Page last updated: 2024-10-24

celecoxib and Brain Swelling

celecoxib has been researched along with Brain Swelling in 5 studies

Research Excerpts

ExcerptRelevanceReference
"We investigated the effect of celecoxib, a selective inhibitor of cyclo-oxygenase 2, in patients with intracerebral hemorrhage (ICH)."9.17Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial. ( Bae, HJ; Chung, JW; Han, MK; Jung, KH; Kim, CK; Kwon, HM; Lee, JS; Lee, SH; Lee, YS; Park, ES; Park, HK; Roh, JK; Ryu, WS, 2013)
"Celecoxib is a potent anti-inflammatory drug with a safety profile that has been well-demonstrated in several human diseases and is reported to have beneficial effects in a rat model of intracerebral hemorrhage (ICH)."7.75Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage. ( Chu, K; Lee, SH; Park, HK; Roh, JK, 2009)
" In this study, the authors examined whether a selective COX-2 inhibitor (celecoxib) reduces cerebral inflammation and edema after intracerebral hemorrhage (ICH), and whether functional recovery is sustained with longer treatment."7.72Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. ( Chu, K; Han, SY; Jeong, SW; Jung, KH; Kim, M; Lee, ST; Roh, JK, 2004)
"We investigated the effect of celecoxib, a selective inhibitor of cyclo-oxygenase 2, in patients with intracerebral hemorrhage (ICH)."5.17Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial. ( Bae, HJ; Chung, JW; Han, MK; Jung, KH; Kim, CK; Kwon, HM; Lee, JS; Lee, SH; Lee, YS; Park, ES; Park, HK; Roh, JK; Ryu, WS, 2013)
"These cases revealed that low-dose celecoxib may be an effective management for symptoms caused by perihematomal edema in patients with ICH, particularly those involving the thalamus."4.12Improvement After Celecoxib Treatment in Patients with Thalamic Hemorrhage - A Case Report. ( Jeng, JS; Lin, YW; Tang, SC; Tsai, LK; Yeh, SJ, 2022)
"Celecoxib is a potent anti-inflammatory drug with a safety profile that has been well-demonstrated in several human diseases and is reported to have beneficial effects in a rat model of intracerebral hemorrhage (ICH)."3.75Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage. ( Chu, K; Lee, SH; Park, HK; Roh, JK, 2009)
" In this study, the authors examined whether a selective COX-2 inhibitor (celecoxib) reduces cerebral inflammation and edema after intracerebral hemorrhage (ICH), and whether functional recovery is sustained with longer treatment."3.72Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. ( Chu, K; Han, SY; Jeong, SW; Jung, KH; Kim, M; Lee, ST; Roh, JK, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Lin, YW1
Yeh, SJ1
Tang, SC1
Tsai, LK1
Jeng, JS1
Lee, SH2
Park, HK2
Ryu, WS1
Lee, JS1
Bae, HJ1
Han, MK1
Lee, YS1
Kwon, HM1
Kim, CK1
Park, ES1
Chung, JW1
Jung, KH2
Roh, JK3
Chu, K2
Sangha, N1
Gonzales, NR1
Jeong, SW1
Han, SY1
Lee, ST1
Kim, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects and Mechanisms of Celecoxib on Intracerebral Hemorrhage[NCT05434065]Phase 260 participants (Anticipated)Interventional2023-01-01Recruiting
Multi-center, Prospective Randomized, Comparative Open With Blinded Endpoints (PROBE) Trial to Assess the Safety and Effectiveness of Administration of Celecoxib in Patients With Intracerebral Hemorrhage[NCT00526214]44 participants (Actual)Interventional2007-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for celecoxib and Brain Swelling

ArticleYear
Treatment targets in intracerebral hemorrhage.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2011, Volume: 8, Issue:3

    Topics: Anti-Inflammatory Agents; Blood Pressure; Brain Edema; Celecoxib; Cerebral Amyloid Angiopathy; Cereb

2011

Trials

1 trial available for celecoxib and Brain Swelling

ArticleYear
Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial.
    European journal of neurology, 2013, Volume: 20, Issue:8

    Topics: Aged; Aged, 80 and over; Brain Edema; Celecoxib; Cerebral Hemorrhage; Cyclooxygenase 2 Inhibitors; D

2013

Other Studies

3 other studies available for celecoxib and Brain Swelling

ArticleYear
Improvement After Celecoxib Treatment in Patients with Thalamic Hemorrhage - A Case Report.
    Acta neurologica Taiwanica, 2022, Dec-30, Volume: 31(4)

    Topics: Brain Edema; Celecoxib; Cerebral Hemorrhage; Edema; Hematoma; Humans

2022
Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage.
    Journal of the neurological sciences, 2009, Apr-15, Volume: 279, Issue:1-2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Brain Edema; Celecoxib; Cerebral Hemorrhage; Female;

2009
Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2004, Volume: 24, Issue:8

    Topics: Animals; Brain Edema; Celecoxib; Cerebral Hemorrhage; Collagenases; Cyclooxygenase Inhibitors; Dinop

2004