celecoxib has been researched along with Cholangiocarcinoma in 9 studies
Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emodin, a tyrosine kinase inhibitor, effectively blocked tyrosine phosphorylation of p185(neu) overexpressed in cultured rat C611B cholangiocarcinoma (ChC) cells and in neu-transformed WB-F344 rat-liver epithelial stem-like cells (WBneu cells)." | 7.72 | Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3. ( Lai, GH; Sirica, AE; Zhang, Z, 2003) |
| "To evaluate the roles and mechanisms of celecoxib in inducing proliferation inhibition and apoptosis of human cholangiocarcinoma cell lines." | 7.72 | Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E2 pathway in human cholangiocarcinoma cell lines. ( Liu, ZR; Tang, ZH; Wang, JH; Wu, GS; Zou, SQ, 2003) |
| "Recently, we demonstrated that the cyclooxygenase-2 (COX-2) inhibitor celecoxib acts to significantly suppress the growth of rat C611B cholangiocarcinoma (ChC) cells in vitro." | 7.72 | Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation. ( Lai, GH; Sirica, AE; Zhang, Z, 2004) |
| "Celecoxib is an anti-inflammatory drug that induces intracellular ROS generation." | 5.39 | Synergistic effects of 5-aminolevulinic acid based photodynamic therapy and celecoxib via oxidative stress in human cholangiocarcinoma cells. ( Chung, CW; Jeong, YI; Kang, DH; Kim, CH; Kim, DH; Kwak, TW; Lee, HM, 2013) |
| "Emodin, a tyrosine kinase inhibitor, effectively blocked tyrosine phosphorylation of p185(neu) overexpressed in cultured rat C611B cholangiocarcinoma (ChC) cells and in neu-transformed WB-F344 rat-liver epithelial stem-like cells (WBneu cells)." | 3.72 | Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3. ( Lai, GH; Sirica, AE; Zhang, Z, 2003) |
| "To evaluate the roles and mechanisms of celecoxib in inducing proliferation inhibition and apoptosis of human cholangiocarcinoma cell lines." | 3.72 | Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E2 pathway in human cholangiocarcinoma cell lines. ( Liu, ZR; Tang, ZH; Wang, JH; Wu, GS; Zou, SQ, 2003) |
| "Recently, we demonstrated that the cyclooxygenase-2 (COX-2) inhibitor celecoxib acts to significantly suppress the growth of rat C611B cholangiocarcinoma (ChC) cells in vitro." | 3.72 | Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation. ( Lai, GH; Sirica, AE; Zhang, Z, 2004) |
| "Celecoxib is an anti-inflammatory drug that induces intracellular ROS generation." | 1.39 | Synergistic effects of 5-aminolevulinic acid based photodynamic therapy and celecoxib via oxidative stress in human cholangiocarcinoma cells. ( Chung, CW; Jeong, YI; Kang, DH; Kim, CH; Kim, DH; Kwak, TW; Lee, HM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CW | 1 |
| Yeh, CN | 2 |
| Chung, YH | 1 |
| Chen, YR | 1 |
| Tien, SW | 1 |
| Chen, TW | 1 |
| Farn, SS | 1 |
| Huang, YC | 1 |
| Yu, CS | 2 |
| Kim, CH | 1 |
| Chung, CW | 1 |
| Lee, HM | 1 |
| Kim, DH | 1 |
| Kwak, TW | 1 |
| Jeong, YI | 1 |
| Kang, DH | 1 |
| Chiang, KC | 1 |
| Juang, HH | 1 |
| S Pang, JH | 1 |
| Lin, KJ | 1 |
| Yeh, TS | 1 |
| Jan, YY | 1 |
| Lai, GH | 2 |
| Zhang, Z | 2 |
| Sirica, AE | 2 |
| Wu, GS | 1 |
| Zou, SQ | 1 |
| Liu, ZR | 1 |
| Tang, ZH | 1 |
| Wang, JH | 1 |
| Han, C | 2 |
| Leng, J | 2 |
| Demetris, AJ | 2 |
| Wu, T | 2 |
| Wu, G | 1 |
| Zou, S | 1 |
| Liu, Z | 1 |
| Qiu, F | 1 |
9 other studies available for celecoxib and Cholangiocarcinoma
| Article | Year |
|---|---|
Synthesis and evaluation of
Topics: Animals; Celecoxib; Cholangiocarcinoma; Cyclooxygenase 2; Dihydroxyphenylalanine; Disease Models, An | 2018 |
Synergistic effects of 5-aminolevulinic acid based photodynamic therapy and celecoxib via oxidative stress in human cholangiocarcinoma cells.
Topics: Aminolevulinic Acid; Analysis of Variance; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; C | 2013 |
Reappraisal of the therapeutic role of celecoxib in cholangiocarcinoma.
Topics: Animals; Apoptosis; Celecoxib; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cholang | 2013 |
Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, | 2003 |
Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E2 pathway in human cholangiocarcinoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Celecoxib; Cell Div | 2003 |
Cyclooxygenase-2 promotes human cholangiocarcinoma growth: evidence for cyclooxygenase-2-independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest.
Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Celecoxib; Cell Cycle; Cell Cycle Proteins; Cell Line | 2004 |
The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protei | 2004 |
Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bile Duct Neoplasms; Bile Duc | 2004 |
Effects of bile from patient with transduodenal sphincteroplasty on the growth of human cholangiocarcinoma cell line.
Topics: Antineoplastic Agents; Bile; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Celecoxib; Cell Division | 2004 |