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celecoxib and Colitis

celecoxib has been researched along with Colitis in 16 studies

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
" This study tried to investigate whether an apple oligogalactan (AOG) could enhance the growth inhibitory effect of celecoxib on colorectal cancer."7.80An apple oligogalactan potentiates the growth inhibitory effect of celecoxib on colorectal cancer. ( Chen, J; Li, Q; Li, Y; Liu, L; Mei, L; Mei, Q; Niu, Y; Sun, Y; Zhang, B; Zhang, R, 2014)
" The aim of this study was 1) to evaluate the relative importance of the GI microflora on the experimental colonic damage in the presence of caused by NSAID, and 2) to assess the efficacy of antibiotic treatment with ampicillin on the process of healing of colitis."7.77Antibiotic treatment with ampicillin accelerates the healing of colonic damage impaired by aspirin and coxib in the experimental colitis. Importance of intestinal bacteria, colonic microcirculation and proinflammatory cytokines. ( Brzozowski, T; Drozdowicz, D; Karczewska, E; Konturek, SJ; Krzysiek-Maczka, G; Pajdo, R; Pawlik, WW; Ptak-Belowska, A; Sliwowski, Z; Urbanczyk, K; Zwolinska-Wcislo, M, 2011)
"To assess the mechanism of exacerbation of colonic damage in rat colitis model induced by trinitrobenzene sulfonic acid (TNBS) treated with celecoxib (a selective COX-2 inhibitor)."7.74[Mechanism of exacerbation of colonic damage in experimental colitis treated with celecoxib]. ( Dong, Xy; Lv, Ym; Ye, Sm; Zhang, L, 2008)
"To investigate the action of celecoxib (a selective COX-2 inhibitor) in a rat model of colitis induced by trinitrobenzene sulfonic acid (TNBS)."7.72Effects and mechanism of the selective COX-2 inhibitor, celecoxib, on rat colitis induced by trinitrobenzene sulfonic acid. ( Dong, XY; Lu, YM; Zhang, L, 2004)
" Here, we investigate the effects of the selective cyclo-oxygenase-2 inhibitor, celecoxib, in rats subjected to experimental colitis."7.71Celecoxib, a selective cyclo-oxygenase-2 inhibitor reduces the severity of experimental colitis induced by dinitrobenzene sulfonic acid in rats. ( Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; Dugo, L; Mazzon, E; Sautebin, L; Serraino, I, 2001)
"Acetic acid treatment caused haemorrhagic diarrhoea and weight loss in rats."5.33The effects of selective cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, on experimental colitis induced by acetic acid in rats. ( Arafa, M; El-Medany, A; Mahgoub, A; Morsi, M; Mustafa, A, 2005)
" Colonic delivery of celecoxib elicits anticolitic effects in a trinitrobenzene sulfonic acid-induced rat colitis model."3.81Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-κB, an anti-inflammatory target. ( Jeong, S; Jung, Y; Kim, MS; Kim, W; Lee, S; Lee, Y; Moon, HR; Nam, J; Yoo, JW, 2015)
" This study tried to investigate whether an apple oligogalactan (AOG) could enhance the growth inhibitory effect of celecoxib on colorectal cancer."3.80An apple oligogalactan potentiates the growth inhibitory effect of celecoxib on colorectal cancer. ( Chen, J; Li, Q; Li, Y; Liu, L; Mei, L; Mei, Q; Niu, Y; Sun, Y; Zhang, B; Zhang, R, 2014)
