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celecoxib and Cancer of Rectum

celecoxib has been researched along with Cancer of Rectum in 7 studies

Research Excerpts

ExcerptRelevanceReference
"With a lower efficacy than Sou-Medrol in decreasing postoperative inflammation, celecoxib produces a better effect in inhibiting COX-2 expression, but it does not lower postoperative recurrence rate of rectal cancer."5.20[Perioperative immunomodulatory therapy does not decrease postoperative recurrence rate of rectal cancer]. ( Gan, ZM; Li, L; Liu, D; Lv, DH; Wang, XD, 2015)
"Patients with clinical stage II or III rectal cancer were treated with radiotherapy of 44 Gy in 22 fractions."2.79Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study. ( Chen, HC; Chen, HH; Chen, WT; Chien, CR; Hsiao, CF; Lee, HH; Lin, TC; Lin, TY; Liu, TW; Wang, LW, 2014)
"Celecoxib dosage was fixed."2.75A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer. ( Alqaisi, M; Bernal, P; Bush, D; Byrd, J; Garberoglio, C; Hussein, F; Malik, I, 2010)
"Some rectal cancers respond well to preoperative neoadjuvant therapy while others are inherently resistant or develop resistance during the treatment."2.72Molecular responses of rectal cancer to preoperative chemoradiation. ( Debucquoy, A; Geboes, K; Goethals, L; Haustermans, K; Mc Bride, WH; Roels, S, 2006)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, LW1
Hsiao, CF1
Chen, WT1
Lee, HH1
Lin, TC1
Chen, HC1
Chen, HH1
Chien, CR1
Lin, TY1
Liu, TW1
Gan, ZM1
Wang, XD1
Lv, DH1
Liu, D1
Li, L1
Debucquoy, A2
Roels, S2
Goethals, L2
Libbrecht, L1
Van Cutsem, E1
Geboes, K2
Penninckx, F1
D'Hoore, A1
McBride, WH1
Haustermans, K2
Malik, I1
Hussein, F1
Bush, D1
Alqaisi, M1
Bernal, P1
Byrd, J1
Garberoglio, C1
Unger, KR1
Romney, DA1
Koc, M1
Moskaluk, CA1
Friel, CM1
Foley, EF1
Rich, TA1
Mc Bride, WH1
Jakobsen, A1
Mortensen, JP1
Bisgaard, C1
Lindebjerg, J1
Rafaelsen, SR1
Bendtsen, VO1

Trials

6 trials available for celecoxib and Cancer of Rectum

ArticleYear
Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study.
    Journal of surgical oncology, 2014, Volume: 109, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Chemoradioth

2014
[Perioperative immunomodulatory therapy does not decrease postoperative recurrence rate of rectal cancer].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2015, Volume: 35, Issue:4

    Topics: C-Reactive Protein; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Immunomodulation; Inflammation;

2015
Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 93, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Combined Modality Therapy; D

2009
A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer.
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitab

2010
Molecular responses of rectal cancer to preoperative chemoradiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Aged; Biomarkers, Tumor; Celecoxib; Cyclooxygenase 2; Female; Fluorouracil; Humans; Immunohis

2006
A COX-2 inhibitor combined with chemoradiation of locally advanced rectal cancer: a phase II trial.
    International journal of colorectal disease, 2008, Volume: 23, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cardiovascular

2008

Other Studies

1 other study available for celecoxib and Cancer of Rectum

ArticleYear
Preoperative chemoradiation for rectal cancer using capecitabine and celecoxib correlated with posttreatment assessment of thymidylate synthase and thymidine phosphorylase expression.
    International journal of radiation oncology, biology, physics, 2011, Aug-01, Volume: 80, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cape

2011