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celecoxib and Infarction, Middle Cerebral Artery

celecoxib has been researched along with Infarction, Middle Cerebral Artery in 2 studies

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
"Celecoxib treatment decreased polyubiquitinated protein load and ER stress marker expression such as glucose-related protein 78 (GRP78), C/EBP (CCAAT/enhancer-binding protein) homologous protein (CHOP), and caspase 12 after 48 h of reperfusion."1.62Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome. ( Anuncibay-Soto, B; Fernández-López, A; Font-Belmonte, E; González-Rodríguez, P; Pérez-Rodríguez, D; Santos-Galdiano, M; Ugidos, IF, 2021)
"Celecoxib treatment improved the neurologic deficit, reduced the infarct volume by 50% after 48 hours of reperfusion, and resulted in a reduced percentage of SNL areas and microglia and astroglia reactivity after 48 hours of reperfusion."1.48Celecoxib Treatment Improves Neurologic Deficit and Reduces Selective Neuronal Loss and Glial Response in Rats after Transient Middle Cerebral Artery Occlusion. ( Anuncibay-Soto, B; Fernández-López, A; Font-Belmonte, E; Pérez-García, CC; Pérez-Rodríguez, D; Santos-Galdiano, M; Ugidos, IF, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Santos-Galdiano, M2
González-Rodríguez, P1
Font-Belmonte, E2
Ugidos, IF2
Anuncibay-Soto, B2
Pérez-Rodríguez, D2
Fernández-López, A2
Pérez-García, CC1

Other Studies

2 other studies available for celecoxib and Infarction, Middle Cerebral Artery

ArticleYear
Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome.
    Molecular neurobiology, 2021, Volume: 58, Issue:4

    Topics: Animals; Apoptosis; Autophagy; Biomarkers; Brain Ischemia; Celecoxib; Disease Models, Animal; eIF-2

2021
Celecoxib Treatment Improves Neurologic Deficit and Reduces Selective Neuronal Loss and Glial Response in Rats after Transient Middle Cerebral Artery Occlusion.
    The Journal of pharmacology and experimental therapeutics, 2018, Volume: 367, Issue:3

    Topics: Animals; Astrocytes; Celecoxib; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Ne

2018