Page last updated: 2024-10-24

celecoxib and Brain Ischemia

celecoxib has been researched along with Brain Ischemia in 7 studies

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Celecoxib treatment decreased polyubiquitinated protein load and ER stress marker expression such as glucose-related protein 78 (GRP78), C/EBP (CCAAT/enhancer-binding protein) homologous protein (CHOP), and caspase 12 after 48 h of reperfusion."1.62Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome. ( Anuncibay-Soto, B; Fernández-López, A; Font-Belmonte, E; González-Rodríguez, P; Pérez-Rodríguez, D; Santos-Galdiano, M; Ugidos, IF, 2021)
"We concluded that cerebrovascular diseases (CD) can lead to ISH and that the COX-2 inhibitor can be an effective prophylactic drug for ISH after CD."1.31COX-2 inhibitor for the treatment of idiopathic stabbing headache secondary to cerebrovascular diseases. ( Kowacs, PA; Piovesan, EJ; Werneck, LC; Zukerman, E, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Wang, H1
Cui, E1
Li, J1
Ma, X1
Jiang, X1
Du, S1
Qian, S1
Du, L1
Santos-Galdiano, M1
González-Rodríguez, P1
Font-Belmonte, E1
Ugidos, IF1
Anuncibay-Soto, B1
Pérez-Rodríguez, D1
Fernández-López, A1
Tso, MK1
Turgeon, P1
Bosche, B1
Lee, CK1
Nie, T1
D'Abbondanza, J1
Ai, J1
Marsden, PA1
Macdonald, RL1
Seo, JH1
Park, HP1
Jeon, YT1
Lim, YJ1
Nam, K1
Hwang, JW1
Ji, B1
Kumata, K1
Onoe, H1
Kaneko, H1
Zhang, MR1
Seki, C1
Ono, M1
Shukuri, M1
Tokunaga, M1
Minamihisamatsu, T1
Suhara, T1
Higuchi, M1
Andersohn, F1
Schade, R1
Suissa, S1
Garbe, E1
Piovesan, EJ1
Zukerman, E1
Kowacs, PA1
Werneck, LC1

Other Studies

7 other studies available for celecoxib and Brain Ischemia

ArticleYear
Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment.
    European journal of medicinal chemistry, 2022, Nov-05, Volume: 241

    Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Cyclooxygenase 2; Disease Models, Animal; Indazol

2022
Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome.
    Molecular neurobiology, 2021, Volume: 58, Issue:4

    Topics: Animals; Apoptosis; Autophagy; Biomarkers; Brain Ischemia; Celecoxib; Disease Models, Animal; eIF-2

2021
Gene expression profiling of brain endothelial cells after experimental subarachnoid haemorrhage.
    Scientific reports, 2021, 04-09, Volume: 11, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain Injuries; Brain Ischemia; Celecoxib; Cyclooxygenase 2; Cyclooxyg

2021
Combined treatment with celecoxib and sevoflurane after global cerebral ischaemia has no additive neuroprotective effects in rats.
    British journal of anaesthesia, 2013, Volume: 110, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Syner

2013
Assessment of radioligands for PET imaging of cyclooxygenase-2 in an ischemic neuronal injury model.
    Brain research, 2013, Oct-02, Volume: 1533

    Topics: Animals; Antibodies; Brain; Brain Ischemia; Carbon Radioisotopes; Celecoxib; Cyclooxygenase 2; Disea

2013
Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study.
    Stroke, 2006, Volume: 37, Issue:7

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Case-Control Studi

2006
COX-2 inhibitor for the treatment of idiopathic stabbing headache secondary to cerebrovascular diseases.
    Cephalalgia : an international journal of headache, 2002, Volume: 22, Issue:3

    Topics: Aged; Brain Ischemia; Celecoxib; Cerebrovascular Disorders; Cyclooxygenase 2; Cyclooxygenase 2 Inhib

2002