Cell Cycle Checkpoints; Cell Division; Cell | 2014 |
[Combined application of cisplatin and celecoxib inhibits the proliferation and promotes apoptosis of nasopharyngeal carcinoma cells resistant to cisplatin].
Topics: Antineoplastic Agents; Carcinoma; Celecoxib; Cell Proliferation; Cisplatin; Drug Resistance, Neoplas | 2015 |
[Effects of celecoxib combined with radiotherapy on apoptosis of CNE-2Z cell lines].
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma; Caspase 3; Celecoxib; Cell Line, Tumor; Humans; Na | 2011 |
Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma; Celecoxib; Cell Cycle Checkpoints; C | 2012 |