celecoxib has been researched along with Bone Loss, Osteoclastic in 14 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Celecoxib (CEL), a selective cyclooxygenase-2 (COX-2) inhibitor, has been reported to suppress osteoclastogenesis in vitro, reduce levels of bone resorption markers in ovariectomized (OVX) mice, and prevent bone destruction in rheumatoid arthritis (RA) model mice; however, no clinical data has been reported." | 7.80 | Celecoxib, a selective cyclooxygenase-2 inhibitor, reduces level of a bone resorption marker in postmenopausal women with rheumatoid arthritis. ( Hamada, M; Kawai, H; Nakase, T; Tomita, T; Tsuji, S; Yoshikawa, H, 2014) |
| "Celecoxib (CEL), a selective cyclooxygenase-2 (COX-2) inhibitor, has been reported to suppress osteoclastogenesis in vitro, reduce levels of bone resorption markers in ovariectomized (OVX) mice, and prevent bone destruction in rheumatoid arthritis (RA) model mice; however, no clinical data has been reported." | 3.80 | Celecoxib, a selective cyclooxygenase-2 inhibitor, reduces level of a bone resorption marker in postmenopausal women with rheumatoid arthritis. ( Hamada, M; Kawai, H; Nakase, T; Tomita, T; Tsuji, S; Yoshikawa, H, 2014) |
| "Celecoxib treatment reduced osteoclast formation in apical periodontitis, regardless of the period of treatment (P < 0." | 1.62 | Celecoxib treatment dampens LPS-induced periapical bone resorption in a mouse model. ( Almeida-Junior, LA; Arnez, MFM; Faccioli, LH; Paula-Silva, FWG; Petean, IBF; Queiroz, AM; Silva, LAB; Silva, RAB, 2021) |
| "Infection, inflammation and bone resorption are closely related events in apical periodontitis development." | 1.51 | Periapical bone response to bacterial lipopolysaccharide is shifted upon cyclooxygenase blockage. ( Arnez, MFM; Faccioli, LH; Paula-Silva, FWG; Petean, IBF; Ribeiro-Santos, FR; Silva, GGD; Silva, LABD, 2019) |
| "The treatment with celecoxib did not modify substantially the histological alterations and the number of active osteoclasts after activation of orthodontic appliance." | 1.38 | Celecoxib treatment does not alter recruitment and activation of osteoclasts in the initial phase of experimental tooth movement. ( Carvalho-Filho, EP; Ervolino, E; Iyomasa, MM; Rocha, MJ; Stabile, AC; Stuani, MB, 2012) |
| "The treatment with celecoxib or vehicle was started immediately after the sham operation or ovariectomy, and lasted for 4 weeks." | 1.34 | The selective cyclooxygenase-2 inhibitor celecoxib reduces bone resorption, but not bone formation, in ovariectomized mice in vivo. ( Baylink, DJ; Itoi, E; Kasukawa, Y; Maekawa, S; Miyakoshi, N; Mohan, S; Nozaka, K; Srivastava, AK, 2007) |
| "The osteolysis is believed to be driven by a host inflammatory response to wear debris generated from the implant." | 1.31 | Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis. ( Boyce, BF; Langenbach, R; Morham, SG; O'Keefe, RJ; Puzas, EJ; Rosier, RN; Schwarz, EM; Xing, L; Young, DA; Zhang, X, 2001) |
| "Bone resorption was evaluated by measuring calcium released into the culture medium in a neonatal mouse calvarial bone organ culture." | 1.31 | Effects of a selective cyclooxygenase-2 inhibitor, celecoxib, on bone resorption and osteoclastogenesis in vitro. ( Igarashi, K; Stern, PH; Woo, JT, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Petean, IBF | 2 |
| Almeida-Junior, LA | 1 |
| Arnez, MFM | 2 |
| Queiroz, AM | 1 |
| Silva, RAB | 1 |
| Silva, LAB | 1 |
| Faccioli, LH | 2 |
| Paula-Silva, FWG | 2 |
| Neog, MK | 1 |
| Joshua Pragasam, S | 1 |
| Krishnan, M | 1 |
| Rasool, M | 1 |
| Ribeiro-Santos, FR | 1 |
| Silva, GGD | 1 |
| Silva, LABD | 1 |
| Tsuji, S | 1 |
| Tomita, T | 1 |
| Nakase, T | 1 |
| Hamada, M | 1 |
| Kawai, H | 1 |
| Yoshikawa, H | 1 |
| Liu, Y | 1 |
| Cui, Y | 1 |
| Chen, Y | 1 |
| Gao, X | 1 |
| Su, Y | 1 |
| Cui, L | 1 |
| Kawashima, M | 1 |
| Fujikawa, Y | 1 |
| Itonaga, I | 1 |
| Takita, C | 1 |
| Tsumura, H | 1 |
| Zhang, F | 1 |
| Tanaka, H | 1 |
| Kawato, T | 1 |
| Kitami, S | 1 |
| Nakai, K | 1 |
