Page last updated: 2024-10-24

celecoxib and Carcinoma, Basal Cell

celecoxib has been researched along with Carcinoma, Basal Cell in 8 studies

Carcinoma, Basal Cell: A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)

Research Excerpts

ExcerptRelevanceReference
" We then assessed the effects of celecoxib on the development of BCCs in a 3-year, double-blinded, randomized clinical trial in 60 (PTCH1(+/-)) patients with the basal cell nevus syndrome."5.14Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice. ( Aszterbaum, M; Athar, M; Barsanti, F; Bickers, DR; Cappola, C; Epstein, EH; Estevez, N; Hebert, J; Hwang, J; Khaimskiy, Y; Kim, A; Kohn, MA; Kopelovich, L; Lu, Y; McCulloch, CE; So, PL; Tang, JY; Tang, X, 2010)
"CDH11 expressing basal-like breast carcinomas and other CDH11 expressing malignancies exhibit poor prognosis."1.40Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. ( Anastasiadis, PZ; Assefnia, S; Brenner, M; Brown, ML; Byers, SW; Dakshanamurthy, S; Foley, DW; Guidry Auvil, JM; Haigh, D; Hampel, C; Kallakury, B; Shapiro, L; Uren, A, 2014)
" Neither association was observed when stratified by NSAID type (aspirin and other NSAIDs), nor did dose-response patterns emerge by frequency of use (average days per month)."1.38Use of nonsteroidal anti-inflammatory drugs and risk of basal cell carcinoma in the United States Radiologic Technologists study. ( Alexander, BH; Cahoon, EK; Doody, MM; Freedman, DM; Linet, MS; Rajaraman, P, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Assefnia, S1
Dakshanamurthy, S1
Guidry Auvil, JM1
Hampel, C1
Anastasiadis, PZ1
Kallakury, B1
Uren, A1
Foley, DW1
Brown, ML1
Shapiro, L1
Brenner, M1
Haigh, D1
Byers, SW1
Tang, JY1
Aszterbaum, M1
Athar, M1
Barsanti, F1
Cappola, C1
Estevez, N1
Hebert, J1
Hwang, J1
Khaimskiy, Y1
Kim, A1
Lu, Y1
So, PL1
Tang, X1
Kohn, MA1
McCulloch, CE1
Kopelovich, L1
Bickers, DR1
Epstein, EH1
Meyskens, FL1
McLaren, CE1
Elmets, CA1
Viner, JL1
Pentland, AP1
Cantrell, W1
Lin, HY1
Bailey, H1
Kang, S1
Linden, KG1
Heffernan, M1
Duvic, M1
Richmond, E1
Elewski, BE1
Umar, A1
Bell, W1
Gordon, GB1
Cahoon, EK1
Rajaraman, P1
Alexander, BH1
Doody, MM1
Linet, MS1
Freedman, DM1
Liebman, TN1
Stein, JA1
Polsky, D1
Wilgus, TA1
Koki, AT1
Zweifel, BS1
Kusewitt, DF1
Rubal, PA1
Oberyszyn, TM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II/III Randomized, Double-Blind, Placebo-Controlled Clinical Trial Of Celecoxib In Subjects With Actinic Keratoses[NCT00027976]Phase 2/Phase 30 participants (Actual)Interventional2001-12-31Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for celecoxib and Carcinoma, Basal Cell

ArticleYear
Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell;

2010
Celecoxib may decrease some skin cancers.
    The Nurse practitioner, 2010, Volume: 35, Issue:6

    Topics: Animals; Carcinoma, Basal Cell; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Mice; Pyrazoles; Ski

2010
Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial.
    Journal of the National Cancer Institute, 2010, Dec-15, Volume: 102, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Carcinoma, Basal Cell; Carcinoma, Squamous

2010

Other Studies

5 other studies available for celecoxib and Carcinoma, Basal Cell

ArticleYear
Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies.
    Oncotarget, 2014, Mar-30, Volume: 5, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Arthritis, Rheumatoid; Blotting, Western; Breast Neoplas

2014
Chemoprevention, risk reduction, therapeutic prevention, or preventive therapy?
    Journal of the National Cancer Institute, 2010, Dec-15, Volume: 102, Issue:24

    Topics: Adenoma; Anticarcinogenic Agents; Breast Neoplasms; Carcinoma, Basal Cell; Carcinoma, Squamous Cell;

2010
Use of nonsteroidal anti-inflammatory drugs and risk of basal cell carcinoma in the United States Radiologic Technologists study.
    International journal of cancer, 2012, Jun-15, Volume: 130, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Basal Cell; Cele

2012
Cyclo-oxygenase-2 inhibitors for chemoprevention of nonmelanoma skin cancer: is there a role for these agents?
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:1

    Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Celecoxib; Cyclooxygenase 2 Inhibitors; Cy

2013
Inhibition of cutaneous ultraviolet light B-mediated inflammation and tumor formation with topical celecoxib treatment.
    Molecular carcinogenesis, 2003, Volume: 38, Issue:2

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents;

2003