celecoxib has been researched along with Complication, Postoperative in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " We evaluated rates of acute kidney injury (AKI) in primary and revision TJA using a multimodal pain control regimen including scheduled celecoxib and PRN ketorolac." | 7.83 | Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib. ( Callaghan, JJ; Hogue, MH; Klaassen, AL; Liu, SS; Noiseux, NO; Warth, LC, 2016) |
| " Timing of administration, inadequate dosing and possible altered pharmacokinetics in pregnancy may explain the lack of efficacy." | 6.71 | The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section. ( Irwin, MG; Lee, LH; Lim, J; Wong, CK, 2004) |
| "To determine whether prostaglandin inhibition by cyclooxygenase inhibitors, celecoxib or diclofenac, could enhance gastrointestinal recovery and reduce post-operative ileus in humans." | 5.14 | Clinical trial: the impact of cyclooxygenase inhibitors on gastrointestinal recovery after major surgery - a randomized double blind controlled trial of celecoxib or diclofenac vs. placebo. ( Bampton, PA; Costa, M; De Fontgalland, D; Leach, PL; McLaughlin, K; Wattchow, DA, 2009) |
| " The purpose of this study was to use a validated rabbit model to assess the effects on surgically-induced knee joint contractures of two combined pharmacological interventions: celecoxib (CXB) loaded on an implanted collagen membrane, and subcutaneously (SQ) injected ketotifen." | 3.96 | Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen. ( Abdel, MP; Berry, CE; Berry, DJ; Bolon, B; Carter, JM; Jay, AG; Limberg, AK; McLaury, AR; Morrey, ME; Salib, CG; Sanchez-Sotelo, J; Tibbo, ME; Turner, TW; van Wijnen, AJ, 2020) |
| " We evaluated rates of acute kidney injury (AKI) in primary and revision TJA using a multimodal pain control regimen including scheduled celecoxib and PRN ketorolac." | 3.83 | Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib. ( Callaghan, JJ; Hogue, MH; Klaassen, AL; Liu, SS; Noiseux, NO; Warth, LC, 2016) |
| "The primary endpoint was postoperative pain and adverse events, and the secondary endpoint was the length of the analgesic procedure and physiological function on postoperative day 1." | 2.94 | Intercostal block vs. epidural analgesia in thoracoscopic lung cancer surgery: a randomized trial. ( Hamano, K; Hayashi, M; Murakami, J; Tanaka, T; Ueda, K; Utada, K, 2020) |
| "Celecoxib 400 mg was significantly more effective than 200 mg (and placebo) in reducing postoperative pain." | 2.71 | The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study. ( Issioui, T; Klein, K; Recart, A; Shah, M; Stool, L; Watcha, MF; White, PF, 2003) |
| " Timing of administration, inadequate dosing and possible altered pharmacokinetics in pregnancy may explain the lack of efficacy." | 2.71 | The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section. ( Irwin, MG; Lee, LH; Lim, J; Wong, CK, 2004) |
| "Heterotopic ossification is a common complication following total hip arthroplasty and surgery following acetabular trauma." | 2.44 | Pharmacological treatment of heterotopic ossification following hip and acetabular surgery. ( El Masry, MA; Gamie, Z; Macfarlane, RJ; Ng, BH; Schizas, C; Tsiridis, E; Velonis, S, 2008) |
| "The pharmacological prophylaxis of heterotopic ossification (HO) following total hip arthroplasty (THA) is debated." | 1.72 | A comprehensive update on the pharmacological management of heterotopic ossification following hip arthroplasty: a level I evidenced based expert opinion. ( Asparago, G; Cuozzo, F; Maffulli, N; Migliorini, F; Oliva, F, 2022) |
| "Celecoxib did not inhibit the progression of initiated HO in the patients in whom HO was diagnosed, whereas those who received celecoxib after surgery had lower morbidity." | 1.51 | Celecoxib cannot inhibit the progression of initiated traumatic heterotopic ossification. ( Li, F; Mao, D; Mi, J; Pan, X; Rui, Y; Zhang, X, 2019) |
| "Outcome measures were postsurgical pain at rest and during walking, consumption of opioids for pain rescue, knee swelling and knee range of motion, and complications." | 1.46 | Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty. ( Hansen, TB; Munk, S; Rytter, S; Stilling, M, 2017) |
