Page last updated: 2024-10-24
celecoxib and Mucositis, Oral
celecoxib has been researched along with Mucositis, Oral in 2 studies
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|
| Lalla, RV | 1 |
| Choquette, LE | 1 |
| Curley, KF | 1 |
| Dowsett, RJ | 1 |
| Feinn, RS | 1 |
| Hegde, UP | 1 |
| Pilbeam, CC | 1 |
| Salner, AL | 1 |
| Sonis, ST | 1 |
| Peterson, DE | 1 |
| Haagen, J | 1 |
| Krohn, H | 1 |
| Röllig, S | 1 |
| Schmidt, M | 1 |
| Wolfram, K | 1 |
| Dörr, W | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| Cyclooxygenase-2 Inhibition in Radiation-Induced Oral Mucositis[NCT00698204] | Phase 2 | 43 participants (Actual) | Interventional | 2003-07-31 | Completed |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trial Outcomes
Clinical Oral Mucosal Injury Score at Cumulative Radiation Dose of 5000 cGy
"Oral Mucositis Assessment Scale (OMAS) was used to assess oral mucosal injury during the period of radiation therapy. This validated scale scores ulceration and erythema independently at nine specified sites in the oral cavity. Ulceration is scored from 0-3 based on size of lesion and erythema is scored from 0-2 based on severity of erythema. The sum of scores is then divided by 9.~The mean OMAS score at a cumulative radiation dose of 5000 cGy (approximately 5 weeks of treatment) was compared between groups." (NCT00698204)
Timeframe: 5 weeks from start of radiation therapy (5000 cGy)
| Intervention | units on a scale (Mean) |
|---|
| I- Celecoxib | 1.42 |
| II- Placebo | 1.36 |
Evaluation of Pain Severity at 5000 cGy Radiation
Mean worst pain at 5000 cGy on 0-10 scale, 0 = no pain, 10 = worst pain imaginable (NCT00698204)
Timeframe: 5 weeks from start of radiation therapy (cumulative dose of 5000 cGy)
| Intervention | units on a scale (Mean) |
|---|
| I- Celecoxib | 4.47 |
| II- Placebo | 3.70 |
Trials
1 trial available for celecoxib and Mucositis, Oral
Other Studies
1 other study available for celecoxib and Mucositis, Oral