celecoxib has been researched along with Cardiac Hypertrophy in 5 studies
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the effects of celecoxib on pressure overload-induced cardiac hypertrophy (CH), cardiac dysfunction and explore the possible protective mechanisms." | 7.83 | Celecoxib prevents pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress. ( Hao, F; Kang, Y; Liu, Y; Si, M; Su, L; Wang, F; Wang, H; Xin, X; Xu, J; Xue, F; Xue, M; Yu, L; Zhang, C; Zhang, Y, 2016) |
| "To explore the effects of celecoxib on pressure overload-induced cardiac hypertrophy (CH), cardiac dysfunction and explore the possible protective mechanisms." | 3.83 | Celecoxib prevents pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress. ( Hao, F; Kang, Y; Liu, Y; Si, M; Su, L; Wang, F; Wang, H; Xin, X; Xu, J; Xue, F; Xue, M; Yu, L; Zhang, C; Zhang, Y, 2016) |
| "Further, it induced cardiac hypertrophy, detected in terms of greater heart weight index and cardiomyocyte cross-sectional area and produced interstitial and perivascular fibrosis." | 1.46 | Celecoxib aggravates cardiac apoptosis in L-NAME-induced pressure overload model in rats: Immunohistochemical determination of cardiac caspase-3, Mcl-1, Bax and Bcl-2. ( Abo-Elmatty, DM; El-Baz, AA; Ibrahim, A; Mosaad, SM; Moustafa, YM; Zaitone, SA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, Z | 1 |
| Wang, S | 1 |
| Liang, Z | 1 |
| Zeng, L | 1 |
| Lai, R | 1 |
| Ye, Z | 1 |
| Liao, P | 1 |
| Mosaad, SM | 1 |
| Zaitone, SA | 1 |
| Ibrahim, A | 1 |
| El-Baz, AA | 1 |
| Abo-Elmatty, DM | 1 |
| Moustafa, YM | 1 |
| Li, H | 1 |
| Gao, S | 1 |
| Ye, J | 1 |
| Feng, X | 1 |
| Cai, Y | 1 |
| Liu, Z | 1 |
| Lu, J | 1 |
| Li, Q | 1 |
| Huang, X | 1 |
| Chen, S | 1 |
| Liu, P | 1 |
| Zhang, C | 1 |
| Wang, F | 1 |
| Zhang, Y | 1 |
| Kang, Y | 1 |
| Wang, H | 1 |
| Si, M | 1 |
| Su, L | 1 |
| Xin, X | 1 |
| Xue, F | 1 |
| Hao, F | 1 |
| Yu, L | 1 |
| Xu, J | 1 |
| Liu, Y | 1 |
| Xue, M | 1 |
| Wang, BH | 1 |
| Bertucci, MC | 1 |
| Ma, JY | 1 |
| Adrahtas, A | 1 |
| Cheung, RY | 1 |
| Krum, H | 1 |
5 other studies available for celecoxib and Cardiac Hypertrophy
| Article | Year |
|---|---|
Impacts of a Specific Cyclooxygenase-2 Inhibitor on Pressure Overload-Induced Myocardial Hypertrophy in Rats.
Topics: Animals; C-Reactive Protein; Cardiomegaly; Celecoxib; Cyclooxygenase 2 Inhibitors; Diet; Dinoproston | 2019 |
Celecoxib aggravates cardiac apoptosis in L-NAME-induced pressure overload model in rats: Immunohistochemical determination of cardiac caspase-3, Mcl-1, Bax and Bcl-2.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Cardiomegaly; Caspase 3; Celecoxib; | 2017 |
COX-2 is involved in ET-1-induced hypertrophy of neonatal rat cardiomyocytes: role of NFATc3.
Topics: Animals; Animals, Newborn; Calcineurin; Cardiomegaly; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 | 2014 |
Celecoxib prevents pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress.
Topics: Animals; Apoptosis; Cardiomegaly; Cardiotonic Agents; Celecoxib; Cell Survival; Cyclooxygenase 2 Inh | 2016 |
Celecoxib, but not rofecoxib or naproxen, attenuates cardiac hypertrophy and fibrosis induced in vitro by angiotensin and aldosterone.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Car | 2010 |