| "The overall incidence of heterotopic ossification in the celecoxib-treated patients was 23% (no cases of Brooker grade 3 or 4 ossifications), compared to 55% in the untreated patients (Brooker grade 3 and 4: 8." | 1.38 | Adherence to routine use of pharmacological prophylaxis of heterotopic ossification after total hip arthroplasty: results from an Italian multicenter, prospective, observational survey. ( Barbato, M; Cavasinni, L; D'Angelo, E; Di Francesco, A; Di Loreto, G; La Floresta, P; Menna, A; Romanò, CL; Salini, V; Zoppi, U, 2012) |
| "Up to 30% of cancer patients undergoing curative surgery develop local recurrences due to positive margins." | 1.38 | A positive-margin resection model recreates the postsurgical tumor microenvironment and is a reliable model for adjuvant therapy evaluation. ( Aliperti, LA; Cheng, G; Fridlender, ZG; Judy, B; Kapoor, V; Madajewski, B; Okusanya, O; Predina, JD; Quatromoni, J; Singhal, S, 2012) |
| "We investigated the safety and efficacy of the bilateral periarticular multimodal drug injection (PMDI) at a reduced dosage in patients undergoing simultaneous bilateral total knee arthroplasty (SBTKA)." | 1.38 | Use of reduced-dose periarticular injection for pain management in simultaneous bilateral total knee arthroplasty. ( Chang, CB; Jeon, YT; Kang, YG; Kim, TK; Koh, IJ; Song, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 5 (19.23) | 2.80 |
| Authors | Studies |
|---|---|
| Migliorini, F | 1 |
| Asparago, G | 1 |
| Oliva, F | 1 |
| Cuozzo, F | 1 |
| Maffulli, N | 1 |
| Ueda, K | 1 |
| Hayashi, M | 1 |
| Murakami, J | 1 |
| Tanaka, T | 1 |
| Utada, K | 1 |
| Hamano, K | 1 |
| Li, F | 1 |
| Mao, D | 1 |
| Pan, X | 1 |
| Zhang, X | 1 |
| Mi, J | 1 |
| Rui, Y | 1 |
| Ochiai, D | 1 |
| Adib, F | 1 |
| Limberg, AK | 1 |
| Tibbo, ME | 1 |
| Salib, CG | 1 |
| McLaury, AR | 1 |
| Turner, TW | 1 |
| Berry, CE | 1 |
| Jay, AG | 1 |
| Carter, JM | 1 |
| Bolon, B | 1 |
| Berry, DJ | 1 |
| Morrey, ME | 1 |
| Sanchez-Sotelo, J | 1 |
| van Wijnen, AJ | 1 |
| Abdel, MP | 1 |
| Naylor, BH | 1 |
| Iturriaga, CR | 1 |
| Bisen, YB | 1 |
| Caid, MJ | 1 |
| Reinhardt, KR | 1 |
| Parsa, FD | 1 |
| Cheng, J | 1 |
| Stephan, B | 1 |
| Castel, N | 1 |
| Kim, L | 1 |
| Murariu, D | 1 |
| Parsa, AA | 1 |
| Rytter, S | 1 |
| Stilling, M | 1 |
| Munk, S | 1 |
| Hansen, TB | 1 |
| Warth, LC | 1 |
| Noiseux, NO | 1 |
| Hogue, MH | 1 |
| Klaassen, AL | 1 |
| Liu, SS | 1 |
| Callaghan, JJ | 1 |
| Raju, DP | 1 |
| Hakendorf, P | 1 |
| Costa, M | 2 |
| Wattchow, DA | 2 |
| Holte, K | 1 |
| Andersen, J | 1 |
| Jakobsen, DH | 1 |
| Kehlet, H | 1 |
| De Fontgalland, D | 1 |
| Bampton, PA | 1 |
| Leach, PL | 1 |
| McLaughlin, K | 1 |
| Guvenal, T | 1 |
| Yanar, O | 1 |
| Timuroglu, Y | 1 |
| Cetin, M | 1 |
| Cetin, A | 1 |
| Klein, M | 1 |
| Gögenur, I | 1 |
| Rosenberg, J | 1 |
| Barbato, M | 1 |
| D'Angelo, E | 1 |
| Di Loreto, G | 1 |
| Menna, A | 1 |
| Di Francesco, A | 1 |
| Salini, V | 1 |
| Zoppi, U | 1 |
| Cavasinni, L | 1 |
| La Floresta, P | 1 |
| Romanò, CL | 1 |
| Davis, JL | 1 |
| Yi, NY | 1 |
| Salmon, JH | 1 |
| Charlton, AN | 1 |
| Colitz, CM | 1 |
| Gilger, BC | 1 |
| Predina, JD | 1 |
| Judy, B | 1 |
| Fridlender, ZG | 1 |
| Aliperti, LA | 1 |
| Madajewski, B | 1 |
| Kapoor, V | 1 |
| Cheng, G | 1 |
| Quatromoni, J | 1 |
| Okusanya, O | 1 |
| Singhal, S | 1 |
| Koh, IJ | 1 |
| Kang, YG | 1 |
| Chang, CB | 1 |
| Song, J | 1 |
| Jeon, YT | 1 |
| Kim, TK | 1 |
| Shafiq, N | 1 |
| Malhotra, S | 1 |
| Pandhi, P | 1 |
| Recart, A | 1 |
| Issioui, T | 1 |
| White, PF | 1 |
| Klein, K | 1 |
| Watcha, MF | 1 |
| Stool, L | 1 |
| Shah, M | 1 |
| Lee, LH | 1 |
| Irwin, MG | 1 |
| Lim, J | 1 |
| Wong, CK | 1 |
| Reuben, SS | 2 |
| Ackerman, WE | 1 |
| Ahmad, M | 1 |
| Macfarlane, RJ | 1 |
| Ng, BH | 1 |
| Gamie, Z | 1 |
| El Masry, MA | 1 |
| Velonis, S | 1 |
| Schizas, C | 1 |
| Tsiridis, E | 1 |
| Smiles, J | 1 |
| Walker, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficiency of Opioid-free Anesthesia (OFA) in Maxillofacial Surgery[NCT05031676] | 66 participants (Actual) | Interventional | 2019-02-15 | Completed | |||
| The Effect of Preoperative Steroids Injection on Pain and Oedema After Total Knee Arthroplasty . A Double -Blinded Randomized Controlled Study.[NCT04084912] | Phase 3 | 86 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | ||
| Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand[NCT05003596] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for celecoxib and Complication, Postoperative
| Article | Year |
|---|---|
Pharmacological treatment of heterotopic ossification following hip and acetabular surgery.
