Page last updated: 2024-10-24

celecoxib and Carcinoma

celecoxib has been researched along with Carcinoma in 26 studies

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"To investigate the synergistic cytotoxicity of cis-dichlorodiamine platinum (DDP) and celecoxib on nasopharyngeal carcinoma TW03 cell which is resistant to DDP (TW03/DDP)."7.81[Combined application of cisplatin and celecoxib inhibits the proliferation and promotes apoptosis of nasopharyngeal carcinoma cells resistant to cisplatin]. ( Chen, J; Li, Q; Liu, S; Peng, J, 2015)
"The cell colony formation assay after the combination of celecoxib and radiation treatment was done on C666-1, CNE-1 and CNE-2 nasopharyngeal carcinoma cells, which expressed different COX-2 levels."7.80Celecoxib enhances radiosensitivity via induction of G₂-M phase arrest and apoptosis in nasopharyngeal carcinoma. ( Chen, WB; Huang, B; Liang, CH; Qiu, QH; Zhang, SX, 2014)
"To investigate the mechanisms underlying the anticancer effect of celecoxib on nasopharyngeal carcinoma (NPC)."7.78Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. ( Hu, GQ; Hu, GY; Liu, DB; Long, GX; Mei, Q; Qiu, H, 2012)
"The aim of the study is to determine the effect of Celecoxib administration, dietary or topical, on expression of Ki-67, c-erb-B2, bcl-2 and bax genes in rat tongue by the immunohistochemistry methods and also tdt-mediated dupt-biotin nick end labeling assay in order to explore their role in malignant transformation and the proliferation rate, apoptosis rate in tongue squamous cell carcinoma."7.75Effect of dietary and topical Celecoxib on expression of bcl-2, bax, c-erb-B2 and Ki67 in carcinogen-induced tongue carcinoma in rat. ( Abbasi, MM; Aydemir, I; Dustar, Y; Javadzadeh, BY; Kalati, FA; Khaki, AA; Rad, JS; Roshangar, L; Sohrabi, M; Tuglu, IM; Vatansever, S, 2009)
"This study was performed to evaluate whether down-regulation of prostaglandin E(2) (PGE(2)) synthesis by celecoxib treatment is associated with inhibition of cell growth in human colon carcinoma cell lines."7.74Down-regulation of PGE2 by physiologic levels of celecoxib is not sufficient to induce apoptosis or inhibit cell proliferation in human colon carcinoma cell lines. ( Arber, N; Ben-Yosef, R; Kazanov, D; Lev-Ari, S; Liberman, E, 2007)
"To evaluate the role of celecoxib on 15-lipoxygenase-1 (15-LOX-1) expression, protein levels, and rates of apoptosis in colorectal cancer cell lines."7.73Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. ( Arnoletti, JP; Bland, KI; Boedefeld, W; Frolov, A; Hawkins, A; Heslin, MJ; Soong, R; Urist, MM, 2005)
"Local recurrence in colon cancer causes poor prognosis affecting overall survival of cancer-affected patient population."5.43Cooperative effect of BI-69A11 and celecoxib enhances radiosensitization by modulating DNA damage repair in colon carcinoma. ( Chaurasia, M; Chowdhury, T; Das, S; Dey, KK; Mandal, M; Pal, I; Parida, S; Rajesh, Y; Sharma, K, 2016)
"Celecoxib is a selective inhibitor of COX-2, whose connection with the development and progression of human tumors has been extensively studied."5.40Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity. ( Gan, L; Hu, GQ; Hu, GY; Jiang, JZ; Li, WW; Liu, DB; Long, GX; Mei, Q; Sun, W; Wang, JF, 2014)
"Colorectal carcinomas are well known to highly express COX-2 and their growth is markedly inhibited by COX-2 inhibitors, but little is known about head and neck carcinomas."5.32Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines. ( Hashitani, S; Maeda, T; Nishimura, N; Noguchi, K; Sakurai, K; Takaoka, K; Urade, M, 2003)
"To investigate the synergistic cytotoxicity of cis-dichlorodiamine platinum (DDP) and celecoxib on nasopharyngeal carcinoma TW03 cell which is resistant to DDP (TW03/DDP)."3.81[Combined application of cisplatin and celecoxib inhibits the proliferation and promotes apoptosis of nasopharyngeal carcinoma cells resistant to cisplatin]. ( Chen, J; Li, Q; Liu, S; Peng, J, 2015)
"The cell colony formation assay after the combination of celecoxib and radiation treatment was done on C666-1, CNE-1 and CNE-2 nasopharyngeal carcinoma cells, which expressed different COX-2 levels."3.80Celecoxib enhances radiosensitivity via induction of G₂-M phase arrest and apoptosis in nasopharyngeal carcinoma. ( Chen, WB; Huang, B; Liang, CH; Qiu, QH; Zhang, SX, 2014)
"To investigate the mechanisms underlying the anticancer effect of celecoxib on nasopharyngeal carcinoma (NPC)."3.78Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. ( Hu, GQ; Hu, GY; Liu, DB; Long, GX; Mei, Q; Qiu, H, 2012)
"Celecoxib combined with radiotherapy could induce apoptosis and enhance the radiosensitivity of human nasopharyngeal carcinoma CNE-2Z cell lines."3.77[Effects of celecoxib combined with radiotherapy on apoptosis of CNE-2Z cell lines]. ( Gui, P; Peng, P; Wei, LZ; Xiang, YZ; Xiong, ZJ; Yu, L, 2011)