| Motohashi, M | 1 |
| Suzuki, N | 1 |
| Wang, CL | 1 |
| Ochiai, K | 1 |
| Isokawa, K | 1 |
| Maeno, M | 1 |
| Geng, DC | 1 |
| Zhu, XS | 1 |
| Mao, HQ | 1 |
| Meng, B | 1 |
| Chen, L | 1 |
| Yang, HL | 1 |
| Xu, YZ | 1 |
| Le, P | 1 |
| Kawai, M | 1 |
| Bornstein, S | 1 |
| DeMambro, VE | 1 |
| Horowitz, MC | 1 |
| Rosen, CJ | 1 |
| Carvalho-Filho, EP | 1 |
| Stabile, AC | 1 |
| Ervolino, E | 1 |
| Stuani, MB | 1 |
| Iyomasa, MM | 1 |
| Rocha, MJ | 1 |
| Kasukawa, Y | 1 |
| Miyakoshi, N | 1 |
| Srivastava, AK | 1 |
| Nozaka, K | 1 |
| Maekawa, S | 1 |
| Baylink, DJ | 1 |
| Mohan, S | 1 |
| Itoi, E | 1 |
| Niki, Y | 1 |
| Takaishi, H | 1 |
| Takito, J | 1 |
| Miyamoto, T | 1 |
| Kosaki, N | 1 |
| Matsumoto, H | 1 |
| Toyama, Y | 1 |
| Tada, N | 1 |
| Zhang, X | 1 |
| Morham, SG | 1 |
| Langenbach, R | 1 |
| Young, DA | 1 |
| Xing, L | 1 |
| Boyce, BF | 1 |
| Puzas, EJ | 1 |
| Rosier, RN | 1 |
| O'Keefe, RJ | 1 |
| Schwarz, EM | 1 |
| Igarashi, K | 1 |
| Woo, JT | 1 |
| Stern, PH | 1 |
14 other studies available for celecoxib and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Celecoxib treatment dampens LPS-induced periapical bone resorption in a mouse model.
Topics: Animals; Bone Resorption; Celecoxib; Escherichia coli; Lipopolysaccharides; Mice; Mice, Inbred C57BL | 2021 |
p-Coumaric acid, a dietary polyphenol ameliorates inflammation and curtails cartilage and bone erosion in the rheumatoid arthritis rat model.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Bone Resorption; Cartilage; Celecoxib; Coum | 2017 |
Periapical bone response to bacterial lipopolysaccharide is shifted upon cyclooxygenase blockage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Celecoxib; Cyclooxygenase 2; Cycl | 2019 |
Celecoxib, a selective cyclooxygenase-2 inhibitor, reduces level of a bone resorption marker in postmenopausal women with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Biomarkers; Bone Resorption; Celecoxib; Cyclooxygenase 2 Inhibitors; Dr | 2014 |
Effects of dexamethasone, celecoxib, and methotrexate on the histology and metabolism of bone tissue in healthy Sprague Dawley rats.
Topics: Animals; Antirheumatic Agents; Biomarkers; Body Weight; Bone and Bones; Bone Density; Bone Resorptio | 2015 |
The effect of selective cyclooxygenase-2 inhibitor on human osteoclast precursors to influence osteoclastogenesis in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Celecoxib; Cell Growth Processes; Cell Sur | 2009 |
Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts.
Topics: 3T3 Cells; Acid Phosphatase; Animals; Bone Resorption; Carbonic Anhydrase II; Cathepsin K; Celecoxib | 2011 |
Protection against titanium particle-induced osteoclastogenesis by cyclooxygenase-2 selective inhibitor.
Topics: Acid Phosphatase; Animals; Bone Resorption; Cathepsin K; Celecoxib; Cell Differentiation; Cell Line; | 2011 |
A high-fat diet induces bone loss in mice lacking the Alox5 gene.
Topics: Animals; Arachidonate 5-Lipoxygenase; Bone Density; Bone Resorption; Celecoxib; Cyclooxygenase 2; Cy | 2012 |
Celecoxib treatment does not alter recruitment and activation of osteoclasts in the initial phase of experimental tooth movement.
Topics: Animals; Bone Resorption; Celecoxib; Cyclooxygenase 2 Inhibitors; Follow-Up Studies; Models, Animal; | 2012 |
The selective cyclooxygenase-2 inhibitor celecoxib reduces bone resorption, but not bone formation, in ovariectomized mice in vivo.
Topics: Analysis of Variance; Animals; Bone Density; Bone Resorption; Celecoxib; Collagen Type I; Cyclooxyge | 2007 |
Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bon | 2007 |
Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis.
Topics: Animals; Bone Resorption; Celecoxib; Cells, Cultured; Crosses, Genetic; Cyclooxygenase 1; Cyclooxyge | 2001 |
Effects of a selective cyclooxygenase-2 inhibitor, celecoxib, on bone resorption and osteoclastogenesis in vitro.
Topics: Animals; Bone Resorption; Calcium; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycloox | 2002 |