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celecoxib and Asthma

celecoxib has been researched along with Asthma in 16 studies

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Eighteen subjects with asthma participated in a cross-over study where celecoxib 200mg or placebo were given b."9.15Effects of celecoxib on major prostaglandins in asthma. ( Daham, K; Dahlén, B; Dahlén, SE; FitzGerald, GA; Gülich, A; Kupczyk, M; Lawson, JA; Song, WL, 2011)
"A special regulatory role for prostaglandin E2 has been postulated in aspirin-induced asthma."9.13Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity. ( Cmiel, A; Gawlewicz-Mroczka, A; Gielicz, A; Mastalerz, L; Sanak, M; Szczeklik, A, 2008)
"To determine whether celecoxib, a selective cyclooxygenase 2 (COX-2) inhibitor, cross-reacts in patients with aspirin-exacerbated respiratory disease (AERD) with asthma."9.10The safety of celecoxib in patients with aspirin-sensitive asthma. ( Simon, RA; Stevenson, DD; Woessner, KM, 2002)
"Subjects with aspirin-intolerant asthma (AIA) respond with bronchoconstriction and extrapulmonary adverse reactions to conventional nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit the cyclooxygenase (COX) step in the biosynthesis of prostaglandins."9.10Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib. ( Bochenek, G; Dahlén, B; Dahlén, SE; Drupka, D; Gyllfors, P; Isakson, PC; Kumlin, M; Lefkowith, JB; Mejza, F; Murray, JJ; Nizankowska, E; Overholt, J; Sheller, J; Szczeklik, A, 2003)
"To review the safety of cyclooxygenase-2 (COX-2) inhibitors in asthma patients with aspirin hypersensitivity."8.82Safety of COX-2 inhibitors in asthma patients with aspirin hypersensitivity. ( Fernández, C; West, PM, 2003)
"The Fernand Widal syndrome is a set of associations between asthma, nasal polyposis and aspirin sensitivity."7.88[Is celecoxib a safe alternative for the Fernand Widal syndrome?] ( De Blay, F; Guenard-Bilbaut, L; Metz-Favre, C; Schaller, A, 2018)
"In 5-10% of adult patients with asthma, aspirin and most other nonsteroidal anti-inflammatory drugs (NSAIDs) precipitate acute asthmatic attacks."7.72Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients. ( Alfaya, T; Berges, P; Camacho, E; García-Rodriguez, R; Hinojosa, M; Martín-García, C, 2003)
"We describe the case of an aspirin-sensitive asthma patient with a history of anaphylactic reactions to nonsteroidal anti-inflammatory drugs."7.71Successful use of cyclooxygenase-2 inhibitor in a patient with aspirin-induced asthma. ( Fischer, R; Harrell, K; Marks, F, 2001)
"Eighteen subjects with asthma participated in a cross-over study where celecoxib 200mg or placebo were given b."5.15Effects of celecoxib on major prostaglandins in asthma. ( Daham, K; Dahlén, B; Dahlén, SE; FitzGerald, GA; Gülich, A; Kupczyk, M; Lawson, JA; Song, WL, 2011)
"A special regulatory role for prostaglandin E2 has been postulated in aspirin-induced asthma."5.13Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity. ( Cmiel, A; Gawlewicz-Mroczka, A; Gielicz, A; Mastalerz, L; Sanak, M; Szczeklik, A, 2008)
" Three subjects with multiple-drug induced urticaria complained of a generalized reaction after challenge (Two due to celecoxib and one due to meloxicam)."5.11Tolerability of three selective cyclo-oxygenase-2 inhibitors, meloxicam, celecoxib and rofecoxib in NSAID-sensitive patients. ( Antonicelli, L; Bilò, MB; Bonadonna, P; Crivellaro, MA; Dama, AR; Schiappoli, M; Senna, G, 2004)
"To determine whether celecoxib, a selective cyclooxygenase 2 (COX-2) inhibitor, cross-reacts in patients with aspirin-exacerbated respiratory disease (AERD) with asthma."5.10The safety of celecoxib in patients with aspirin-sensitive asthma. ( Simon, RA; Stevenson, DD; Woessner, KM, 2002)
"Subjects with aspirin-intolerant asthma (AIA) respond with bronchoconstriction and extrapulmonary adverse reactions to conventional nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit the cyclooxygenase (COX) step in the biosynthesis of prostaglandins."5.10Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib. ( Bochenek, G; Dahlén, B; Dahlén, SE; Drupka, D; Gyllfors, P; Isakson, PC; Kumlin, M; Lefkowith, JB; Mejza, F; Murray, JJ; Nizankowska, E; Overholt, J; Sheller, J; Szczeklik, A, 2003)
"Nonsteroidal anti-inflammatory drugs (NSAIDs) cause bronchospasm in susceptible patients with asthma, often termed aspirin-exacerbated respiratory disease (AERD), with the risk being greatest after acute exposure."4.90Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials. ( Donnan, PT; Guthrie, B; Jackson, C; Lipworth, BJ; Morales, DR; Santiago, VH, 2014)
"To review the safety of cyclooxygenase-2 (COX-2) inhibitors in asthma patients with aspirin hypersensitivity."4.82Safety of COX-2 inhibitors in asthma patients with aspirin hypersensitivity. ( Fernández, C; West, PM, 2003)
"The Fernand Widal syndrome is a set of associations between asthma, nasal polyposis and aspirin sensitivity."3.88[Is celecoxib a safe alternative for the Fernand Widal syndrome?] ( De Blay, F; Guenard-Bilbaut, L; Metz-Favre, C; Schaller, A, 2018)
"In 5-10% of adult patients with asthma, aspirin and most other nonsteroidal anti-inflammatory drugs (NSAIDs) precipitate acute asthmatic attacks."3.72Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients. ( Alfaya, T; Berges, P; Camacho, E; García-Rodriguez, R; Hinojosa, M; Martín-García, C, 2003)
"We describe the case of an aspirin-sensitive asthma patient with a history of anaphylactic reactions to nonsteroidal anti-inflammatory drugs."3.71Successful use of cyclooxygenase-2 inhibitor in a patient with aspirin-induced asthma. ( Fischer, R; Harrell, K; Marks, F, 2001)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (75.00)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schaller, A1
Metz-Favre, C1
Guenard-Bilbaut, L1
De Blay, F1
Morales, DR1
Lipworth, BJ1
Guthrie, B1
Jackson, C1
Donnan, PT1
Santiago, VH1
Muñoz-Cano, R1
Bartra, J1
Vennera, MC1
Valero, A1
Picado, C1
Daham, K1
Song, WL1
Lawson, JA1
Kupczyk, M1
Gülich, A1
Dahlén, SE2
FitzGerald, GA1
Dahlén, B3
Sanak, M3
Woessner, KM1
Simon, RA1
Stevenson, DD1
Gyllfors, P1
Bochenek, G1
Overholt, J1
Drupka, D1
Kumlin, M1
Sheller, J1
Nizankowska, E1
Isakson, PC1
Mejza, F1
Lefkowith, JB1
Szczeklik, A4
Murray, JJ2
Martín-García, C1
Hinojosa, M1
Berges, P1
Camacho, E1
García-Rodriguez, R1
Alfaya, T1
West, PM1
Fernández, C1
Senna, G1
Bilò, MB1
Antonicelli, L1
Schiappoli, M1
Crivellaro, MA1
Bonadonna, P1
Dama, AR1
Baldassarre, S1
Schandene, L1
Choufani, G1
Michils, A1
Mastalerz, L2
Gawlewicz, A1
Gielicz, A2
Faber, J1
Gawlewicz-Mroczka, A1
Cmiel, A1
Marks, F1
Harrell, K1
Fischer, R1
Dicpinigaitis, PV1