"The aim of the study is to determine the effect of Celecoxib administration, dietary or topical, on expression of Ki-67, c-erb-B2, bcl-2 and bax genes in rat tongue by the immunohistochemistry methods and also tdt-mediated dupt-biotin nick end labeling assay in order to explore their role in malignant transformation and the proliferation rate, apoptosis rate in tongue squamous cell carcinoma."3.75Effect of dietary and topical Celecoxib on expression of bcl-2, bax, c-erb-B2 and Ki67 in carcinogen-induced tongue carcinoma in rat. ( Abbasi, MM; Aydemir, I; Dustar, Y; Javadzadeh, BY; Kalati, FA; Khaki, AA; Rad, JS; Roshangar, L; Sohrabi, M; Tuglu, IM; Vatansever, S, 2009)
"This study was performed to evaluate whether down-regulation of prostaglandin E(2) (PGE(2)) synthesis by celecoxib treatment is associated with inhibition of cell growth in human colon carcinoma cell lines."3.74Down-regulation of PGE2 by physiologic levels of celecoxib is not sufficient to induce apoptosis or inhibit cell proliferation in human colon carcinoma cell lines. ( Arber, N; Ben-Yosef, R; Kazanov, D; Lev-Ari, S; Liberman, E, 2007)
"To evaluate the role of celecoxib on 15-lipoxygenase-1 (15-LOX-1) expression, protein levels, and rates of apoptosis in colorectal cancer cell lines."3.73Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. ( Arnoletti, JP; Bland, KI; Boedefeld, W; Frolov, A; Hawkins, A; Heslin, MJ; Soong, R; Urist, MM, 2005)
"Local recurrence in colon cancer causes poor prognosis affecting overall survival of cancer-affected patient population."1.43Cooperative effect of BI-69A11 and celecoxib enhances radiosensitization by modulating DNA damage repair in colon carcinoma. ( Chaurasia, M; Chowdhury, T; Das, S; Dey, KK; Mandal, M; Pal, I; Parida, S; Rajesh, Y; Sharma, K, 2016)
"Celecoxib is a selective inhibitor of COX-2, whose connection with the development and progression of human tumors has been extensively studied."1.40Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity. ( Gan, L; Hu, GQ; Hu, GY; Jiang, JZ; Li, WW; Liu, DB; Long, GX; Mei, Q; Sun, W; Wang, JF, 2014)
"The underlying causes of endometrial cancer (EMC) are poorly understood, and treatment options for patients with advanced stages of the disease are limited."1.40Mammalian target of rapamycin complex 1 and cyclooxygenase 2 pathways cooperatively exacerbate endometrial cancer. ( Cappelletti, M; Daikoku, T; Dey, SK; Ellenson, LH; Hossain, MM; Terakawa, J; Yang, P; Yoshie, M, 2014)
"Colorectal carcinomas are well known to highly express COX-2 and their growth is markedly inhibited by COX-2 inhibitors, but little is known about head and neck carcinomas."1.32Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines. ( Hashitani, S; Maeda, T; Nishimura, N; Noguchi, K; Sakurai, K; Takaoka, K; Urade, M, 2003)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (50.00)29.6817
2010's12 (46.15)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Imaduddin, M1
Sultania, M1
Vigneshwaran, B1
Muduly, DK1
Kar, M1
Hauser, P1
Vancsó, I1
Pócza, T1
Schuler, D1
Garami, M1
Li, WW1
Long, GX2
Liu, DB2
Mei, Q2
Wang, JF1
Hu, GY2
Jiang, JZ1
Sun, W1
Gan, L1
Hu, GQ2
Zhang, SX1
Qiu, QH1
Chen, WB1
Liang, CH1
Huang, B1
Daikoku, T1
Terakawa, J1
Hossain, MM1
Yoshie, M1
Cappelletti, M1
Yang, P2
Ellenson, LH1
Dey, SK1
Chen, J1
Liu, S1
Li, Q1
Peng, J1
Pal, I1
Dey, KK1
Chaurasia, M1
Parida, S1
Das, S1
Rajesh, Y1
Sharma, K1
Chowdhury, T1
Mandal, M1
Brown, PH1
Subbaramaiah, K1
Salmon, AP1
Baker, R1
Newman, RA1
Zhou, XK1
Bissonnette, RP1
Dannenberg, AJ1
Howe, LR1
Grushka, JR1
Ryckman, J1
Mueller, C1
Roessingh, Ade B1
Walton, JM1
St Vil, D1
Laberge, JM1
Bernard, C1
Nguyen, VH1
Puligandla, PS1
Sohrabi, M1
Kalati, FA1
Vatansever, S1
Abbasi, MM1
Roshangar, L1
Khaki, AA1
Tuglu, IM1
Aydemir, I1
Dustar, Y1
Javadzadeh, BY1
Rad, JS1
Bidard, FC1
Mathiot, C1
Delaloge, S1
Brain, E1
Giachetti, S1
de Cremoux, P1
Marty, M1
Pierga, JY1
Bocca, C1
Bozzo, F1
Bassignana, A1
Miglietta, A1
Xiang, YZ1
Wei, LZ1
Yu, L1
Gui, P1
Peng, P1
Xiong, ZJ1
Qiu, H1
Lönnroth, C1
Andersson, M1
Nordgren, S1
Lundholm, K1
Lasalvia-Prisco, E1
Goldschmidt, P1
Galmarini, F1
Cucchi, S1
Vázquez, J1
Aghazarian, M1
Lasalvia-Galante, E1
Golomar, W1
Gordon, W1
Hashitani, S1
Urade, M1
Nishimura, N1
Maeda, T1
Takaoka, K1
Noguchi, K1
Sakurai, K1
Davis, TW1
O'Neal, JM1
Pagel, MD1
Zweifel, BS1
Mehta, PP1
Heuvelman, DM1
Masferrer, JL1
Roh, JL1
Sung, MW1
Kim, KH1
Heslin, MJ1
Hawkins, A1
Boedefeld, W1
Arnoletti, JP1
Frolov, A1
Soong, R1
Urist, MM1
Bland, KI1
Maiello, E1
Gebbia, V1
Giuliani, F1
Paoletti, G1
Gebbia, N1
Borsellino, N1
Cartenì, G1
Pezzella, G1
Manzione, L1
Romito, S1
Lopez, M1
Colucci, G1
Tsutsumi, S1
Namba, T1
Tanaka, KI1
Arai, Y1
Ishihara, T1
Aburaya, M1
Mima, S1
Hoshino, T1
Mizushima, T1
Casanova, I1
Parreño, M1
Farré, L1
Guerrero, S1
Céspedes, MV1
Pavon, MA1
Sancho, FJ1
Marcuello, E1
Trias, M1
Mangues, R1
Raskov, HH1
Lev-Ari, S1
Kazanov, D1
Liberman, E1
Ben-Yosef, R1
Arber, N1
Riedel, SB1
Fischer, SM1
Sanders, BG1
Kline, K1