" The aim of this study was 1) to evaluate the relative importance of the GI microflora on the experimental colonic damage in the presence of caused by NSAID, and 2) to assess the efficacy of antibiotic treatment with ampicillin on the process of healing of colitis."3.77Antibiotic treatment with ampicillin accelerates the healing of colonic damage impaired by aspirin and coxib in the experimental colitis. Importance of intestinal bacteria, colonic microcirculation and proinflammatory cytokines. ( Brzozowski, T; Drozdowicz, D; Karczewska, E; Konturek, SJ; Krzysiek-Maczka, G; Pajdo, R; Pawlik, WW; Ptak-Belowska, A; Sliwowski, Z; Urbanczyk, K; Zwolinska-Wcislo, M, 2011)
"To assess the mechanism of exacerbation of colonic damage in rat colitis model induced by trinitrobenzene sulfonic acid (TNBS) treated with celecoxib (a selective COX-2 inhibitor)."3.74[Mechanism of exacerbation of colonic damage in experimental colitis treated with celecoxib]. ( Dong, Xy; Lv, Ym; Ye, Sm; Zhang, L, 2008)
" Celecoxib (10, 20 and 40 mg/kg(-l)) was significantly more potent at aggravating ischemia-reperfusion injury as compared to nimesulide."3.73Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors. ( Malhotra, S; Nada, R; Pandhi, P; Shafiq, N, 2005)
"To investigate the action of celecoxib (a selective COX-2 inhibitor) in a rat model of colitis induced by trinitrobenzene sulfonic acid (TNBS)."3.72Effects and mechanism of the selective COX-2 inhibitor, celecoxib, on rat colitis induced by trinitrobenzene sulfonic acid. ( Dong, XY; Lu, YM; Zhang, L, 2004)
" Here, we investigate the effects of the selective cyclo-oxygenase-2 inhibitor, celecoxib, in rats subjected to experimental colitis."3.71Celecoxib, a selective cyclo-oxygenase-2 inhibitor reduces the severity of experimental colitis induced by dinitrobenzene sulfonic acid in rats. ( Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; Dugo, L; Mazzon, E; Sautebin, L; Serraino, I, 2001)
"Colitis was induced by intracolonic administration of trinitrobenzene sulfonic acid."1.31Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis. ( Ajuebor, MN; Singh, A; Wallace, JL, 2000)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (50.00)29.6817
2010's7 (43.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Kaur, R1
Desai, D1
Amin, S1
Raza, K1
Bhalla, A1
Yadav, P1
Kaushal, N1
Li, Y1
Niu, Y1
Sun, Y1
Mei, L1
Zhang, B1
Li, Q1
Liu, L1
Zhang, R1
Chen, J1
Mei, Q1
Lee, Y2
Kim, W2
Hong, S1
Park, H1
Yum, S1
Yoon, JH1
Jung, Y2
Setia, S1
Nehru, B1
Sanyal, SN1
Lee, S1
Nam, J1
Jeong, S1
Yoo, JW1
Kim, MS1
Moon, HR1
Pallio, G1
Bitto, A1
Pizzino, G1
Galfo, F1
Irrera, N1
Minutoli, L1
Arcoraci, V1
Squadrito, G1
Macrì, A1
Squadrito, F1
Altavilla, D1
Carothers, AM1
Davids, JS1
Damas, BC1
Bertagnolli, MM1
Zwolinska-Wcislo, M1
Krzysiek-Maczka, G1
Ptak-Belowska, A1
Karczewska, E1
Pajdo, R1
Sliwowski, Z1
Urbanczyk, K1
Drozdowicz, D1
Konturek, SJ1
Pawlik, WW1
Brzozowski, T1
Hegazi, RA1
Mady, HH1
Melhem, MF1
Sepulveda, AR1
Mohi, M1
Kandil, HM1
Zhang, L2
Lu, YM1
Dong, XY2
El-Medany, A1
Mahgoub, A1
Mustafa, A1
Arafa, M1
Morsi, M1
Shafiq, N1
Malhotra, S1
Pandhi, P1
Nada, R1
Houmani, Z1
Imbert, A1
Duchmann, JC1
Messerschmitt, C1
Barbare, JC1
Latrive, JP1
Biour, M1
Lv, Ym1
Ye, Sm1
Ajuebor, MN1
Singh, A1
Wallace, JL1
Cuzzocrea, S1
Mazzon, E1
Serraino, I1
Dugo, L1
Centorrino, T1
Ciccolo, A1
Sautebin, L1
Caputi, AP1

