Page last updated: 2024-10-24

celecoxib and Cognition Disorders

celecoxib has been researched along with Cognition Disorders in 11 studies

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"We used data from the Alzheimer's Disease Anti-Inflammatory Prevention Trial to compare performance of a four-test Telephone Assessment Battery (TAB) that included the Telephone Interview for Cognitive Status (TICS) to that of a traditional in-person Cognitive Assessment Battery."2.78Screening by telephone in the Alzheimer's disease anti-inflammatory prevention trial. ( Brandt, J; Breitner, JC; Luis, CA; Martin, B; Reckess, GZ; Zandi, P, 2013)
"Celecoxib 200 mg bid did not slow the progression of AD in this study, and the occurrence of adverse events was as expected for an elderly population with a complex chronic medical condition."2.73Long-term efficacy and safety of celecoxib in Alzheimer's disease. ( Niculescu, L; Robbins, J; Soininen, H; West, C, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zolotovskaia, IA1
Davydkin, IL1
Reckess, GZ1
Brandt, J2
Luis, CA1
Zandi, P1
Martin, B1
Breitner, JC3
Tang, J1
Xiao, W1
Li, Q1
Deng, Q1
Chu, X1
Chen, Y1
Pan, D1
Fu, J1
Small, GW1
Siddarth, P1
Silverman, DH1
Ercoli, LM1
Miller, KJ1
Lavretsky, H1
Bookheimer, SY1
Huang, SC1
Barrio, JR1
Phelps, ME1
Meinert, CL1
McCaffrey, LD1
Borre, Y1
Lemstra, S1
Westphal, KG1
Morgan, ME1
Olivier, B1
Oosting, RS1
Casolini, P1
Catalani, A1
Zuena, AR1
Angelucci, L1
Melnikova, T1
Savonenko, A1
Wang, Q1
Liang, X1
Hand, T1
Wu, L1
Kaufmann, WE1
Vehmas, A1
Andreasson, KI1
Soininen, H1
West, C1
Robbins, J1
Niculescu, L1
Martin, BK1
Szekely, C1
Piantadosi, S1
Craft, S1
Evans, D1
Green, R1
Mullan, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)[NCT00007189]Phase 32,625 participants Interventional2001-01-31Completed
Alzheimer's Disease Anti-Inflammatory Prevention Trial Follow-Up Study[NCT01417130]1,650 participants (Anticipated)Observational2009-08-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for celecoxib and Cognition Disorders

ArticleYear
Results of a follow-up study to the randomized Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT).
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2013, Volume: 9, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents; Celecoxib; Cognit

2013
Screening by telephone in the Alzheimer's disease anti-inflammatory prevention trial.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Celecoxib; Cognition Disorders; Female; Geriatric Assess

2013
Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2008, Volume: 16, Issue:12

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Apolipoprotein

2008
Alzheimer's Disease Anti-inflammatory Prevention Trial: design, methods, and baseline results.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2009, Volume: 5, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Brain; Celecoxi

2009
Long-term efficacy and safety of celecoxib in Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2007, Volume: 23, Issue:1

    Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cognition Disorders; De

2007
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
    Archives of neurology, 2008, Volume: 65, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cogn

2008
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
    Archives of neurology, 2008, Volume: 65, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cogn

2008
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
    Archives of neurology, 2008, Volume: 65, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cogn

2008
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
    Archives of neurology, 2008, Volume: 65, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cogn

2008

Other Studies

5 other studies available for celecoxib and Cognition Disorders

ArticleYear
[Cognitive-cytokine effect of nonsteroidal antiinflammatory drugs in the therapy of elderly patients with osteoarthritis].
    Advances in gerontology = Uspekhi gerontologii, 2017, Volume: 30, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cognition; Cognition Disorders; Cytokines;

2017
A Cyclooxygenase-2 Inhibitor Reduces Vascular Wall Thickness and Ameliorates Cognitive Impairment in a Cerebral Small Vessel Diseases Rat Model.
    Current Alzheimer research, 2015, Volume: 12, Issue:7

    Topics: Animals; Brain; Celecoxib; Cerebral Small Vessel Diseases; Cognition Disorders; Collagen Type I; Cyc

2015
Celecoxib delays cognitive decline in an animal model of neurodegeneration.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: Analysis of Variance; Animals; Celecoxib; Cognition Disorders; Cyclooxygenase 2 Inhibitors; Cytokine

2012
Inhibition of COX-2 reduces the age-dependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat.
    Journal of neuroscience research, 2002, May-01, Volume: 68, Issue:3

    Topics: Aging; Animals; Celecoxib; Cognition Disorders; Corticosterone; Cyclooxygenase 2; Cyclooxygenase 2 I

2002
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern.
    Neuroscience, 2006, Sep-01, Volume: 141, Issue:3

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Behavior,

2006