celecoxib has been researched along with Chronic Pain in 19 studies
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether respectively radial extracoporeal shock wave therapy (rESWT) or a combination of rESWT, celecoxib and eperisone (rESWT + C + E) are superior in reducing pain in patients with chronic nonspecific low back pain (cnsLBP) compared to C + E alone (a standard treatment of this condition in China)." | 9.41 | Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial. ( Feng, Z; Guo, X; Li, L; Li, Y; Peng, Z; Schmitz, C; Yan, Z; Yang, Y; Zhang, Y, 2021) |
| "The aim of this study was to examine the cost-effectiveness of branded and authorized generic (AG) celecoxib for chronic pain patients with osteoarthritis (OA), rheumatoid arthritis (RA), and low back pain (LBP), using real-world cost information for loxoprofen and pharmacotherapy for gastrointestinal bleeding." | 8.02 | Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan. ( Kamae, I; Karasawa, Y; Murata, T; Nozawa, K; Sakamoto, C; Soen, S; Zeniya, S, 2021) |
| "Pregabalin in the context of multimodal pain management may be associated with reduced opioid consumption and other medical complications in patients undergoing TKA, including previous users of chronic pain medications." | 7.80 | Pregabalin reduces opioid consumption and improves outcome in chronic pain patients undergoing total knee arthroplasty. ( Chen, AF; Hozack, WJ; Parvizi, J; Sawan, H; Viscusi, ER, 2014) |
| "In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality of life (QOL)." | 7.30 | Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee. ( Aono, H; Endo, M; Hara, T; Kawahara, S; Kawano, T; Mawatari, T; Miyaji, T; Miyake, M; Nakashima, Y; Sakamoto, S; Sato, T; Shimokawa, M; Takano, T; Tokunaga, M; Zenda, S, 2023) |
| "Chronic low back pain is a common clinical problem in both the human and canine population." | 6.87 | Intradiscal application of a PCLA-PEG-PCLA hydrogel loaded with celecoxib for the treatment of back pain in canines: What's in it for humans? ( Beukers, M; Bos, C; Creemers, LB; de Leeuw, M; Grinwis, GCM; Meij, BP; Plomp, SGM; Tellegen, AR; Tryfonidou, MA; van Dijk, M; Willems, N, 2018) |
| " There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo." | 6.53 | Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016) |
| "Tramadol-acetaminophen was effective at reducing chronic LBP and conferred a prophylactic motivational effect in patients with chronic LBP." | 5.43 | Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain. ( Nishida, K; Ozaki, T; Takei, Y; Tanaka, M; Tetsunaga, T, 2016) |
| "To investigate whether respectively radial extracoporeal shock wave therapy (rESWT) or a combination of rESWT, celecoxib and eperisone (rESWT + C + E) are superior in reducing pain in patients with chronic nonspecific low back pain (cnsLBP) compared to C + E alone (a standard treatment of this condition in China)." | 5.41 | Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial. ( Feng, Z; Guo, X; Li, L; Li, Y; Peng, Z; Schmitz, C; Yan, Z; Yang, Y; Zhang, Y, 2021) |
| "Celecoxib is frequently prescribed to treat knee osteoarthritis (KOA), but how celecoxib influences the activity of the central nervous system to alleviate chronic pain remains unclear." | 5.30 | Cerebral mechanism of celecoxib for treating knee pain: study protocol for a randomized controlled parallel trial. ( Chen, Y; Cheng, S; Dong, X; He, W; Huang, Y; Li, Z; Liang, F; Sheng, Y; Tang, C; Wu, X; Yin, B; Zeng, F; Zhou, J, 2019) |
| "We know from adult randomised controlled trials that some NSAIDs, such as ibuprofen, naproxen, and aspirin, can be effective in certain chronic pain conditions." | 4.95 | Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. ( Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM, 2017) |
| "The aim of this study was to examine the cost-effectiveness of branded and authorized generic (AG) celecoxib for chronic pain patients with osteoarthritis (OA), rheumatoid arthritis (RA), and low back pain (LBP), using real-world cost information for loxoprofen and pharmacotherapy for gastrointestinal bleeding." | 4.02 | Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan. ( Kamae, I; Karasawa, Y; Murata, T; Nozawa, K; Sakamoto, C; Soen, S; Zeniya, S, 2021) |