Reviews

2 reviews available for celecoxib and Asthma

ArticleYear
Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials.
    The Journal of allergy and clinical immunology, 2014, Volume: 134, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Celecoxib; Clinical Trial

2014
Safety of COX-2 inhibitors in asthma patients with aspirin hypersensitivity.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cyclooxygenase 2; Drug Hypersen

2003

Trials

6 trials available for celecoxib and Asthma

ArticleYear
Effects of celecoxib on major prostaglandins in asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Asthma; Celecoxib; Cross-Over Studies; Drug Administration Schedule; Female

2011
The safety of celecoxib in patients with aspirin-sensitive asthma.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cyclooxygenase Inhibitors; Dose

2002
Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cross-Over Studies

2003
Tolerability of three selective cyclo-oxygenase-2 inhibitors, meloxicam, celecoxib and rofecoxib in NSAID-sensitive patients.
    European annals of allergy and clinical immunology, 2004, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celec

2004
Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity.
    Thorax, 2008, Volume: 63, Issue:1

    Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control

2008
Effect of the cyclooxygenase-2 inhibitor celecoxib on bronchial responsiveness and cough reflex sensitivity in asthmatics.
    Pulmonary pharmacology & therapeutics, 2001, Volume: 14, Issue:2

    Topics: Adult; Airway Resistance; Asthma; Bronchi; Celecoxib; Cough; Cross-Over Studies; Cyclooxygenase 2; C

2001

Other Studies

8 other studies available for celecoxib and Asthma

ArticleYear
[Is celecoxib a safe alternative for the Fernand Widal syndrome?]
    Revue des maladies respiratoires, 2018, Volume: 35, Issue:2

    Topics: Adult; Aged; Aspirin; Asthma; Case-Control Studies; Celecoxib; Drug Hypersensitivity; Female; France

2018
Asthmatic reaction induced by celecoxib in a patient with aspirin-induced asthma.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:1

    Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Celecoxib; Cyclooxygenase Inhibitors; Drug Hypersensitivity

2009
Coxibs strike back.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:1

    Topics: Asthma; Celecoxib; Female; Humans; Male; Prostaglandins; Pyrazoles; Sulfonamides

2011
Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients.
    Journal of investigational allergology & clinical immunology, 2003, Volume: 13, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cyclooxygenase 2;

2003
Asthma attacks induced by low doses of celecoxib, aspirin, and acetaminophen.
    The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:1

    Topics: Acetaminophen; Aspirin; Asthma; Celecoxib; Cyclooxygenase Inhibitors; Female; Humans; Leukotriene E4

2006
Different eicosanoid profile of the hypersensitivity reactions triggered by aspirin and celecoxib in a patient with sinusitis, asthma, and urticaria.
    The Journal of allergy and clinical immunology, 2006, Volume: 118, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Drug Hypersensitivity; E

2006
Celecoxib in patients with asthma and aspirin intolerance. The Celecoxib in Aspirin-Intolerant Asthma Study Group.
    The New England journal of medicine, 2001, Jan-11, Volume: 344, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Spasm; Celecoxib; Cyclooxygenase 2; Cyclo

2001
Successful use of cyclooxygenase-2 inhibitor in a patient with aspirin-induced asthma.
    Southern medical journal, 2001, Volume: 94, Issue:2

    Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Asthma;

2001