Topics: Acetabulum; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Celecoxib; Dicl | 2008 |
5 trials available for celecoxib and Complication, Postoperative
| Article | Year |
|---|---|
Intercostal block vs. epidural analgesia in thoracoscopic lung cancer surgery: a randomized trial.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics; Celecoxib; Female; Humans; Japan; Lung Neoplasms; Male | 2020 |
Efficacy and safety of low-dose celecoxib in reducing post-operative paralytic ileus after major abdominal surgery.
Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Anastomotic Leak; Celecoxib; Colectomy; Cycloox | 2015 |
Clinical trial: the impact of cyclooxygenase inhibitors on gastrointestinal recovery after major surgery - a randomized double blind controlled trial of celecoxib or diclofenac vs. placebo.
Topics: Adult; Aged; Aged, 80 and over; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Metho | 2009 |
The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Anesthe | 2003 |
The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Antipruritics; Celecoxib; Ce | 2004 |
20 other studies available for celecoxib and Complication, Postoperative
| Article | Year |
|---|---|
A comprehensive update on the pharmacological management of heterotopic ossification following hip arthroplasty: a level I evidenced based expert opinion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Celecoxib; Diclofenac; Expe | 2022 |
Celecoxib cannot inhibit the progression of initiated traumatic heterotopic ossification.
Topics: Achilles Tendon; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Disease M | 2019 |
Editorial Commentary: The Curious Incident of the Bone in the Soft Tissue: Is Heterotopic Ossification After Hip Arthroscopy an Interesting Finding or Is It a Complication?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arthroscopy; Celecoxib; Cyc | 2020 |
Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen.
Topics: Animals; Celecoxib; Contracture; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Delivery | 2020 |
Heterotopic Ossification Following Direct Anterior Total Hip Arthroplasty With and Without Postoperative Analgesic Nonsteroidal Anti-inflammatories.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Celecoxib; Humans; Ossifica | 2021 |
Bilateral Breast Reduction Without Opioid Analgesics: A Comparative Study.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthesia, Local; | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arthro | 2016 |
Cyclo-oxygenase 2 inhibitors and the risk of anastomotic leakage after fast-track colonic surgery.
Topics: Aged; Aged, 80 and over; Anastomosis, Surgical; Celecoxib; Colectomy; Colonic Diseases; Cyclooxygena | 2009 |
Effects of selective and non-selective cyclooxygenase (COX) inhibitors on postoperative adhesion formation in a rat uterine horn model.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Female; Indomethacin; Postoperative Complications; Py | 2010 |
[Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs].
Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 | 2010 |
Adherence to routine use of pharmacological prophylaxis of heterotopic ossification after total hip arthroplasty: results from an Italian multicenter, prospective, observational survey.
Topics: Arthroplasty, Replacement, Hip; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, | 2012 |
Sustained-release celecoxib from incubated acrylic intraocular lenses suppresses lens epithelial cell growth in an ex vivo model of posterior capsule opacity.
Topics: Animals; Cataract Extraction; Celecoxib; Corneal Opacity; Cyclooxygenase 2 Inhibitors; Delayed-Actio | 2012 |
A positive-margin resection model recreates the postsurgical tumor microenvironment and is a reliable model for adjuvant therapy evaluation.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Celecoxib; Cell Line, Tumor; Chemotherapy, A | 2012 |
Use of reduced-dose periarticular injection for pain management in simultaneous bilateral total knee arthroplasty.
Topics: Aged; Amides; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Anti-Bacterial Agents; Art | 2012 |
Effect of cyclooxygenase inhibitors in postoperative ileus: an experimental study.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Indomethaci | 2002 |
The prevention of post-surgical neuralgia.
Topics: Analgesics; Celecoxib; Cyclohexanols; Cyclooxygenase Inhibitors; Double-Blind Method; Humans; Incide | 2005 |
The safety of the perioperative administration of cyclooxygenase-2 inhibitors for post-surgical pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty; Blood Loss, Surgical; Celecoxib; Child; Cyclo | 2005 |
Recurrent postoperative CRPS I in patients with abnormal preoperative sympathetic function.
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerve Block; Carpal Tu | 2008 |
Selective cyclo-oxygenase-2 inhibitor-induced oliguria: a postoperative complication.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2001 |