| " Pelvic pain had developed in EAP rats, which was attenuated by a single treatment with celecoxib or pregabalin, suggesting that EAP is an appropriate model for prostatitis-related pain." | 3.88 | Chronic pelvic pain and prostate inflammation in rat experimental autoimmune prostatitis: Effect of a single treatment with phosphodiesterase 5 inhibitors on chronic pelvic pain. ( Kotera, T; Kurita, M; Oka, M; Okamoto, K; Yamaguchi, H, 2018) |
| "Pregabalin in the context of multimodal pain management may be associated with reduced opioid consumption and other medical complications in patients undergoing TKA, including previous users of chronic pain medications." | 3.80 | Pregabalin reduces opioid consumption and improves outcome in chronic pain patients undergoing total knee arthroplasty. ( Chen, AF; Hozack, WJ; Parvizi, J; Sawan, H; Viscusi, ER, 2014) |
| "In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality of life (QOL)." | 3.30 | Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee. ( Aono, H; Endo, M; Hara, T; Kawahara, S; Kawano, T; Mawatari, T; Miyaji, T; Miyake, M; Nakashima, Y; Sakamoto, S; Sato, T; Shimokawa, M; Takano, T; Tokunaga, M; Zenda, S, 2023) |
| "Chronic low back pain is a common clinical problem in both the human and canine population." | 2.87 | Intradiscal application of a PCLA-PEG-PCLA hydrogel loaded with celecoxib for the treatment of back pain in canines: What's in it for humans? ( Beukers, M; Bos, C; Creemers, LB; de Leeuw, M; Grinwis, GCM; Meij, BP; Plomp, SGM; Tellegen, AR; Tryfonidou, MA; van Dijk, M; Willems, N, 2018) |
| "Chronic pain is associated with impaired regulation of cardiovascular and analgesia systems, which may predispose to persistent BP elevation." | 2.82 | The Effects of Pain and Analgesic Medications on Blood Pressure. ( Coscarelli, A; Giordano, A; Menale, S; Rivasi, G; Turrin, G; Ungar, A, 2022) |
| " There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo." | 2.53 | Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016) |
| " For older adult patients at higher risk for NSAID-related adverse effects, such as those who have gastrointestinal or cardiovascular disease, diabetes mellitus, or who are taking low-dose aspirin, opioids are recommended instead." | 2.49 | Opioids for chronic pain: new evidence, new strategies, safe prescribing. ( de Leon-Casasola, OA, 2013) |
| "Tramadol-acetaminophen was effective at reducing chronic LBP and conferred a prophylactic motivational effect in patients with chronic LBP." | 1.43 | Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain. ( Nishida, K; Ozaki, T; Takei, Y; Tanaka, M; Tetsunaga, T, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 6 (31.58) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, X | 1 |
| Li, L | 1 |
| Yan, Z | 1 |
| Li, Y | 2 |
| Peng, Z | 1 |
| Yang, Y | 1 |
| Zhang, Y | 1 |
| Schmitz, C | 1 |
| Feng, Z | 1 |
| Rivasi, G | 1 |
| Menale, S | 1 |
| Turrin, G | 1 |
| Coscarelli, A | 1 |
| Giordano, A | 1 |
| Ungar, A | 1 |
| Xu, H | 1 |
| Zhao, C | 1 |
| Guo, G | 1 |
| A, X | 1 |
| Qiu, G | 1 |
| Wang, Y | 1 |
| Kang, B | 1 |
| Xu, X | 1 |
| Xie, J | 1 |
| Xiao, L | 1 |
| Antonen, EG | 1 |
| Kruchek, MM | 1 |
| Nikitina, MV | 1 |
| Endo, M | 1 |
| Kawahara, S | 1 |
| Sato, T | 1 |
| Tokunaga, M | 1 |
| Hara, T | 1 |
| Mawatari, T | 1 |
| Kawano, T | 1 |
| Zenda, S | 1 |
| Miyaji, T | 1 |
| Shimokawa, M | 1 |
| Sakamoto, S | 1 |
| Takano, T | 1 |
| Miyake, M | 1 |
| Aono, H | 1 |
| Nakashima, Y | 1 |
| Karasawa, Y | 1 |
| Kamae, I | 1 |
| Nozawa, K | 1 |
| Zeniya, S | 1 |
| Murata, T | 1 |
| Soen, S | 1 |
| Sakamoto, C | 1 |
| Tellegen, AR | 1 |
| Willems, N | 1 |
| Beukers, M | 1 |
| Grinwis, GCM | 1 |
| Plomp, SGM | 1 |
| Bos, C | 1 |
| van Dijk, M | 1 |
| de Leeuw, M | 1 |
| Creemers, LB | 1 |
| Tryfonidou, MA | 1 |
| Meij, BP | 1 |
| Eccleston, C | 1 |
| Cooper, TE | 1 |
| Fisher, E | 1 |
| Anderson, B | 1 |
| Wilkinson, NM | 1 |
| Kurita, M | 1 |
| Yamaguchi, H | 1 |
| Okamoto, K | 1 |
| Kotera, T | 1 |
| Oka, M | 1 |
| Tang, C | 1 |