Reviews

2 reviews available for celecoxib and Carcinoma

ArticleYear
Spindle epithelial tumor with thymus-like elements of the thyroid: a multi-institutional case series and review of the literature.
    Journal of pediatric surgery, 2009, Volume: 44, Issue:5

    Topics: Abscess; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma; Celecoxib; Ch

2009
[Non-steroidal anti-inflammatory agents and prevention of colorectal adenomas and carcinomas].
    Ugeskrift for laeger, 2006, Jan-23, Volume: 168, Issue:4

    Topics: Adenoma; Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents;

2006

Trials

3 trials available for celecoxib and Carcinoma

ArticleYear
Single circulating tumor cell detection and overall survival in nonmetastatic breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Addition of an induction regimen of antiangiogenesis and antitumor immunity to standard chemotherapy improves survival in advanced malignancies.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:5

    Topics: Acetylcysteine; Angiogenesis Inhibitors; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma; Carci

2012
FOLFIRI regimen in advanced colorectal cancer: the experience of the Gruppo Oncologico dell'Italia Meridionale (GOIM).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16 Suppl 4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Celecoxib; Col

2005

Other Studies

21 other studies available for celecoxib and Carcinoma

ArticleYear
Metronomic therapy using Methotrexate and Celecoxib: A Boon for Oral Cancer patients during COVID-19 Pandemic.
    Oral oncology, 2021, Volume: 114

    Topics: Carcinoma; Celecoxib; Cisplatin; COVID-19; Humans; Methotrexate; Mouth Neoplasms; Neoplasm Recurrenc

