Page last updated: 2024-10-24

celecoxib and Blood Loss, Surgical

celecoxib has been researched along with Blood Loss, Surgical in 9 studies

Blood Loss, Surgical: Loss of blood during a surgical procedure.

Research Excerpts

ExcerptRelevanceReference
"Celecoxib does not increase perioperative blood loss but reduces pain during the postoperative period after TKR."2.73Effects of celecoxib on blood loss, pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial. ( Good, L; Lisander, B; Meunier, A, 2007)
"Morphine use was lower in the celecoxib group at all postoperative time-intervals."2.71The effect of cyclooxygenase-2 inhibition on analgesia and spinal fusion. ( Ekman, EF; Reuben, SS, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhao, HY1
Kang, PD1
Xia, YY1
Shi, XJ1
Nie, Y1
Pei, FX1
Scott, WW1
Levy, M1
Rickert, KL1
Madden, CJ1
Beshay, JE1
Sarode, R1
Teerawattananon, C1
Tantayakom, P1
Suwanawiboon, B1
Katchamart, W1
Huang, YM1
Wang, CM1
Wang, CT1
Lin, WP1
Horng, LC1
Jiang, CC1
Reuben, SS3
Ekman, EF1
Meunier, A1
Lisander, B1
Good, L1
Buvenandran, A1
Katz, B1
Kroin, JS1
Rosenstein, ED1
Kushner, LJ1
Kramer, N1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study on Pain and Sensation After Regional Anesthesia for Total Hip Arthroplasty[NCT03623035]10 participants (Actual)Observational2018-08-16Completed
Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients[NCT02160301]Phase 40 participants (Actual)Interventional2017-11-30Withdrawn (stopped due to Insufficient infrastructure/funding for enrollment)
Perioperative Pain Control With Celecoxib (Celebrex) in Total Knee Arthroplasty[NCT00598234]Phase 4120 participants (Anticipated)Interventional2006-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Reporting Pin Prick Sensation

Assessment for spinal resolution below the level of L5/S1 by assessing the presence of pin prick sensation at these levels. (NCT03623035)
Timeframe: 6 Hours post block placement

InterventionParticipants (Count of Participants)
Lumbar Plexus Block Group9

Patient Pain Score With Activity

Pain scores will be measured on a verbal pain score when participant sits up in bed. Totals Score range 0-10. Lower scores denote better outcomes. (NCT03623035)
Timeframe: 6 Hours post block placement

Interventionunits on a scale (Mean)
Lumbar Plexus Block Group1.4

Patient Pain Scores at Rest

Pain scores will be measured, when the patient is laying still in bed, on a verbal pain scale. Totals Score range 0-10. Lower scores denote better outcomes. (NCT03623035)
Timeframe: 6 Hours post block placement

Interventionunits on a scale (Mean)
Lumbar Plexus Block Group1

Reviews

1 review available for celecoxib and Blood Loss, Surgical

ArticleYear
Risk of perioperative bleeding related to highly selective cyclooxygenase-2 inhibitors: A systematic review and meta-analysis.
    Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4

    Topics: Blood Loss, Surgical; Celecoxib; Cyclooxygenase 2 Inhibitors; Etoricoxib; Humans; Isoxazoles; Postop

2017

Trials

6 trials available for celecoxib and Blood Loss, Surgical

ArticleYear
Comparison of Early Functional Recovery After Total Hip Arthroplasty Using a Direct Anterior or Posterolateral Approach: A Randomized Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:11

    Topics: Adult; Aged; Anesthesia; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Celecoxib; China; Fem

2017
Assessment of common nonsteroidal anti-inflammatory medications by whole blood aggregometry: a clinical evaluation for the perioperative setting.
    World neurosurgery, 2014, Volume: 82, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Celecoxib; Cyclooxygenase Inhi

2014
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
    BMC musculoskeletal disorders, 2008, Jun-03, Volume: 9

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar

2008
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
    BMC musculoskeletal disorders, 2008, Jun-03, Volume: 9

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar

2008
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
    BMC musculoskeletal disorders, 2008, Jun-03, Volume: 9

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar

2008
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
    BMC musculoskeletal disorders, 2008, Jun-03, Volume: 9

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar

2008
The effect of cyclooxygenase-2 inhibition on analgesia and spinal fusion.
    The Journal of bone and joint surgery. American volume, 2005, Volume: 87, Issue:3

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Celecoxib; Cycloox

2005
Effects of celecoxib on blood loss, pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial.
    Acta orthopaedica, 2007, Volume: 78, Issue:5

    Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee;

2007
A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomes.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:4

    Topics: Aged; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacem

2008

Other Studies

2 other studies available for celecoxib and Blood Loss, Surgical

ArticleYear
The safety of the perioperative administration of cyclooxygenase-2 inhibitors for post-surgical pain.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty; Blood Loss, Surgical; Celecoxib; Child; Cyclo

2005
Rheumatoid arthritis.
    Journal of the American Dental Association (1939), 1999, Volume: 130, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Aurothioglucos

1999