Page last updated: 2024-10-24

celecoxib and Cardiovascular Abnormalities

celecoxib has been researched along with Cardiovascular Abnormalities in 1 studies

Cardiovascular Abnormalities: Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gong, L1
Thorn, CF1
Bertagnolli, MM1
Grosser, T1
Altman, RB1
Klein, TE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Control Trial Study of the Efficacy of Celecoxib Versus Ketorolac for Perioperative Pain Control[NCT03331315]Phase 2170 participants (Actual)Interventional2013-09-01Completed
Single Dose Oral Celecoxib (With or Without Acetaminophen) for Acute Post-operative Pain Following Impacted Third Molar Surgery.[NCT04790812]Phase 4100 participants (Anticipated)Interventional2021-04-22Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Average Inpatient Hydromorphone Use

Average inpatient hydromorphone use measured in milligrams (NCT03331315)
Timeframe: 48 hrs following surgery

InterventionMilligrams (Mean)
Ketorolac0.7
Celecoxib0.8

Average Inpatient Ondansetron Use

Average inpatient ondansetron use measured in milligrams (NCT03331315)
Timeframe: 48 hrs following surgery

InterventionMilligrams (Mean)
Ketorolac1.5
Celecoxib1.3

Average Inpatient Postoperative Pain Score

Pain measured using the Visual Analog Scale, no pain (0-0.4 cm), mild pain(0.5-4.4 cm), moderate pain (4.5-7.4 cm), and severe pain (7.5-10.0 cm). Subscale scoring was not used in analysis but provided as reference for patient and nursing staff. (NCT03331315)
Timeframe: 48 hrs following surgery

Interventionunits on a scale (Mean)
Ketorolac2.7
Celecoxib2.4

Days of Oral Narcotic Use After Discharge

Measured using postoperative questionnaire (NCT03331315)
Timeframe: 2 weeks after discharge

InterventionDays (Mean)
Ketorolac5.7
Celecoxib3.8

Number of Oral Narcotic Pills Used After Discharge

Number of oral narcotic pills used after discharge until 2 week postoperative visit. (NCT03331315)
Timeframe: 2 weeks after discharge

InterventionPills (Mean)
Ketorolac8.1
Celecoxib6.0

Number of Participants With Perioperative Complications

Perioperative Complications measured intraoperatively and postoperatively by type (NCT03331315)
Timeframe: During and after surgery

InterventionPatients (Number)
Ketorolac5
Celecoxib6

Return to Activities of Daily Living

Average number of days required for complete return to independent activities of daily living (NCT03331315)
Timeframe: 2 weeks after discharge

InterventionDays (Mean)
Ketorolac2.4
Celecoxib2.2

Total Hospital Stay

Total hospital stay from time fo admission to time of discharge measured in hours (NCT03331315)
Timeframe: Following surgery

InterventionHours (Mean)
Ketorolac11.6
Celecoxib11.9

Other Studies

1 other study available for celecoxib and Cardiovascular Abnormalities

ArticleYear
Celecoxib pathways: pharmacokinetics and pharmacodynamics.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological;

2012
Celecoxib pathways: pharmacokinetics and pharmacodynamics.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological;

2012
Celecoxib pathways: pharmacokinetics and pharmacodynamics.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological;

2012
Celecoxib pathways: pharmacokinetics and pharmacodynamics.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological;

2012