celecoxib has been researched along with Duodenal Ulcer in 12 studies
Duodenal Ulcer: A PEPTIC ULCER located in the DUODENUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A lower incidence of gastric and duodenal ulcers was seen in celecoxib/aspirin-treated subjects (19%) vs." | 9.12 | The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor. ( Dodge, WE; Goldstein, JL; Lanza, FL; Lowry, SC; Schwartz, HI, 2006) |
| " We describe a 67-year-old man taking a higher than usual dose of celecoxib (Celebrex) for osteoarthritis with resultant gastric erosions, ulceration, and a significant gastrointestinal (GI) hemorrhage." | 7.71 | Celecoxib-induced upper gastrointestinal hemorrhage and ulceration. ( Crawford, AS; White, JG, 2002) |
| "To determine the rate of endoscopic gastric/duodenal ulcers (GDUs) associated with use of aspirin (81 mg q." | 5.13 | Endoscopic ulcer rates in healthy subjects associated with use of aspirin (81 mg q.d.) alone or coadministered with celecoxib or naproxen: a randomized, 1-week trial. ( Aisenberg, J; Berger, MF; Dodge, WE; Goldstein, JL; Zakko, SF, 2008) |
| "A lower incidence of gastric and duodenal ulcers was seen in celecoxib/aspirin-treated subjects (19%) vs." | 5.12 | The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor. ( Dodge, WE; Goldstein, JL; Lanza, FL; Lowry, SC; Schwartz, HI, 2006) |
| "Subjects 18 years or older with osteoarthritis, without gastroduodenal ulcer or erosive esophagitis at baseline endoscopy, and a cardiovascular indication for prophylaxis low-dose (81 or 325 mg) aspirin were prescribed open-label aspirin and blindly randomized to celecoxib 200 mg/day or naproxen 500 mg twice daily plus lansoprazole 30 mg once daily." | 5.12 | Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial. ( Amer, F; Cryer, B; Goldstein, JL; Hunt, B, 2007) |
| " We describe a 67-year-old man taking a higher than usual dose of celecoxib (Celebrex) for osteoarthritis with resultant gastric erosions, ulceration, and a significant gastrointestinal (GI) hemorrhage." | 3.71 | Celecoxib-induced upper gastrointestinal hemorrhage and ulceration. ( Crawford, AS; White, JG, 2002) |
| "The aim of this study was to predict the cost effectiveness of celecoxib, a cyclo-oxygenase 2 (COX-2) specific inhibitor, in the treatment of arthritis patients in Switzerland." | 3.71 | Economic evaluation of celecoxib, a new cyclo-oxygenase 2 specific inhibitor, in Switzerland. ( Chancellor, JV; de Cruz, E; Hunsche, E; Sarasin, FP, 2001) |
| "The treatment of 20 osteoarthrosis patients was carried out with the help of Celecoxib while 18 patients were on Tramadol as an analgesic therapy against a standard antiulcer therapy." | 2.71 | [Celecoxib and Tramadol as an alternative osteoarthrosis therapy in patients with NSAID gastropathy]. ( Drozdov, VN; Kolomiets, EV; Lazebnik, LB; Li, IA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (83.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanbayashi, Y | 1 |
| Konishi, H | 1 |
| Maehata, Y | 1 |
| Esaki, M | 1 |
| Morishita, T | 1 |
| Kochi, S | 1 |
| Endo, S | 1 |
| Shikata, K | 1 |
| Kobayashi, H | 1 |
| Matsumoto, T | 1 |
| Chan, FK | 1 |
| Hung, LC | 1 |
| Suen, BY | 1 |
| Wu, JC | 1 |
| Lee, KC | 1 |
| Leung, VK | 1 |
| Hui, AJ | 1 |
| To, KF | 1 |
| Leung, WK | 1 |
| Wong, VW | 1 |
| Chung, SC | 1 |
| Sung, JJ | 1 |
| Crawford, AS | 1 |
| White, JG | 1 |
| Lazebnik, LB | 1 |
| Drozdov, VN | 1 |
| Li, IA | 1 |
| Kolomiets, EV | 1 |
| Goldstein, JL | 4 |
| Lowry, SC | 1 |
| Lanza, FL | 1 |
| Schwartz, HI | 1 |
| Dodge, WE | 2 |
| Aisenberg, J | 1 |
| Zakko, SF | 1 |
| Berger, MF | 1 |
| Cryer, B | 1 |
| Amer, F | 1 |
| Hunt, B | 1 |
| Noble, SL | 1 |
| King, DS | 1 |
| Olutade, JI | 1 |
| Burke, TA | 1 |
| Zabinski, RA | 1 |
| Pettitt, D | 1 |
| Maniadakis, N | 1 |
| Maurath, CJ | 1 |
| Chancellor, JV | 1 |
| Hunsche, E | 1 |
| de Cruz, E | 1 |
| Sarasin, FP | 1 |
| Bannwarth, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Acetaminophen Potentiate the Gastroduodenal Mucosal Injury of Aspirin? A Prospective, Randomized, Pilot Study.[NCT00594867] | Phase 4 | 94 participants (Actual) | Interventional | 2006-12-31 | Completed | ||
| A Randomized, Double-Blind, Phase 3 Study to Compare the Efficacy and Safety of Lansoprazole 30 mg QD and Naproxen 500 mg BID Versus Celecoxib 200 mg QD in Risk Reduction of Non Steroidal Anti-Inflammatory-Associated Ulcers in Osteoarthritis Subjects Taki[NCT00175032] | Phase 3 | 1,045 participants (Actual) | Interventional | 2003-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for celecoxib and Duodenal Ulcer
| Article | Year |
|---|---|
Cyclooxygenase-2 enzyme inhibitors: place in therapy.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bleeding Time; Blood P | 2000 |
A framework for evaluating the clinical consequences of initial therapy with NSAIDs, NSAIDs plus gastroprotective agents, or celecoxib in the treatment of arthritis.
Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Clinical T | 2001 |
[COX-2 specific inhibitors: are NSAIDs and the stomach become reconcilied?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C | 2001 |
6 trials available for celecoxib and Duodenal Ulcer
| Article | Year |
|---|---|
Small bowel injury induced by selective cyclooxygenase-2 inhibitors: a prospective, double-blind, randomized clinical trial comparing celecoxib and meloxicam.
Topics: Adult; Capsule Endoscopes; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Duodenal Ulc | 2012 |
Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Cyclooxygenase 2; | 2002 |
[Celecoxib and Tramadol as an alternative osteoarthrosis therapy in patients with NSAID gastropathy].
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; D | 2004 |
The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Doub | 2006 |
Endoscopic ulcer rates in healthy subjects associated with use of aspirin (81 mg q.d.) alone or coadministered with celecoxib or naproxen: a randomized, 1-week trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Double-Blind Method; Drug Therapy | 2008 |
Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovas | 2007 |
3 other studies available for celecoxib and Duodenal Ulcer
| Article | Year |
|---|---|
Predictive Factors for NSAIDs-related Gastrointestinal Toxicity: Can COX-2 Selective Inhibtor Prevent it?.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antineoplast | 2015 |
Celecoxib-induced upper gastrointestinal hemorrhage and ulceration.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Duodenal Ulcer; | 2002 |
Economic evaluation of celecoxib, a new cyclo-oxygenase 2 specific inhibitor, in Switzerland.
Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Clinical T | 2001 |