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celecoxib and Epithelial Ovarian Cancer

celecoxib has been researched along with Epithelial Ovarian Cancer in 6 studies

Research Excerpts

ExcerptRelevanceReference
"The purpose of our study was to investigate the therapeutic potential of Celecoxib for epithelial ovarian cancer, especially on cellular morphological changes, proliferation invasion and epithelial-mesenchymal transition (EMT)."7.81Celecoxib induces epithelial-mesenchymal transition in epithelial ovarian cancer cells via regulating ZEB1 expression. ( Li, C; Liu, P; Liu, R; Pang, Y; Xu, X; Zheng, J; Zheng, Q, 2015)
"Celecoxib was to be continued after DC termination up to 3 years."6.77A randomized phase II study investigating the addition of the specific COX-2 inhibitor celecoxib to docetaxel plus carboplatin as first-line chemotherapy for stage IC to IV epithelial ovarian cancer, Fallopian tube or primary peritoneal carcinomas: the Do ( de Graaf, H; de Munck, L; Erdkamp, FLG; Hoekman, K; Hollema, H; Lalisang, RI; Polee, M; Reyners, AKL; Schaapveld, M; Smit, WM; van Vugt, MATM; Willemse, PHB; Wymenga, ANM, 2012)
"However, the role of COX-2 in epithelial ovarian cancer (EOC), and its mechanistic details, remain poorly understood."5.48COX-2 inhibition by celecoxib in epithelial ovarian cancer attenuates E-cadherin suppression through reduced Snail nuclear translocation. ( Li, CH; Li, XW; Wang, QY; Wang, YP, 2018)
"The purpose of our study was to investigate the therapeutic potential of Celecoxib for epithelial ovarian cancer, especially on cellular morphological changes, proliferation invasion and epithelial-mesenchymal transition (EMT)."3.81Celecoxib induces epithelial-mesenchymal transition in epithelial ovarian cancer cells via regulating ZEB1 expression. ( Li, C; Liu, P; Liu, R; Pang, Y; Xu, X; Zheng, J; Zheng, Q, 2015)
"Celecoxib was to be continued after DC termination up to 3 years."2.77A randomized phase II study investigating the addition of the specific COX-2 inhibitor celecoxib to docetaxel plus carboplatin as first-line chemotherapy for stage IC to IV epithelial ovarian cancer, Fallopian tube or primary peritoneal carcinomas: the Do ( de Graaf, H; de Munck, L; Erdkamp, FLG; Hoekman, K; Hollema, H; Lalisang, RI; Polee, M; Reyners, AKL; Schaapveld, M; Smit, WM; van Vugt, MATM; Willemse, PHB; Wymenga, ANM, 2012)
"Advanced epithelial ovarian cancer (EOC) is associated with dismal outcome and progression-free survival (PFS) shortens with each subsequent relapse."1.51Oral metronomic chemotherapy for recurrent & refractory epithelial ovarian cancer: A retrospective analysis. ( Bhatla, N; Khurana, S; Kumar, L; Kumar, S; Malik, PS; Ray, MD; Sharma, A, 2019)
"However, the role of COX-2 in epithelial ovarian cancer (EOC), and its mechanistic details, remain poorly understood."1.48COX-2 inhibition by celecoxib in epithelial ovarian cancer attenuates E-cadherin suppression through reduced Snail nuclear translocation. ( Li, CH; Li, XW; Wang, QY; Wang, YP, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, A1
Malik, PS1
Khurana, S1
Kumar, S1
Bhatla, N1
Ray, MD1
Kumar, L1
Wang, YP1
Wang, QY1
Li, CH1
Li, XW1
Gupta, R1
Cristea, M1
Frankel, P1
Ruel, C1
Chen, C1
Wang, Y1
Morgan, R1
Leong, L1
Chow, W1
Koczywas, M1
Koehler, S1
Lim, D1
Luu, T1
Martel, C1
McNamara, M1
Somlo, G1
Twardowski, P1
Yen, Y1
Idorenyi, A1
Raechelle, T1
Carroll, M1
Chung, V1
Liu, R1
Zheng, J1
Li, C1
Pang, Y1
Zheng, Q1
Xu, X1
Liu, P1
van Kruchten, M1
van der Marel, P1
de Munck, L2
Hollema, H2
Arts, H1
Timmer-Bosscha, H1
de Vries, E1
Hospers, G1
Reyners, A1
Reyners, AKL1
Erdkamp, FLG1
Smit, WM1
Hoekman, K1
Lalisang, RI1
de Graaf, H1
Wymenga, ANM1
Polee, M1
van Vugt, MATM1
Schaapveld, M1
Willemse, PHB1

Trials

3 trials available for celecoxib and Epithelial Ovarian Cancer

ArticleYear
Randomized trial of oral cyclophosphamide versus oral cyclophosphamide with celecoxib for recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer.
    Cancer treatment and research communications, 2019, Volume: 21

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents

2019
Hormone receptors as a marker of poor survival in epithelial ovarian cancer.
    Gynecologic oncology, 2015, Volume: 138, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino

2015
A randomized phase II study investigating the addition of the specific COX-2 inhibitor celecoxib to docetaxel plus carboplatin as first-line chemotherapy for stage IC to IV epithelial ovarian cancer, Fallopian tube or primary peritoneal carcinomas: the Do
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino

2012

Other Studies

3 other studies available for celecoxib and Epithelial Ovarian Cancer

ArticleYear
Oral metronomic chemotherapy for recurrent & refractory epithelial ovarian cancer: A retrospective analysis.
    The Indian journal of medical research, 2019, Volume: 150, Issue:6

    Topics: Administration, Metronomic; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Com

2019
COX-2 inhibition by celecoxib in epithelial ovarian cancer attenuates E-cadherin suppression through reduced Snail nuclear translocation.
    Chemico-biological interactions, 2018, Aug-25, Volume: 292

    Topics: Blotting, Western; Cadherins; Carcinoma, Ovarian Epithelial; Celecoxib; Cell Line, Tumor; Cyclooxyge

2018
Celecoxib induces epithelial-mesenchymal transition in epithelial ovarian cancer cells via regulating ZEB1 expression.
    Archives of gynecology and obstetrics, 2015, Volume: 291, Issue:6

    Topics: Cadherins; Carcinoma, Ovarian Epithelial; Celecoxib; Cell Line, Tumor; Cell Proliferation; Down-Regu

2015