celecoxib has been researched along with Diabetic Nephropathies in 4 studies
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There was no significant difference in urinary proteinuria after 6 weeks of treatment with placebo or celecoxib (proteinuria ratio, celecoxib versus placebo, 1." | 9.12 | A randomized trial of a 6-week course of celecoxib on proteinuria in diabetic kidney disease. ( Chen, H; Clyne, S; Han, E; Harris, R; Lehrich, R; Lewis, J; Middleton, J; Rodby, R; Schulman, G; Shyr, Y; Sika, M; Sinsakul, M, 2007) |
| "There was no significant difference in urinary proteinuria after 6 weeks of treatment with placebo or celecoxib (proteinuria ratio, celecoxib versus placebo, 1." | 5.12 | A randomized trial of a 6-week course of celecoxib on proteinuria in diabetic kidney disease. ( Chen, H; Clyne, S; Han, E; Harris, R; Lehrich, R; Lewis, J; Middleton, J; Rodby, R; Schulman, G; Shyr, Y; Sika, M; Sinsakul, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nasrallah, R | 3 |
| Robertson, SJ | 1 |
| Karsh, J | 1 |
| Hébert, RL | 3 |
| Sinsakul, M | 1 |
| Sika, M | 1 |
| Rodby, R | 1 |
| Middleton, J | 1 |
| Shyr, Y | 1 |
| Chen, H | 1 |
| Han, E | 1 |
| Lehrich, R | 1 |
| Clyne, S | 1 |
| Schulman, G | 1 |
| Harris, R | 1 |
| Lewis, J | 1 |
| Cherney, DZ | 2 |
| Miller, JA | 2 |
| Scholey, JW | 2 |
| Bradley, TJ | 2 |
| Slorach, C | 2 |
| Curtis, JR | 1 |
| Dekker, MG | 2 |
| Sochett, EB | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00065559] | 30 participants | Interventional | 2003-04-30 | Terminated | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for celecoxib and Diabetic Nephropathies
| Article | Year |
|---|---|
A randomized trial of a 6-week course of celecoxib on proteinuria in diabetic kidney disease.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Celecoxib; Creatinine; Cross-Over Studies; | 2007 |
The effect of cyclooxygenase-2 inhibition on renal hemodynamic function in humans with type 1 diabetes.
Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabetes Mellitus, Type | 2008 |
Renal hemodynamic effect of cyclooxygenase 2 inhibition in young men and women with uncomplicated type 1 diabetes mellitus.
Topics: Adolescent; Adult; Angiotensin II; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabete | 2008 |
1 other study available for celecoxib and Diabetic Nephropathies
| Article | Year |
|---|---|
Celecoxib modifies glomerular basement membrane, mesangium and podocytes in OVE26 mice, but ibuprofen is more detrimental.
Topics: Albumins; Animals; Blood Glucose; Blood Pressure; Celecoxib; Creatinine; Cyclin-Dependent Kinase Inh | 2013 |