celecoxib has been researched along with Brain Hemorrhage, Cerebral in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effect of celecoxib, a selective inhibitor of cyclo-oxygenase 2, in patients with intracerebral hemorrhage (ICH)." | 9.17 | Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial. ( Bae, HJ; Chung, JW; Han, MK; Jung, KH; Kim, CK; Kwon, HM; Lee, JS; Lee, SH; Lee, YS; Park, ES; Park, HK; Roh, JK; Ryu, WS, 2013) |
| "Celecoxib is a potent anti-inflammatory drug with a safety profile that has been well-demonstrated in several human diseases and is reported to have beneficial effects in a rat model of intracerebral hemorrhage (ICH)." | 7.75 | Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage. ( Chu, K; Lee, SH; Park, HK; Roh, JK, 2009) |
| "Memantine, a N-methyl-D-aspartate (NMDA) receptor antagonist, inhibits hematoma expansion and celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, reduces perihematomal inflammation in intracerebral hemorrhage." | 7.74 | Combined neuroprotective effects of celecoxib and memantine in experimental intracerebral hemorrhage. ( Chu, K; Jung, KH; Kim, JM; Kim, M; Lee, ST; Park, DK; Roh, JK; Sinn, DI; Song, EC, 2007) |
| " In this study, the authors examined whether a selective COX-2 inhibitor (celecoxib) reduces cerebral inflammation and edema after intracerebral hemorrhage (ICH), and whether functional recovery is sustained with longer treatment." | 7.72 | Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. ( Chu, K; Han, SY; Jeong, SW; Jung, KH; Kim, M; Lee, ST; Roh, JK, 2004) |
| "To report a case of intracerebral hemorrhage following short-term, concomitant use of celecoxib and clopidogrel." | 7.71 | Intracerebral hemorrhage following possible interaction between celecoxib and clopidogrel. ( Fisher, AA; Le Couteur, DG, 2001) |
| "We investigated the effect of celecoxib, a selective inhibitor of cyclo-oxygenase 2, in patients with intracerebral hemorrhage (ICH)." | 5.17 | Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial. ( Bae, HJ; Chung, JW; Han, MK; Jung, KH; Kim, CK; Kwon, HM; Lee, JS; Lee, SH; Lee, YS; Park, ES; Park, HK; Roh, JK; Ryu, WS, 2013) |
| "Overall, the use of NSAIDs is not associated with an increased risk of hemorrhagic stroke, although this risk was modestly significantly elevated in diclofenac and meloxicam users." | 4.93 | Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies. ( Matteson, EL; Thongprayoon, C; Ungprasert, P, 2016) |
| "These cases revealed that low-dose celecoxib may be an effective management for symptoms caused by perihematomal edema in patients with ICH, particularly those involving the thalamus." | 4.12 | Improvement After Celecoxib Treatment in Patients with Thalamic Hemorrhage - A Case Report. ( Jeng, JS; Lin, YW; Tang, SC; Tsai, LK; Yeh, SJ, 2022) |
| "Celecoxib is a potent anti-inflammatory drug with a safety profile that has been well-demonstrated in several human diseases and is reported to have beneficial effects in a rat model of intracerebral hemorrhage (ICH)." | 3.75 | Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage. ( Chu, K; Lee, SH; Park, HK; Roh, JK, 2009) |
| "Memantine, a N-methyl-D-aspartate (NMDA) receptor antagonist, inhibits hematoma expansion and celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, reduces perihematomal inflammation in intracerebral hemorrhage." | 3.74 | Combined neuroprotective effects of celecoxib and memantine in experimental intracerebral hemorrhage. ( Chu, K; Jung, KH; Kim, JM; Kim, M; Lee, ST; Park, DK; Roh, JK; Sinn, DI; Song, EC, 2007) |
| " In this study, the authors examined whether a selective COX-2 inhibitor (celecoxib) reduces cerebral inflammation and edema after intracerebral hemorrhage (ICH), and whether functional recovery is sustained with longer treatment." | 3.72 | Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. ( Chu, K; Han, SY; Jeong, SW; Jung, KH; Kim, M; Lee, ST; Roh, JK, 2004) |
| "To report a case of intracerebral hemorrhage following short-term, concomitant use of celecoxib and clopidogrel." | 3.71 | Intracerebral hemorrhage following possible interaction between celecoxib and clopidogrel. ( Fisher, AA; Le Couteur, DG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, YW | 1 |
| Yeh, SJ | 1 |
| Tang, SC | 1 |
| Tsai, LK | 1 |
| Jeng, JS | 1 |
| Lee, SH | 2 |
| Park, HK | 2 |
| Ryu, WS | 1 |
| Lee, JS | 1 |
| Bae, HJ | 1 |
| Han, MK | 1 |
| Lee, YS | 1 |
| Kwon, HM | 1 |
| Kim, CK | 1 |
| Park, ES | 1 |
| Chung, JW | 1 |
| Jung, KH | 3 |
| Roh, JK | 4 |
| Ungprasert, P | 1 |
| Matteson, EL | 1 |
| Thongprayoon, C | 1 |
| Chu, K | 3 |
| Sangha, N | 1 |
| Gonzales, NR | 1 |
| Jeong, SW | 1 |
| Han, SY | 1 |
| Lee, ST | 2 |
| Kim, M | 2 |
| Sinn, DI | 1 |
| Song, EC | 1 |
| Kim, JM | 1 |
| Park, DK | 1 |
| Fisher, AA | 1 |
| Le Couteur, DG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects and Mechanisms of Celecoxib on Intracerebral Hemorrhage[NCT05434065] | Phase 2 | 60 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | ||
| Multi-center, Prospective Randomized, Comparative Open With Blinded Endpoints (PROBE) Trial to Assess the Safety and Effectiveness of Administration of Celecoxib in Patients With Intracerebral Hemorrhage[NCT00526214] | 44 participants (Actual) | Interventional | 2007-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for celecoxib and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprof | 2016 |
Treatment targets in intracerebral hemorrhage.
Topics: Anti-Inflammatory Agents; Blood Pressure; Brain Edema; Celecoxib; Cerebral Amyloid Angiopathy; Cereb | 2011 |
1 trial available for celecoxib and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial.
Topics: Aged; Aged, 80 and over; Brain Edema; Celecoxib; Cerebral Hemorrhage; Cyclooxygenase 2 Inhibitors; D | 2013 |
5 other studies available for celecoxib and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Improvement After Celecoxib Treatment in Patients with Thalamic Hemorrhage - A Case Report.
Topics: Brain Edema; Celecoxib; Cerebral Hemorrhage; Edema; Hematoma; Humans | 2022 |
Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Brain Edema; Celecoxib; Cerebral Hemorrhage; Female; | 2009 |
Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death.
Topics: Animals; Brain Edema; Celecoxib; Cerebral Hemorrhage; Collagenases; Cyclooxygenase Inhibitors; Dinop | 2004 |
Combined neuroprotective effects of celecoxib and memantine in experimental intracerebral hemorrhage.
Topics: Animals; Caspase 3; CD11b Antigen; Celecoxib; Cerebral Hemorrhage; Collagenases; Disease Models, Ani | 2007 |
Intracerebral hemorrhage following possible interaction between celecoxib and clopidogrel.
Topics: Aged; Aged, 80 and over; Celecoxib; Cerebral Hemorrhage; Clopidogrel; Cyclooxygenase Inhibitors; Dru | 2001 |