Page last updated: 2024-10-24

celecoxib and Barrett Epithelium

celecoxib has been researched along with Barrett Epithelium in 11 studies

Research Excerpts

ExcerptRelevanceReference
"To study the feasibility of chemoprevention of esophageal adenocarcinoma by celecoxib, a selective cyclooxygenase-2(COX-2) inhibitor using a rat model."7.78[An experimental study on chemoprevention of esophageal adenocarcinoma by celecoxib, a selective cyclooxygenase-2 inhibitor]. ( Lang, HJ; Liang, XH; Su, LW; Wang, YJ; Zhang, F; Zhang, T; Zhou, YA; Zhu, YF, 2012)
"To study the feasibility of chemoprevention of esophageal adenocarcinoma by celecoxib, a selective cyclooxygenase-2(COX-2) inhibitor using a rat model."3.78[An experimental study on chemoprevention of esophageal adenocarcinoma by celecoxib, a selective cyclooxygenase-2 inhibitor]. ( Lang, HJ; Liang, XH; Su, LW; Wang, YJ; Zhang, F; Zhang, T; Zhou, YA; Zhu, YF, 2012)
"Although evidence suggests that aspirin and celecoxib may reduce the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus (BE), these drugs can also cause harmful side effects."3.74Patient preferences for the chemoprevention of esophageal adenocarcinoma in Barrett's esophagus. ( Broughton, DE; Gazelle, GS; Hur, C; Nishioka, NS; Ozanne, E; Yachimski, P, 2008)
"A series of 90 rats underwent a duodenoesophageal reflux surgery were divided into 2 groups: the control group was given a commercial chow and the celecoxib group experimental chow containing celecoxib."3.73[A COX-2 inhibitor suppresses esophageal inflammation-metaplasia-adenocarcinoma sequence in rats]. ( Fujimura, T; Miwa, K; Oyama, K, 2005)
"The Chemoprevention for Barrett's Esophagus Trial (CBET) was a phase IIb, multicenter, randomized, placebo-controlled trial of celecoxib in patients with Barrett's esophagus."2.73Quantitative endoscopy in the chemoprevention of Barrett's Esophagus Trial. ( Forastiere, AA; Gaudard, MA; Heath, EI; Shar, AO; Sontag, SJ; Yang, VW, 2008)
" Because aspirin and other nonsteroidal anti-inflammatory drugs, such as celecoxib, may decrease the risk of developing esophageal cancer, we investigated the effect of long-term administration of celecoxib in patients with Barrett's esophagus with dysplasia."2.73Secondary chemoprevention of Barrett's esophagus with celecoxib: results of a randomized trial. ( Canto, MI; Dannenberg, AJ; Forastiere, AA; Hawk, E; Heath, EI; Herman, JG; Montgomery, E; Piantadosi, S; Shar, AO; Weinstein, WM; Yang, VW, 2007)
"Celecoxib treatment decreased the incidence of EA in rats undergoing EJA with H."1.37Effect of Helicobacter pylori infection on Barrett's esophagus and esophageal adenocarcinoma formation in a rat model of chronic gastroesophageal reflux. ( Gao, PP; Li, J; Liu, FX; Wang, J; Wang, WH, 2011)
"examined Barrett's esophagus patient preferences for cancer chemoprevention with either aspirin or celecoxib."1.35Chemoprevention and Barrett's esophagus: decisions, decisions. ( Falk, GW; Jankowski, J, 2008)
"The Chemoprevention for Barrett's Esophagus Trial (CBET) was a phase IIb, multicenter, randomized, placebo-controlled trial of celecoxib in patients with Barrett's esophagus."1.35Modeling using baseline characteristics in a small multicenter clinical trial for Barrett's esophagus. ( Forastiere, AA; Gaudard, MA; Heath, EI; Shar, AO; Sontag, SJ; Yang, VW, 2009)
"The degree of inflammation, Barrett's esophagus, adenocarcinoma, COX-2 expression and PGE(2) of animals were assessed."1.35[Chemoprevention of Barrett's esophagus by celecoxib in rats]. ( Chen, X; Li, GD; Ou-Yang, Q; Wang, RH; Xiang, JY, 2009)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (72.73)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shar, AO3
Gaudard, MA2
Heath, EI3
Forastiere, AA3
Yang, VW3
Sontag, SJ2
Falk, GW1
Jankowski, J1
Hur, C1
Broughton, DE1
Ozanne, E1
Yachimski, P1
Nishioka, NS1
Gazelle, GS1
Wang, RH1
Ou-Yang, Q1
Chen, X1
Li, GD1
Xiang, JY1
Triadafilopoulos, G1
Lombard, CM1
Jobe, BA1
Liu, FX1
Wang, WH1
Wang, J1
Li, J1
Gao, PP1
Zhang, T1
Su, LW1
Zhu, YF1
Lang, HJ1
Zhang, F1
Zhou, YA1
Liang, XH1
Wang, YJ1
Miwa, K1
Oyama, K1
Fujimura, T1
Canto, MI1
Piantadosi, S1
Montgomery, E1
Weinstein, WM1
Herman, JG1
Dannenberg, AJ1
Hawk, E1
Jacobson, GA1
Narkowicz, C1
Lord, R1
Howard, BJ1
Chung, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Chemoprevention for Barrett's Esophagus Trial (CBET)[NCT00005878]Phase 20 participants Interventional2000-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for celecoxib and Barrett Epithelium

