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celecoxib and Degenerative Diseases, Central Nervous System

celecoxib has been researched along with Degenerative Diseases, Central Nervous System in 9 studies

Research Excerpts

ExcerptRelevanceReference
"This study aimed to evaluate the safety and tolerability of a fixed-dose co-formulation of ciprofloxacin and celecoxib (PrimeC) in patients with amyotrophic lateral sclerosis (ALS), and to examine its effects on disease progression and ALS-related biomarkers."5.69Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS. ( Abramovich, B; Beaulieu, D; Berry, JD; Birman, N; Drory, VE; Eitan, E; Elgrart, K; Ennist, DL; Paganoni, S; Pushett, A; Russek-Blum, N; Salomon-Zimri, S; Shefner, JM; Van Eijk, RPA, 2023)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Swarbrick, ME1
Beswick, PJ1
Gleave, RJ1
Green, RH1
Bingham, S1
Bountra, C1
Carter, MC1
Chambers, LJ1
Chessell, IP1
Clayton, NM1
Collins, SD1
Corfield, JA1
Hartley, CD1
Kleanthous, S1
Lambeth, PF1
Lucas, FS1
Mathews, N1
Naylor, A1
Page, LW1
Payne, JJ1
Pegg, NA1
Price, HS1
Skidmore, J1
Stevens, AJ1
Stocker, R1
Stratton, SC1
Stuart, AJ1
Wiseman, JO1
Salomon-Zimri, S1
Pushett, A1
Russek-Blum, N1
Van Eijk, RPA1
Birman, N1
Abramovich, B1
Eitan, E1
Elgrart, K1
Beaulieu, D1
Ennist, DL1
Berry, JD1
Paganoni, S1
Shefner, JM1
Drory, VE1
Al Kury, LT1
Zeb, A1
Abidin, ZU1
Irshad, N1
Malik, I1
Alvi, AM1
Khalil, AAK1
Ahmad, S1
Faheem, M1
Khan, AU1
Shah, FA1
Li, S1
Gholizadeh, E1
Karbalaei, R1
Khaleghian, A1
Salimi, M1
Gilany, K1
Soliymani, R1
Tanoli, Z1
Rezadoost, H1
Baumann, M1
Jafari, M1
Tang, J1
Villa, V1
Thellung, S1
Bajetto, A1
Gatta, E1
Robello, M1
Novelli, F1
Tasso, B1
Tonelli, M1
Florio, T1
Borre, Y1
Lemstra, S1
Westphal, KG1
Morgan, ME1
Olivier, B1
Oosting, RS1
Casolini, P1
Catalani, A1
Zuena, AR1
Angelucci, L1
Sairam, K1
Saravanan, KS1
Banerjee, R1
Mohanakumar, KP1
Gobbo, OL1
O'Mara, SM1

Trials

1 trial available for celecoxib and Degenerative Diseases, Central Nervous System

ArticleYear
Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS.
    Amyotrophic lateral sclerosis & frontotemporal degeneration, 2023, Volume: 24, Issue:3-4

    Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Celecoxib; Ciprofloxacin; COVID-19; Disease Progression;

2023

Other Studies

8 other studies available for celecoxib and Degenerative Diseases, Central Nervous System

ArticleYear
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Amines; Animals; Brain; Chemistry, Pharmaceutical; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Di

2009
Neuroprotective effects of melatonin and celecoxib against ethanol-induced neurodegeneration: a computational and pharmacological approach.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Animals; Celecoxib; Computational Biology; Disease Models, Animal; Ethanol; Injections, Intraperiton

2019
Identification of Celecoxib-Targeted Proteins Using Label-Free Thermal Proteome Profiling on Rat Hippocampus.
    Molecular pharmacology, 2021, Volume: 99, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chromatography, Liquid; Gene Expression

2021
Novel celecoxib analogues inhibit glial production of prostaglandin E2, nitric oxide, and oxygen radicals reverting the neuroinflammatory responses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide.
    Pharmacological research, 2016, Volume: 113, Issue:Pt A

    Topics: Animals; Astrocytes; Celecoxib; Cell Line; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Infla

2016
Celecoxib delays cognitive decline in an animal model of neurodegeneration.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: Analysis of Variance; Animals; Celecoxib; Cognition Disorders; Cyclooxygenase 2 Inhibitors; Cytokine

2012
Inhibition of COX-2 reduces the age-dependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat.
    Journal of neuroscience research, 2002, May-01, Volume: 68, Issue:3

    Topics: Aging; Animals; Celecoxib; Cognition Disorders; Corticosterone; Cyclooxygenase 2; Cyclooxygenase 2 I

2002
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
    Brain research, 2003, Mar-21, Volume: 966, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Corpus Str

2003
Post-treatment, but not pre-treatment, with the selective cyclooxygenase-2 inhibitor celecoxib markedly enhances functional recovery from kainic acid-induced neurodegeneration.
    Neuroscience, 2004, Volume: 125, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Celecoxib; Cell

2004