Other Studies

16 other studies available for celecoxib and Colitis

ArticleYear
Selenocoxib-3, a novel anti-inflammatory therapeutic effectively resolves colitis.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis; Coli

2023
An apple oligogalactan potentiates the growth inhibitory effect of celecoxib on colorectal cancer.
    Nutrition and cancer, 2014, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Caco-2 Cells; Celecoxib; Cell Proliferation

2014
Colon-targeted celecoxib ameliorates TNBS-induced rat colitis: a potential pharmacologic mechanism and therapeutic advantages.
    European journal of pharmacology, 2014, Mar-05, Volume: 726

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cell Line; Colitis; Colon; Cyclooxygenase 2 Inhibi

2014
The PI3K/Akt pathway in colitis associated colon cancer and its chemoprevention with celecoxib, a Cox-2 selective inhibitor.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2014, Volume: 68, Issue:6

    Topics: Animals; Celecoxib; Chemoprevention; Colitis; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Mice;

2014
Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-κB, an anti-inflammatory target.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Anti-Inflammatory Agents; Celecoxib; Cell Line; Colitis; Colon; Drug Delivery Systems; Drug

2015
Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.
    European journal of pharmacology, 2016, Oct-15, Volume: 789

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Body Weight; Catechin

2016
Persistent cyclooxygenase-2 inhibition downregulates NF-{kappa}B, resulting in chronic intestinal inflammation in the min/+ mouse model of colon tumorigenesis.
    Cancer research, 2010, Jun-01, Volume: 70, Issue:11

    Topics: Animals; Antigens, CD34; Celecoxib; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Cyc

2010
Antibiotic treatment with ampicillin accelerates the healing of colonic damage impaired by aspirin and coxib in the experimental colitis. Importance of intestinal bacteria, colonic microcirculation and proinflammatory cytokines.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2011, Volume: 62, Issue:3

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacter

2011
Celecoxib and rofecoxib potentiate chronic colitis and premalignant changes in interleukin 10 knockout mice.
    Inflammatory bowel diseases, 2003, Volume: 9, Issue:4

    Topics: Animals; Celecoxib; Colitis; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Disease Models, Animal

2003
Effects and mechanism of the selective COX-2 inhibitor, celecoxib, on rat colitis induced by trinitrobenzene sulfonic acid.
    Chinese journal of digestive diseases, 2004, Volume: 5, Issue:3

    Topics: Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Inflam

2004
The effects of selective cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, on experimental colitis induced by acetic acid in rats.
    European journal of pharmacology, 2005, Jan-10, Volume: 507, Issue:1-3

    Topics: Acetic Acid; Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Lactones; Male; Pyrazoles; Rats

2005
Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:7

    Topics: Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Gastric Mucosa; Gastrointestinal Tract; Indo

2005
[Acute colitis closely following the beginning of celecoxib treatment].
    Gastroenterologie clinique et biologique, 2005, Volume: 29, Issue:12

    Topics: Acute Disease; Aged, 80 and over; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Bac

2005
[Mechanism of exacerbation of colonic damage in experimental colitis treated with celecoxib].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2008, Volume: 40, Issue:2

    Topics: Animals; Celecoxib; Colitis; Colon; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Male; Pyrazoles; Ra

2008
Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:1

    Topics: Animals; Blotting, Western; Celecoxib; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclo

2000
Celecoxib, a selective cyclo-oxygenase-2 inhibitor reduces the severity of experimental colitis induced by dinitrobenzene sulfonic acid in rats.
    European journal of pharmacology, 2001, Nov-09, Volume: 431, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Body Weight; Celecoxib; Colitis

2001