Page last updated: 2024-10-24

celecoxib and Anorexia

celecoxib has been researched along with Anorexia in 5 studies

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
"Previous studies reported promising efficacy for celecoxib in the treatment of cancer cachexia."9.27Randomized double-blind clinical trial of combined treatment with megestrol acetate plus celecoxib versus megestrol acetate alone in cachexia-anorexia syndrome induced by GI cancers. ( Ala, S; Alipour, A; Borhani, S; Janbabai, G; Kouchaki, B; Salehifar, E, 2018)
" antioxidants) with carnitine + celecoxib ± megestrol acetate for the treatment of cancer-related anorexia/cachexia syndrome (CACS): the primary endpoints were increase of lean body mass (LBM) and improvement of total daily physical activity."9.16Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib ± megestrol acetate for patients with cancer-related anorexia/cachexia syndrome. ( Antoni, G; Astara, G; Cau, MC; Dessì, M; Macciò, A; Madeddu, C; Mantovani, G; Mela, Q; Montaldo, L; Mura, M; Panzone, F; Serpe, R; Tanca, FM, 2012)
"Previous studies reported promising efficacy for celecoxib in the treatment of cancer cachexia."5.27Randomized double-blind clinical trial of combined treatment with megestrol acetate plus celecoxib versus megestrol acetate alone in cachexia-anorexia syndrome induced by GI cancers. ( Ala, S; Alipour, A; Borhani, S; Janbabai, G; Kouchaki, B; Salehifar, E, 2018)
" antioxidants) with carnitine + celecoxib ± megestrol acetate for the treatment of cancer-related anorexia/cachexia syndrome (CACS): the primary endpoints were increase of lean body mass (LBM) and improvement of total daily physical activity."5.16Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib ± megestrol acetate for patients with cancer-related anorexia/cachexia syndrome. ( Antoni, G; Astara, G; Cau, MC; Dessì, M; Macciò, A; Madeddu, C; Mantovani, G; Mela, Q; Montaldo, L; Mura, M; Panzone, F; Serpe, R; Tanca, FM, 2012)
"Celecoxib 400 mg was taken orally twice daily during chemoradiation, up to 1 week before surgery, and for 6 months following surgery."2.82Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced esophageal cancer. ( Bueno, R; Choi, N; Cleary, JM; Donahue, DM; Enzinger, PC; Fidias, PM; Fuchs, CS; Gaissert, HA; Jaklitsch, MT; Kulke, MH; Lynch, TP; Mamon, HJ; Mentzer, SJ; Meyerhardt, JA; Swanson, RS; Szymonifka, J; Wain, J, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kouchaki, B1
Janbabai, G1
Alipour, A1
Ala, S1
Borhani, S1
Salehifar, E1
Cleary, JM1
Mamon, HJ1
Szymonifka, J1
Bueno, R1
Choi, N1
Donahue, DM1
Fidias, PM1
Gaissert, HA1
Jaklitsch, MT1
Kulke, MH1
Lynch, TP1
Mentzer, SJ1
Meyerhardt, JA1
Swanson, RS1
Wain, J1
Fuchs, CS1
Enzinger, PC1
Madeddu, C2
Dessì, M1
Panzone, F1
Serpe, R2
Antoni, G1
Cau, MC1
Montaldo, L1
Mela, Q1
Mura, M1
Astara, G2
Tanca, FM1
Macciò, A2
Mantovani, G2
Yamamoto, K1
Asano, K1
Ito, Y1
Matsukawa, N1
Kim, S1
Yamatodani, A1
Gramignano, G1
Lusso, MR1
Massa, E1
Deiana, L1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Cisplatin, CPT-11, Celecoxib (PCC), Concurrent Radiation Therapy, and Surgery for Resectable Esophageal Cancer[NCT00137852]Phase 235 participants (Actual)Interventional2002-01-31Completed
Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy[NCT02644408]Phase 3184 participants (Actual)Interventional2014-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for celecoxib and Anorexia

ArticleYear
Randomized double-blind clinical trial of combined treatment with megestrol acetate plus celecoxib versus megestrol acetate alone in cachexia-anorexia syndrome induced by GI cancers.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018, Volume: 26, Issue:7

    Topics: Anorexia; Antineoplastic Agents, Hormonal; Cachexia; Celecoxib; Combined Modality Therapy; Double-Bl

2018
Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced esophageal cancer.
    BMC cancer, 2016, 07-13, Volume: 16

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptot

2016
Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib ± megestrol acetate for patients with cancer-related anorexia/cachexia syndrome.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:2

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Anorexia; Appetite; Cachexia; Carnitine; Celecoxib;

2012
A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:5

    Topics: Adult; Aged; Anorexia; Ascorbic Acid; Cachexia; Carbocysteine; Celecoxib; Dietary Supplements; Docos

2006

Other Studies

1 other study available for celecoxib and Anorexia

ArticleYear
Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats.
    Toxicology, 2012, Dec-16, Volume: 302, Issue:2-3

    Topics: Animals; Anorexia; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Docetaxel; Hypothalamus

2012