celecoxib has been researched along with Cardiomegaly in 5 studies
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the effects of celecoxib on pressure overload-induced cardiac hypertrophy (CH), cardiac dysfunction and explore the possible protective mechanisms." | 7.83 | Celecoxib prevents pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress. ( Hao, F; Kang, Y; Liu, Y; Si, M; Su, L; Wang, F; Wang, H; Xin, X; Xu, J; Xue, F; Xue, M; Yu, L; Zhang, C; Zhang, Y, 2016) |
| "To explore the effects of celecoxib on pressure overload-induced cardiac hypertrophy (CH), cardiac dysfunction and explore the possible protective mechanisms." | 3.83 | Celecoxib prevents pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress. ( Hao, F; Kang, Y; Liu, Y; Si, M; Su, L; Wang, F; Wang, H; Xin, X; Xu, J; Xue, F; Xue, M; Yu, L; Zhang, C; Zhang, Y, 2016) |
| "Further, it induced cardiac hypertrophy, detected in terms of greater heart weight index and cardiomyocyte cross-sectional area and produced interstitial and perivascular fibrosis." | 1.46 | Celecoxib aggravates cardiac apoptosis in L-NAME-induced pressure overload model in rats: Immunohistochemical determination of cardiac caspase-3, Mcl-1, Bax and Bcl-2. ( Abo-Elmatty, DM; El-Baz, AA; Ibrahim, A; Mosaad, SM; Moustafa, YM; Zaitone, SA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, Z | 1 |
| Wang, S | 1 |
| Liang, Z | 1 |
| Zeng, L | 1 |
| Lai, R | 1 |
| Ye, Z | 1 |
| Liao, P | 1 |
| Mosaad, SM | 1 |
| Zaitone, SA | 1 |
| Ibrahim, A | 1 |
| El-Baz, AA | 1 |
| Abo-Elmatty, DM | 1 |
| Moustafa, YM | 1 |
| Li, H | 1 |
| Gao, S | 1 |
| Ye, J | 1 |
| Feng, X | 1 |
| Cai, Y | 1 |
| Liu, Z | 1 |
| Lu, J | 1 |
| Li, Q | 1 |
| Huang, X | 1 |
| Chen, S | 1 |
| Liu, P | 1 |
| Zhang, C | 1 |
| Wang, F | 1 |
| Zhang, Y | 1 |
| Kang, Y | 1 |
| Wang, H | 1 |
| Si, M | 1 |
| Su, L | 1 |
| Xin, X | 1 |
| Xue, F | 1 |
| Hao, F | 1 |
| Yu, L | 1 |
| Xu, J | 1 |
| Liu, Y | 1 |
| Xue, M | 1 |
| Wang, BH | 1 |
| Bertucci, MC | 1 |
| Ma, JY | 1 |
| Adrahtas, A | 1 |
| Cheung, RY | 1 |
| Krum, H | 1 |
5 other studies available for celecoxib and Cardiomegaly
| Article | Year |
|---|---|
Impacts of a Specific Cyclooxygenase-2 Inhibitor on Pressure Overload-Induced Myocardial Hypertrophy in Rats.
Topics: Animals; C-Reactive Protein; Cardiomegaly; Celecoxib; Cyclooxygenase 2 Inhibitors; Diet; Dinoproston | 2019 |
Celecoxib aggravates cardiac apoptosis in L-NAME-induced pressure overload model in rats: Immunohistochemical determination of cardiac caspase-3, Mcl-1, Bax and Bcl-2.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Cardiomegaly; Caspase 3; Celecoxib; | 2017 |
COX-2 is involved in ET-1-induced hypertrophy of neonatal rat cardiomyocytes: role of NFATc3.
Topics: Animals; Animals, Newborn; Calcineurin; Cardiomegaly; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 | 2014 |
Celecoxib prevents pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress.
Topics: Animals; Apoptosis; Cardiomegaly; Cardiotonic Agents; Celecoxib; Cell Survival; Cyclooxygenase 2 Inh | 2016 |
Celecoxib, but not rofecoxib or naproxen, attenuates cardiac hypertrophy and fibrosis induced in vitro by angiotensin and aldosterone.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Car | 2010 |