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celecoxib and Granulocytic Leukemia, Chronic

celecoxib has been researched along with Granulocytic Leukemia, Chronic in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Celecoxib was tested in combination with imatinib, demonstrating that celecoxib could strengthen the cytotoxicity of imatinib in imatinib-resistant CML cells."1.43Celecoxib suppresses autophagy and enhances cytotoxicity of imatinib in imatinib-resistant chronic myeloid leukemia cells. ( Deng, XB; Fang, ZG; Lin, DJ; Liu, LL; Liu, Q; Liu, SS; Long, ZJ; Lu, Y; Zou, Y, 2016)
"Treatment with celecoxib also restored GSK3β function and led to down-regulation of β-catenin activity through transcriptional and post-translational mechanisms, two effects likely to contribute to Ph+ cell growth suppression by celecoxib."1.43Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2. ( Calabretta, B; Canonico, PL; Condorelli, F; De Dominici, M; Genazzani, AA; Gnemmi, I; Mariani, SA; Minassi, A; Minieri, V; Riva, B; Salomoni, P, 2016)
" Therefore, we examined the effect of rapamycin combined with celecoxib on K562 cells in vitro."1.40Rapamycin combined with celecoxib enhanced antitumor effects of mono treatment on chronic myelogenous leukemia cells through downregulating mTOR pathway. ( Hao, H; Li, J; Li, R; Luo, J; Xue, L, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, J1
Xue, L1
Hao, H1
Li, R1
Luo, J1
Lu, Y1
Liu, LL1
Liu, SS1
Fang, ZG1
Zou, Y1
Deng, XB1
Long, ZJ1
Liu, Q1
Lin, DJ1
Riva, B1
De Dominici, M1
Gnemmi, I1
Mariani, SA1
Minassi, A1
Minieri, V1
Salomoni, P1
Canonico, PL1
Genazzani, AA1
Calabretta, B1
Condorelli, F1
Subhashini, J1
Mahipal, SV1
Reddanna, P1
Zhang, GS1
Liu, DS1
Dai, CW1
Li, RJ1

Other Studies

5 other studies available for celecoxib and Granulocytic Leukemia, Chronic

ArticleYear
Rapamycin combined with celecoxib enhanced antitumor effects of mono treatment on chronic myelogenous leukemia cells through downregulating mTOR pathway.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Celecoxib; Cell Cycle Checkpoints; Cell L

2014
Celecoxib suppresses autophagy and enhances cytotoxicity of imatinib in imatinib-resistant chronic myeloid leukemia cells.
    Journal of translational medicine, 2016, 09-20, Volume: 14

    Topics: Adult; Apoptosis; Autophagy; Celecoxib; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; G1 Phas

2016
Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols

2016
Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro.
    Cancer letters, 2005, Jun-16, Volume: 224, Issue:1

    Topics: Apoptosis; Celecoxib; Cell Proliferation; Cyclooxygenase Inhibitors; DNA Damage; Down-Regulation; Fo

2005
Antitumor effects of celecoxib on K562 leukemia cells are mediated by cell-cycle arrest, caspase-3 activation, and downregulation of Cox-2 expression and are synergistic with hydroxyurea or imatinib.
    American journal of hematology, 2006, Volume: 81, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Bone M

2006