Page last updated: 2024-10-24

celecoxib and Metaplasia

celecoxib has been researched along with Metaplasia in 6 studies

Metaplasia: A condition in which there is a change of one adult cell type to another similar adult cell type.

Research Excerpts

ExcerptRelevanceReference
"To test whether the chronic users of celecoxib, a selective cyclo-oxygenase-2 inhibitor, had less Helicobacter pylori-related intestinal metaplasia or if such users' intestinal metaplasia could be prone to disappear after H."7.74Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication. ( Cheng, HC; Hung, KH; Liou, MF; Sheu, BS; Wu, JJ; Yang, HB, 2007)
"To test whether the chronic users of celecoxib, a selective cyclo-oxygenase-2 inhibitor, had less Helicobacter pylori-related intestinal metaplasia or if such users' intestinal metaplasia could be prone to disappear after H."3.74Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication. ( Cheng, HC; Hung, KH; Liou, MF; Sheu, BS; Wu, JJ; Yang, HB, 2007)
"A series of 90 rats underwent a duodenoesophageal reflux surgery were divided into 2 groups: the control group was given a commercial chow and the celecoxib group experimental chow containing celecoxib."3.73[A COX-2 inhibitor suppresses esophageal inflammation-metaplasia-adenocarcinoma sequence in rats]. ( Fujimura, T; Miwa, K; Oyama, K, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colby, JK1
Klein, RD1
McArthur, MJ1
Conti, CJ1
Kiguchi, K1
Kawamoto, T1
Riggs, PK1
Pavone, AI1
Sawicki, J1
Fischer, SM1
Hung, KH2
Yang, HB3
Cheng, HC3
Wu, JJ2
Sheu, BS3
Tsai, YC1
Wu, CT1
Chang, WL1
Miwa, K1
Oyama, K1
Fujimura, T1
Liou, MF1
Futagami, S1
Suzuki, K1
Hiratsuka, T1
Shindo, T1
Hamamoto, T1
Ueki, N1
Kusunoki, M1
Miyake, K1
Gudis, K1
Tsukui, T1
Sakamoto, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on the Probiotics Regulating miRNA in H. Pylori-induced Wnt/β-catenin Gastric Carcinogenesis.[NCT05544396]100 participants (Anticipated)Interventional2023-11-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for celecoxib and Metaplasia

ArticleYear
Chemopreventive effect of celecoxib in gastric cancer.
    Inflammopharmacology, 2007, Volume: 15, Issue:1

    Topics: Animals; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gastric

2007

Trials

2 trials available for celecoxib and Metaplasia

ArticleYear
Short-term celecoxib to regress long-term persistent gastric intestinal metaplasia after Helicobacter pylori eradication.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:1

    Topics: Aged; Atrophy; beta Catenin; Biomarkers; Blood Urea Nitrogen; Celecoxib; Creatinine; Cyclooxygenase

2010
Long-term celecoxib can prevent the progression of persistent gastric intestinal metaplasia After H. pylori eradication.
    Helicobacter, 2013, Volume: 18, Issue:2

    Topics: Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Gastritis, Atrophic; Helicobacter Infections;

2013

Other Studies

3 other studies available for celecoxib and Metaplasia

ArticleYear
Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:8

    Topics: Animals; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Celecoxib; Cell Transformation, Neoplastic

2008
[A COX-2 inhibitor suppresses esophageal inflammation-metaplasia-adenocarcinoma sequence in rats].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:8

    Topics: Adenocarcinoma; Animals; Apoptosis; Barrett Esophagus; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2

2005
Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 2007, Feb-15, Volume: 25, Issue:4

    Topics: Celecoxib; Cyclooxygenase Inhibitors; Dyspepsia; Female; Gastric Mucosa; Helicobacter Infections; He

2007