celecoxib has been researched along with Depressive Disorder in 8 studies
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Celecoxib as add-on strategy resulted in a significant reduction of Hamilton Depression Scale scores compared to placebo." | 9.15 | Elevated macrophage migration inhibitory factor and decreased transforming growth factor-beta levels in major depression--no influence of celecoxib treatment. ( Arolt, V; Cerovecki, A; Dehning, S; Müller, N; Musil, R; Riedel, M; Schwarz, MJ; Spellmann, I, 2011) |
| "Celecoxib as add-on strategy resulted in a significant reduction of Hamilton Depression Scale scores compared to placebo." | 5.15 | Elevated macrophage migration inhibitory factor and decreased transforming growth factor-beta levels in major depression--no influence of celecoxib treatment. ( Arolt, V; Cerovecki, A; Dehning, S; Müller, N; Musil, R; Riedel, M; Schwarz, MJ; Spellmann, I, 2011) |
| "Five RCTs (four unipolar depression studies and one bipolar depression study) were included in the systematic review for qualitative data synthesis." | 2.50 | Celecoxib: a new augmentation strategy for depressive mood episodes. A systematic review and meta-analysis of randomized placebo-controlled trials. ( Farid, L; Faridhosseini, F; Pourgholami, M; Sadeghi, R, 2014) |
| " In order to probe an alternative dosing design that would preclude this effect, we studied the efficacy of a low dose of the antidepressant imipramine (7 mg/kg/day) delivered via food pellets." | 1.42 | Animal Models of Depression and Drug Delivery with Food as an Effective Dosing Method: Evidences from Studies with Celecoxib and Dicholine Succinate. ( Araújo-Correia, M; Cline, BH; Costa-Nunes, JP; Dolgov, O; Kubatiev, A; Markova, N; Steinbusch, HW; Strekalova, T; Valença, A; Yeritsyan, N, 2015) |
| "Celecoxib was administrated by oral gavage to naive rats (16 mg/kg) or stressed rats (2, 8, 16 mg/kg, respectively) for 21 days, or to stressed rats for a single dose (16 mg/kg)." | 1.35 | Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain. ( Guo, JY; Li, CY; Luo, F; Qi, XL; Ruan, YP; Sun, M; Zhao, BS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faridhosseini, F | 1 |
| Sadeghi, R | 1 |
| Farid, L | 1 |
| Pourgholami, M | 1 |
| Costa-Nunes, JP | 1 |
| Cline, BH | 1 |
| Araújo-Correia, M | 1 |
| Valença, A | 1 |
| Markova, N | 1 |
| Dolgov, O | 1 |
| Kubatiev, A | 1 |
| Yeritsyan, N | 1 |
| Steinbusch, HW | 1 |
| Strekalova, T | 1 |
| Song, C | 1 |
| Zhang, XY | 1 |
| Manku, M | 1 |
| Guo, JY | 1 |
| Li, CY | 1 |
| Ruan, YP | 1 |
| Sun, M | 1 |
| Qi, XL | 1 |
| Zhao, BS | 1 |
| Luo, F | 1 |
| Davis, A | 1 |
| Gilhooley, M | 1 |
| Agius, M | 1 |
| Musil, R | 1 |
| Schwarz, MJ | 2 |
| Riedel, M | 2 |
| Dehning, S | 2 |
| Cerovecki, A | 2 |
| Spellmann, I | 2 |
| Arolt, V | 2 |
| Müller, N | 2 |
| Rastogi, R | 1 |
| Swarm, RA | 1 |
| Patel, TA | 1 |
| Douhe, A | 1 |
| Goldstein-Müller, B | 1 |
| Hetzel, G | 1 |
| Maino, K | 1 |
| Kleindienst, N | 1 |
| Möller, HJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of a Sea-safety Course on Mood, Mental Wellbeing and Inflammation[NCT04528485] | 61 participants (Actual) | Interventional | 2020-07-01 | Completed | |||
| Minocycline as an Adjunct for the Treatment of Depressive Symptoms: Pilot Randomized Controlled Trial[NCT02263872] | Phase 4 | 41 participants (Actual) | Interventional | 2014-10-31 | Completed | ||
| Salicylic Augmentation in Depression[NCT03152409] | Phase 2 | 74 participants (Anticipated) | Interventional | 2018-11-15 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for celecoxib and Depressive Disorder
| Article | Year |
|---|---|
Celecoxib: a new augmentation strategy for depressive mood episodes. A systematic review and meta-analysis of randomized placebo-controlled trials.
Topics: Antidepressive Agents; Bipolar Disorder; Celecoxib; Cyclooxygenase 2 Inhibitors; Depressive Disorder | 2014 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhi | 2011 |
2 trials available for celecoxib and Depressive Disorder
4 other studies available for celecoxib and Depressive Disorder
| Article | Year |
|---|---|
Animal Models of Depression and Drug Delivery with Food as an Effective Dosing Method: Evidences from Studies with Celecoxib and Dicholine Succinate.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Celecoxib; Depressive Disorder; Disease Models, An | 2015 |
Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment.
Topics: Analysis of Variance; Animals; Celecoxib; Corticosterone; Corticotropin-Releasing Hormone; Cyclooxyg | 2009 |
Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain.
Topics: Animals; Brain; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Depressive Disorder; Gene | 2009 |
Using non-steroidal anti-inflammatory drugs in the treatment of depression.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Celecoxib; Depressive Disorder; Doub | 2010 |