ArticleYear
Quantitative endoscopy in the chemoprevention of Barrett's Esophagus Trial.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2008, Volume: 21, Issue:7

    Topics: Barrett Esophagus; Celecoxib; Cohort Studies; Cyclooxygenase Inhibitors; Endoscopy; Humans; Pyrazole

2008
Secondary chemoprevention of Barrett's esophagus with celecoxib: results of a randomized trial.
    Journal of the National Cancer Institute, 2007, Apr-04, Volume: 99, Issue:7

    Topics: Aged; Aged, 80 and over; Barrett Esophagus; Cadherins; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2

2007

Other Studies

9 other studies available for celecoxib and Barrett Epithelium

ArticleYear
Chemoprevention and Barrett's esophagus: decisions, decisions.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:10

    Topics: Adenocarcinoma; Aspirin; Barrett Esophagus; Cardiovascular Diseases; Celecoxib; Chemoprevention; Cyc

2008
Patient preferences for the chemoprevention of esophageal adenocarcinoma in Barrett's esophagus.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:10

    Topics: Adenocarcinoma; Aspirin; Barrett Esophagus; Cardiovascular Diseases; Celecoxib; Chemoprevention; Cyc

2008
Modeling using baseline characteristics in a small multicenter clinical trial for Barrett's esophagus.
    Contemporary clinical trials, 2009, Volume: 30, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Barrett Esophagus; Celecoxib; Data Interpretation, Statisti

2009
[Chemoprevention of Barrett's esophagus by celecoxib in rats].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2009, Volume: 38, Issue:5

    Topics: Animals; Barrett Esophagus; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone;

2009
"War and Peace" with Barrett's esophagus.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:4

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Barrett Esophagus; Celeco

2011
Effect of Helicobacter pylori infection on Barrett's esophagus and esophageal adenocarcinoma formation in a rat model of chronic gastroesophageal reflux.
    Helicobacter, 2011, Volume: 16, Issue:1

    Topics: Adenocarcinoma; Anastomosis, Surgical; Animals; Barrett Esophagus; CDX2 Transcription Factor; Celeco

2011
[An experimental study on chemoprevention of esophageal adenocarcinoma by celecoxib, a selective cyclooxygenase-2 inhibitor].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2012, Volume: 15, Issue:5

    Topics: Adenocarcinoma; Animals; Barrett Esophagus; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models,

2012
[A COX-2 inhibitor suppresses esophageal inflammation-metaplasia-adenocarcinoma sequence in rats].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:8

    Topics: Adenocarcinoma; Animals; Apoptosis; Barrett Esophagus; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2

2005
Effect of celecoxib on cyclooxygenase-2 expression and possible variants in a patient with Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2007, Volume: 20, Issue:3

    Topics: Adult; Barrett Esophagus; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Humans; Py

2007