2021
[Antiangiogenic treatment of pediatric CNS tumors in Hungary with the Kieran schedule].
    Magyar onkologia, 2013, Volume: 57, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemothera

2013
Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity.
    Die Pharmazie, 2014, Volume: 69, Issue:2

    Topics: Carcinoma; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coloring Agents; Cyclooxy

2014
Celecoxib enhances radiosensitivity via induction of G₂-M phase arrest and apoptosis in nasopharyngeal carcinoma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2014, Volume: 33, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Celecoxib; Cell Cycle Checkpoints; Cell Division; Cell

2014
Mammalian target of rapamycin complex 1 and cyclooxygenase 2 pathways cooperatively exacerbate endometrial cancer.
    The American journal of pathology, 2014, Volume: 184, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Carcinoma; Celecoxib; Cell Line,

2014
[Combined application of cisplatin and celecoxib inhibits the proliferation and promotes apoptosis of nasopharyngeal carcinoma cells resistant to cisplatin].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2015, Volume: 31, Issue:2

    Topics: Antineoplastic Agents; Carcinoma; Celecoxib; Cell Proliferation; Cisplatin; Drug Resistance, Neoplas

2015
Cooperative effect of BI-69A11 and celecoxib enhances radiosensitization by modulating DNA damage repair in colon carcinoma.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:5

    Topics: Apoptosis; Benzimidazoles; Carcinoma; Celecoxib; Colonic Neoplasms; Combined Modality Therapy; DNA B

2016
Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Carcinoma; Celecoxib; Cell Tran

2008
Effect of dietary and topical Celecoxib on expression of bcl-2, bax, c-erb-B2 and Ki67 in carcinogen-induced tongue carcinoma in rat.
    Pakistan journal of biological sciences : PJBS, 2009, May-15, Volume: 12, Issue:10

    Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; bcl-2-Associated X Protein; Carcinoge

2009
Antiproliferative effects of COX-2 inhibitor celecoxib on human breast cancer cell lines.
    Molecular and cellular biochemistry, 2011, Volume: 350, Issue:1-2

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Celecoxib; Cell Adhesion; Cell Line, Tumor; Cell

2011
[Effects of celecoxib combined with radiotherapy on apoptosis of CNE-2Z cell lines].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2011, Volume: 46, Issue:7

    Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma; Caspase 3; Celecoxib; Cell Line, Tumor; Humans; Na

2011
Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma; Celecoxib; Cell Cycle Checkpoints; C

2012
Downregulation of Prominin 1/CD133 expression in colorectal cancer by NSAIDs following short-term preoperative treatment.
    International journal of oncology, 2012, Volume: 41, Issue:1

    Topics: AC133 Antigen; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Bioma

2012
Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines.
    International journal of oncology, 2003, Volume: 23, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Bl

2003
Synergy between celecoxib and radiotherapy results from inhibition of cyclooxygenase-2-derived prostaglandin E2, a survival factor for tumor and associated vasculature.
    Cancer research, 2004, Jan-01, Volume: 64, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma; Celecoxib; Colonic Neoplasms; Combined Modality Therapy;

2004
Suppression of accelerated tumor growth in surgical wounds by celecoxib and indomethacin.
    Head & neck, 2005, Volume: 27, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma; Carcinoma, Squamous Cell; Celecoxib; Ce

2005
Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer.
    Annals of surgery, 2005, Volume: 241, Issue:6

    Topics: Adenoma; Apoptosis; Arachidonate 15-Lipoxygenase; Blotting, Western; Carcinoma; Celecoxib; Colorecta

2005
Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells.
    Oncogene, 2006, Feb-16, Volume: 25, Issue:7

    Topics: Activating Transcription Factor 4; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Calc

2006
Celecoxib induces anoikis in human colon carcinoma cells associated with the deregulation of focal adhesions and nuclear translocation of p130Cas.
    International journal of cancer, 2006, May-15, Volume: 118, Issue:10

    Topics: Anoikis; Carcinoma; Celecoxib; Cell Nucleus; Colonic Neoplasms; Crk-Associated Substrate Protein; Cy

2006
Down-regulation of PGE2 by physiologic levels of celecoxib is not sufficient to induce apoptosis or inhibit cell proliferation in human colon carcinoma cell lines.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Carcinoma; Celecoxib; Cel

2007
Vitamin E analog, alpha-tocopherol ether-linked acetic acid analog, alone and in combination with celecoxib, reduces multiplicity of ultraviolet-induced skin cancers in mice.
    Anti-cancer drugs, 2008, Volume: 19, Issue:2

    Topics: Acetates; Administration, Inhalation; Animals; Antineoplastic Combined Chemotherapy Protocols; Carci

2008