celecoxib and Cushing Syndrome studies

Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.

Research Excerpts

Excerpt	Relevance	Reference
"Celecoxib treatment led to decreased PGE2 and corticosterone levels, reduced proliferation and increased apoptosis of adrenocortical cells, and decreased steroidogenic gene expression."	5.43	Celecoxib reduces glucocorticoids in vitro and in a mouse model with adrenocortical hyperplasia. ( Berthon, A; Faucz, FR; Liu, S; Martinez, A; Sahut-Barnola, I; Saloustros, E; Salpea, P; Starost, MF; Stratakis, CA; Szarek, E, 2016)
"Celecoxib treatment led to decreased PGE2 and corticosterone levels, reduced proliferation and increased apoptosis of adrenocortical cells, and decreased steroidogenic gene expression."	1.43	Celecoxib reduces glucocorticoids in vitro and in a mouse model with adrenocortical hyperplasia. ( Berthon, A; Faucz, FR; Liu, S; Martinez, A; Sahut-Barnola, I; Saloustros, E; Salpea, P; Starost, MF; Stratakis, CA; Szarek, E, 2016)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

celecoxib and Cushing Syndrome

Research Excerpts

Research

Studies (1)

Authors

Other Studies

Authors	Studies
Liu, S	1
Saloustros, E	1
Berthon, A	1
Starost, MF	1
Sahut-Barnola, I	1
Salpea, P	1
Szarek, E	1
Faucz, FR	1
Martinez, A	1
Stratakis, CA	1