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celecoxib and Dyspepsia

celecoxib has been researched along with Dyspepsia in 12 studies

Dyspepsia: Impaired digestion, especially after eating.

Research Excerpts

ExcerptRelevanceReference
"To compare celecoxib (800 mg/day, n=1997) with diclofenac (150 mg/day, n=1996) on dyspepsia-related tolerability."9.10Dyspepsia tolerability from the patients' perspective: a comparison of celecoxib with diclofenac. ( Burke, TA; Eisen, GM; Geis, GS; Goldstein, JL; Lefkowith, J; Peña, BM, 2002)
"To test whether the chronic users of celecoxib, a selective cyclo-oxygenase-2 inhibitor, had less Helicobacter pylori-related intestinal metaplasia or if such users' intestinal metaplasia could be prone to disappear after H."7.74Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication. ( Cheng, HC; Hung, KH; Liou, MF; Sheu, BS; Wu, JJ; Yang, HB, 2007)
" There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo."6.53Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016)
"Celecoxib was as effective as lansoprazole co-therapy in the prevention of recurrences of ulcer complications in subjects with a history of NSAID-related complicated peptic ulcers."5.11Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications. ( Chan, AO; Chu, KM; Hu, WH; Hui, WM; Lai, KC; Lam, SK; Wong, BC; Wong, J; Wong, WM, 2005)
"To compare celecoxib (800 mg/day, n=1997) with diclofenac (150 mg/day, n=1996) on dyspepsia-related tolerability."5.10Dyspepsia tolerability from the patients' perspective: a comparison of celecoxib with diclofenac. ( Burke, TA; Eisen, GM; Geis, GS; Goldstein, JL; Lefkowith, J; Peña, BM, 2002)
"To determine the upper gastrointestinal (GI) tolerability of celecoxib, naproxen, and placebo in patients with rheumatoid arthritis (RA) and osteoarthritis (OA)."5.09Upper gastrointestinal tolerability of celecoxib, a COX-2 specific inhibitor, compared to naproxen and placebo. ( Agrawal, NM; Bensen, WG; Burke, TA; Geis, GS; Makuch, RW; Maurath, CJ; Zabinski, RA; Zhao, SZ, 2000)
"Ursodeoxycholic acid has a limited therapeutic role in functional dyspepsia."4.31Potential therapeutic benefit of ursodeoxycholic acid in the management of non hepato-biliary upper gastrointestinal disorders. ( Khayyat, YM, 2023)
"To test whether the chronic users of celecoxib, a selective cyclo-oxygenase-2 inhibitor, had less Helicobacter pylori-related intestinal metaplasia or if such users' intestinal metaplasia could be prone to disappear after H."3.74Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication. ( Cheng, HC; Hung, KH; Liou, MF; Sheu, BS; Wu, JJ; Yang, HB, 2007)
" There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo."2.53Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (58.33)29.6817
2010's3 (25.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Khayyat, YM1
Lee, S1
Kim, JG1
Kim, HJ1
Xu, C1
Gu, K1
Yasen, Y1
Hou, Y1
Raynauld, JP1
Martel-Pelletier, J1
Beaulieu, A1
Bessette, L1
Morin, F1
Choquette, D1
Haraoui, B1
Abram, F1
Pelletier, JP1
Cryer, BL1
Sostek, MB1
Fort, JG1
Svensson, O1
Hwang, C1
Hochberg, MC1
van der Bijl, P2
Goldstein, JL2
Zhao, SZ2
Burke, TA3
Palmer, R1
von Allmen, H1
Henderson, SC1
Chan, FK1
Hung, LC1
Suen, BY1
Wong, VW1
Hui, AJ1
Wu, JC1
Leung, WK1
Lee, YT1
To, KF1
Chung, SC1
Sung, JJ1
Lai, KC1
Chu, KM1
Hui, WM1
Wong, BC1
Hu, WH1
Wong, WM1
Chan, AO1
Wong, J1
Lam, SK1
Yang, HB1
Cheng, HC1
Sheu, BS1
Hung, KH1
Liou, MF1
Wu, JJ1
Bensen, WG1
Zabinski, RA1
Makuch, RW1
Maurath, CJ1
Agrawal, NM1
Geis, GS2
Eisen, GM1
Peña, BM1
Lefkowith, J1

Reviews

2 reviews available for celecoxib and Dyspepsia

ArticleYear
Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials.
    Medicine, 2016, Volume: 95, Issue:20

    Topics: Abdominal Pain; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Diarrhea; Dyspepsia; Headache;

2016
Non-steroidal anti-inflammatory drugs in orofacial pain management--an update.
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2002, Volume: 57, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Drug Interactions; Dy

2002

Trials

6 trials available for celecoxib and Dyspepsia

ArticleYear
Efficacy of Aceclofenac and Ilaprazole Combination Therapy versus Celecoxib Monotherapy for Treating NSAID-Induced Dyspepsia in Lumbar Spinal Stenosis Patients.
    Medicina (Kaunas, Lithuania), 2023, Jul-14, Volume: 59, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Double-Blind Method; Dyspepsia; Humans; Prospect

2023
A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two randomized, parallel-group, placebo-controlled trials.
    Annals of medicine, 2011, Volume: 43, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cycl

2011
Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: results of a randomized double-blind trial.
    Gastroenterology, 2004, Volume: 127, Issue:4

    Topics: Adult; Aged; Arthritis; Celecoxib; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Dyspe

2004
Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications.
    The American journal of medicine, 2005, Volume: 118, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-

2005
Upper gastrointestinal tolerability of celecoxib, a COX-2 specific inhibitor, compared to naproxen and placebo.
    The Journal of rheumatology, 2000, Volume: 27, Issue:8

    Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxyg

2000
Dyspepsia tolerability from the patients' perspective: a comparison of celecoxib with diclofenac.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Diclofenac; Double-Blind

2002

Other Studies

4 other studies available for celecoxib and Dyspepsia

ArticleYear
Potential therapeutic benefit of ursodeoxycholic acid in the management of non hepato-biliary upper gastrointestinal disorders.
    Saudi medical journal, 2023, Volume: 44, Issue:5

    Topics: Adenomatous Polyposis Coli; Adult; Celecoxib; Drug Therapy, Combination; Dyspepsia; Humans; Ursodeox

2023
An open-label pilot study evaluating by magnetic resonance imaging the potential for a disease-modifying effect of celecoxib compared to a modelized historical control cohort in the treatment of knee osteoarthritis.
    Seminars in arthritis and rheumatism, 2010, Volume: 40, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Celecoxib; Cohort Studies; Cycl

2010
Incidence of outpatient physician claims for upper gastrointestinal symptoms among new users of celecoxib, ibuprofen, and naproxen in an insured population in the United States.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:12

    Topics: Abdominal Pain; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhi

2003
Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 2007, Feb-15, Volume: 25, Issue:4

    Topics: Celecoxib; Cyclooxygenase Inhibitors; Dyspepsia; Female; Gastric Mucosa; Helicobacter Infections; He

2007