| Dong, X | 1 |
| He, W | 1 |
| Cheng, S | 1 |
| Chen, Y | 1 |
| Huang, Y | 1 |
| Yin, B | 1 |
| Sheng, Y | 1 |
| Zhou, J | 1 |
| Wu, X | 1 |
| Zeng, F | 1 |
| Li, Z | 1 |
| Liang, F | 1 |
| Lee, JY | 2 |
| Choi, HY | 1 |
| Park, CS | 1 |
| Jang, C | 1 |
| Lee, KT | 1 |
| Youn, I | 1 |
| Yune, TY | 1 |
| de Leon-Casasola, OA | 1 |
| Sawan, H | 1 |
| Chen, AF | 1 |
| Viscusi, ER | 1 |
| Parvizi, J | 1 |
| Hozack, WJ | 1 |
| Danilov, AB | 1 |
| Grigorenko, NV | 1 |
| Laux-Biehlmann, A | 1 |
| Boyken, J | 1 |
| Dahllöf, H | 1 |
| Schmidt, N | 1 |
| Zollner, TM | 1 |
| Nagel, J | 1 |
| Xu, C | 1 |
| Gu, K | 1 |
| Yasen, Y | 1 |
| Hou, Y | 1 |
| Tetsunaga, T | 2 |
| Tanaka, M | 1 |
| Nishida, K | 1 |
| Takei, Y | 1 |
| Ozaki, T | 1 |
| Rastogi, R | 1 |
| Swarm, RA | 1 |
| Patel, TA | 1 |
| Robinson, I | 1 |
| Sargent, B | 1 |
| Hatcher, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized, Controlled, Single Centre Trial to Assess the Efficacy and Safety of Radial Extracorporeal Shock Wave Therapy in Patients With Chronic Non-specific Low Back Pain[NCT03337607] | 150 participants (Anticipated) | Interventional | 2017-11-13 | Recruiting | |||
| Comparative Effects of Shockwave Therapy and Maitland's Lumbar Mobilization on Pain, Disability and Range of Motion in Patients With Mechanical Low Back Pain[NCT05404997] | 26 participants (Anticipated) | Interventional | 2022-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for celecoxib and Chronic Pain
| Article | Year |
|---|---|
The Effects of Pain and Analgesic Medications on Blood Pressure.
Topics: Acetaminophen; Adrenergic Agents; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ster | 2022 |
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Asp | 2017 |
Opioids for chronic pain: new evidence, new strategies, safe prescribing.
Topics: Age Factors; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chronic Pain; C | 2013 |
[An antinociceptive effect of chondroprotectors: a myth or a reality?].
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; C-Reactive Protein; Celecoxib; Chondroitin Sulf | 2015 |
Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials.
Topics: Abdominal Pain; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Diarrhea; Dyspepsia; Headache; | 2016 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhi | 2011 |
5 trials available for celecoxib and Chronic Pain
8 other studies available for celecoxib and Chronic Pain
| Article | Year |
|---|---|
[Evaluation of the effectiveness of treatment of patients with nonspecific pain syndrome in the lower back with celecoxib and a combined preparation of B vitamins].
Topics: Adult; Celecoxib; Chronic Pain; Female; Humans; Low Back Pain; Male; Meloxicam; Middle Aged; Pain Me | 2022 |
Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan.
Topics: Aged; Aged, 80 and over; Celecoxib; Chronic Pain; Computer Simulation; Cost Savings; Cost-Benefit An | 2021 |
Chronic pelvic pain and prostate inflammation in rat experimental autoimmune prostatitis: Effect of a single treatment with phosphodiesterase 5 inhibitors on chronic pelvic pain.
Topics: Analgesics; Animals; Autoimmune Diseases; Celecoxib; Chemokines; Chronic Pain; Cytokines; Disease Mo | 2018 |
Inhibition of COX-2 alleviates lumbar spinal stenosis-induced chronic mechanical allodynia in rats.
Topics: Animals; Cauda Equina; Celecoxib; Chronic Pain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytok | 2019 |
Pregabalin reduces opioid consumption and improves outcome in chronic pain patients undergoing total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Chr | 2014 |
Dynamic weight bearing as a non-reflexive method for the measurement of abdominal pain in mice.
Topics: Abdominal Pain; Aniline Compounds; Animals; Behavior, Animal; Celecoxib; Chronic Pain; Cyclooxygenas | 2016 |
Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Apathy; | 2016 |
Use of dynamic weight bearing as a novel end-point for the assessment of Freund's Complete Adjuvant induced hypersensitivity in mice.
Topics: Adjuvants, Immunologic; Animals; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Endpoint Dete | 2012 |