Page last updated: 2024-10-24

celecoxib and Colitis Gravis

celecoxib has been researched along with Colitis Gravis in 14 studies

Research Excerpts

ExcerptRelevanceReference
"We performed a placebo-controlled pilot trial to evaluate the safety of celecoxib in patients with ulcerative colitis in remission who had a present or past history of nonspecific arthritis, arthralgia, or other condition amenable to nonsteroidal anti-inflammatory drug therapy."5.12Safety of celecoxib in patients with ulcerative colitis in remission: a randomized, placebo-controlled, pilot study. ( Bloom, BJ; Brynskov, J; Kent, JD; Lorenz, RG; Robbins, JL; Sandborn, WJ; Steidle, GM; Stenson, WF, 2006)
"Several studies have shown the anti-neoplastic effects of non-steroidal anti-inflammatory drugs (NSAIDs) on 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis, but how these drugs act in case of inflammation-augmented tumorigenesis is still not clear."3.80Activation of NF-κB: bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis. ( Nehru, B; Sanyal, SN; Setia, S, 2014)
"A case history is described of a 38-year-old women, without digestive past, who presented with hemorrhagic ulcerated acute colitis beginning 2 days after starting celecoxib (200 mg/d) prescribed for sciatica."3.73[Ulcerating haemorrhagic colitis induced by celecoxib]. ( Andriamanantena, D; Carrère, C; Casassus-Builhè, D; Hamant, N; Perret, JL; Rey, P, 2005)
"Patients with Crohn's disease, ulcerative colitis, or pouchitis who used celecoxib or rofecoxib were identified from computerized prescription records."3.71Safety of selective cyclooxygenase-2 inhibitors in inflammatory bowel disease. ( Loftus, EV; Mahadevan, U; Sandborn, WJ; Tremaine, WJ, 2002)
" While these drugs effectively reduce musculoskeletal pain and stiffness, long-term use is limited by gastrointestinal (GI) adverse effects (AEs) and disease exacerbation."2.50Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease. ( Hu, RW; Li, HY; Li, JS; Miao, XP; Ouyang, Q; Zhang, Y, 2014)
"Treatment with celecoxib-loaded NLCs alleviated severity of colitis as demonstrated by disease activity index, colon length, fecal occult blood test, and histopathological analysis."1.56Lipid-based nanocarrier-mediated targeted delivery of celecoxib attenuate severity of ulcerative colitis. ( Ahmad, A; Khan, R; Kumar, A; Mishra, RK; Raza, SS; Vyawahare, A, 2020)
"Development of ulcerative colitis was accompanied by the activation of iNOS/COX-2/5-LOX and increased contents of nitric oxide (NO), prostaglandin E₂ (PGE₂), and leukotriene B₄ (LTB₄)."1.37Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis. ( Fomenko, IS; Panasyuk, NB; Sklyarov, AY, 2011)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's5 (35.71)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Malik, A1
Stringer, E1
Warner, N1
van Limbergen, J1
Vandersteen, A1
Muise, A1
Derfalvi, B1
Kaur, R1
Desai, D1
Amin, S1
Raza, K1
Bhalla, A1
Yadav, P1
Kaushal, N1
Mishra, RK1
Ahmad, A1
Kumar, A1
Vyawahare, A1
Raza, SS1
Khan, R1
Sheta, NM1
Boshra, SA1
Setia, S2
Nehru, B2
Sanyal, SN2
Gugulothu, D1
Kulkarni, A1
Patravale, V1
Dandekar, P1
Miao, XP1
Li, JS1
Ouyang, Q1
Hu, RW1
Zhang, Y1
Li, HY1
Sklyarov, AY1
Panasyuk, NB1
Fomenko, IS1
Rey, P1
Andriamanantena, D1
Carrère, C1
Casassus-Builhè, D1
Hamant, N1
Perret, JL1
Sandborn, WJ2
Stenson, WF1
Brynskov, J1
Lorenz, RG1
Steidle, GM1
Robbins, JL1
Kent, JD1
Bloom, BJ1
Bloomfeld, RS1
Okayama, M1
Hayashi, S1
Aoi, Y1
Nishio, H1
Kato, S1
Takeuchi, K1
Mahadevan, U1
Loftus, EV1
Tremaine, WJ1

Reviews

1 review available for celecoxib and Colitis Gravis

ArticleYear
Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease.
    The Cochrane database of systematic reviews, 2014, Oct-23, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis, Ulcerative; Crohn Disease; Cyclooxygena

2014

Trials

2 trials available for celecoxib and Colitis Gravis

ArticleYear
Safety of celecoxib in patients with ulcerative colitis in remission: a randomized, placebo-controlled, pilot study.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Colitis, Ulc

2006
Are COX-2 inhibitors safe for anyone.
    Inflammatory bowel diseases, 2006, Volume: 12, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis, Ulcerative; Cyclooxygenase 2 Inhibitors

2006

Other Studies

11 other studies available for celecoxib and Colitis Gravis

ArticleYear
Multisystem Autoimmune Inflammatory Disease, Including Colitis, Due to Inborn Error of Immunity.
    Pediatrics, 2021, Volume: 148, Issue:5

    Topics: Adolescent; Agammaglobulinemia; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Autoim

2021
Selenocoxib-3, a novel anti-inflammatory therapeutic effectively resolves colitis.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis; Coli

2023
Lipid-based nanocarrier-mediated targeted delivery of celecoxib attenuate severity of ulcerative colitis.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 116

    Topics: Animals; Celecoxib; Colitis, Ulcerative; Drug Carriers; Lipids; Mice; Nanostructures; Particle Size

2020
Fabrication and Evaluation of Celecoxib Oral Oleogel to Reduce the Inflammation of Ulcerative Colitis.
    AAPS PharmSciTech, 2021, Jun-15, Volume: 22, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis, Ulcerative; Colon; Dextran Sul

2021
Activation of NF-κB: bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2014, Volume: 68, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Celecoxib; Colitis, Ulcerative; Colonic Neoplasms; Cyclooxygenase 2

2014
pH-sensitive nanoparticles of curcumin-celecoxib combination: evaluating drug synergy in ulcerative colitis model.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:2

    Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Celecoxib; Co

2014
Celecoxib prevents colitis associated colon carcinogenesis: an upregulation of apoptosis.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:6

    Topics: Apoptosis; Celecoxib; Cell Cycle Checkpoints; Cell Proliferation; Colitis, Ulcerative; Colon; Coloni

2014
Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2011, Volume: 62, Issue:1

    Topics: Acetic Acid; Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Arginine; Benzoquinones; Celecoxib;

2011
[Ulcerating haemorrhagic colitis induced by celecoxib].
    Presse medicale (Paris, France : 1983), 2005, Mar-26, Volume: 34, Issue:6

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis, Ulcerative; Femal

2005
Aggravation by selective COX-1 and COX-2 inhibitors of dextran sulfate sodium (DSS)-induced colon lesions in rats.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:9

    Topics: Animals; Cardiovascular Diseases; Celecoxib; Colitis, Ulcerative; Colon; Cyclooxygenase 1; Cyclooxyg

2007
Safety of selective cyclooxygenase-2 inhibitors in inflammatory bowel disease.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:4

    Topics: Adult; Aged; Celecoxib; Colitis, Ulcerative; Crohn Disease; Cyclooxygenase 2; Cyclooxygenase 2 Inhib

2002