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celecoxib and Diabetic Retinopathy

celecoxib has been researched along with Diabetic Retinopathy in 7 studies

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"In this prospective, factorial, randomized, multicenter trial, we compared cyclo-oxygenase-2 inhibitor (celecoxib) with placebo and diode grid laser with standard Early Treatment Diabetic Retinopathy Study focal laser treatment in 86 participants with diabetic macular edema."9.14Preliminary assessment of celecoxib and microdiode pulse laser treatment of diabetic macular edema. ( Aiello, LP; Avery, R; Callanan, D; Chew, EY; Coleman, HR; Ferris, FL; Figueroa, M; Fish, G; Haller, JA; Hammel, K; Ip, M; Kim, J; Martin, D; Thompson, DJ, 2010)
"In this prospective, factorial, randomized, multicenter trial, we compared cyclo-oxygenase-2 inhibitor (celecoxib) with placebo and diode grid laser with standard Early Treatment Diabetic Retinopathy Study focal laser treatment in 86 participants with diabetic macular edema."5.14Preliminary assessment of celecoxib and microdiode pulse laser treatment of diabetic macular edema. ( Aiello, LP; Avery, R; Callanan, D; Chew, EY; Coleman, HR; Ferris, FL; Figueroa, M; Fish, G; Haller, JA; Hammel, K; Ip, M; Kim, J; Martin, D; Thompson, DJ, 2010)
"The present investigation is aimed at improving the ocular bioavailability of a poorly water soluble drug, celecoxib, to offer new options in the treatment of chronic eye diseases, such as age-related macular degeneration and diabetic retinopathy."3.79Synthesis, characterization and in vitro studies of celecoxib-loaded poly(ortho ester) nanoparticles targeted for intraocular drug delivery. ( Jablonski, MM; Palamoor, M, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Palamoor, M1
Jablonski, MM1
Cheruvu, NP2
Amrite, AC3
Kompella, UB3
Chew, EY1
Kim, J1
Coleman, HR1
Aiello, LP1
Fish, G1
Ip, M1
Haller, JA1
Figueroa, M1
Martin, D1
Callanan, D1
Avery, R1
Hammel, K1
Thompson, DJ1
Ferris, FL1
Amrite, A1
Pugazhenthi, V1
Cheruvu, N1
Kompella, U1
Ayalasomayajula, SP2
Berkowitz, BA1
Roberts, R1
Luan, H1
Peysakhov, J1
Knoerzer, DL1
Connor, JR1
Hohman, TC1

Reviews

1 review available for celecoxib and Diabetic Retinopathy

ArticleYear
Delivery of celecoxib for treating diseases of the eye: influence of pigment and diabetes.
    Expert opinion on drug delivery, 2010, Volume: 7, Issue:5

    Topics: Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Diabetic Retinopathy; Drug Delivery Systems; Humans

2010

Trials

1 trial available for celecoxib and Diabetic Retinopathy

ArticleYear
Preliminary assessment of celecoxib and microdiode pulse laser treatment of diabetic macular edema.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:3

    Topics: Administration, Oral; Capillary Permeability; Celecoxib; Combined Modality Therapy; Cyclooxygenase 2

2010

Other Studies

5 other studies available for celecoxib and Diabetic Retinopathy

ArticleYear
Synthesis, characterization and in vitro studies of celecoxib-loaded poly(ortho ester) nanoparticles targeted for intraocular drug delivery.
    Colloids and surfaces. B, Biointerfaces, 2013, Dec-01, Volume: 112

    Topics: Biological Availability; Biological Transport, Active; Celecoxib; Cell Line; Chemistry, Pharmaceutic

2013
Effect of diabetes on transscleral delivery of celecoxib.
    Pharmaceutical research, 2009, Volume: 26, Issue:2

    Topics: Animals; Area Under Curve; Blood Glucose; Blood-Retinal Barrier; Body Weight; Capillary Permeability

2009
Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase

2004
Drug intervention can correct subnormal retinal oxygenation response in experimental diabetic retinopathy.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:8

    Topics: Animals; Blood Glucose; Carbon Dioxide; Celecoxib; Cyclooxygenase Inhibitors; Diabetes Mellitus, Exp

2005
Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:3

    Topics: Animals; Blood-Retinal Barrier; Capillary Permeability; Celecoxib; Cell Culture Techniques; Cyclooxy

2006