Page last updated: 2024-10-24

celecoxib and Anemia

celecoxib has been researched along with Anemia in 10 studies

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
"Chronic inflammation is one of the main symptoms of cancer cachexia, and cyclooxygenase 2 inhibitors, such as celecoxib, may be beneficial in counteracting the major symptoms of this syndrome."3.81Celecoxib attenuates cachectic events in mice by modulating the expression of vascular endothelial growth factor. ( Bi, Y; Han, M; Jiang, M; Xu, X; Zhang, Y, 2015)
"The aim of this study was to predict the cost effectiveness of celecoxib, a cyclo-oxygenase 2 (COX-2) specific inhibitor, in the treatment of arthritis patients in Switzerland."3.71Economic evaluation of celecoxib, a new cyclo-oxygenase 2 specific inhibitor, in Switzerland. ( Chancellor, JV; de Cruz, E; Hunsche, E; Sarasin, FP, 2001)
"Celecoxib was prescribed at 400 mg twice daily beginning on day 1 for 1 year."2.73A Phase II study of acute toxicity for Celebrex (celecoxib) and chemoradiation in patients with locally advanced cervical cancer: primary endpoint analysis of RTOG 0128. ( Avizonis, V; Dicker, AP; Eifel, PJ; Fromm, M; Gaffney, DK; Greven, K; Miller, B; Ryu, J; Winter, K, 2007)
"Treatment of celecoxib with a proton pump inhibitor is safer than treatment with nonselective NSAID and a proton pump inhibitor in high risk gastrointestinal and cardiovascular patients who mostly also take acetylsalicylic acid."2.52[Gastrointestinal bleeding]. ( Lanas, Á, 2015)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, J1
Shen, P1
Zhang, XC1
Zhao, MD1
Zhang, XG1
Yang, L1
Xu, X1
Jiang, M1
Zhang, Y1
Bi, Y1
Han, M1
Macciò, A1
Gramignano, G1
Madeddu, C1
Lanas, Á2
Goldstein, JL2
Chan, FK1
Wilcox, CM1
Peura, D1
Sands, GH1
Berger, MF1
Nguyen, H1
Scheiman, JM1
Montano-Pedroso, JC1
Garcia, EB1
Omonte, IR1
Rocha, MG1
Ferreira, LM1
Krzyzanowska, MK1
Tannock, IF1
Lockwood, G1
Knox, J1
Moore, M1
Bjarnason, GA1
Gaffney, DK1
Winter, K1
Dicker, AP1
Miller, B1
Eifel, PJ1
Ryu, J1
Avizonis, V1
Fromm, M1
Greven, K1
Burke, TA1
Zabinski, RA1
Pettitt, D1
Maniadakis, N1
Maurath, CJ1
Chancellor, JV1
Hunsche, E1
de Cruz, E1
Sarasin, FP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Scarpa´s Fascia in the Formation of Seroma Post Abdominoplasty After Bariatric Surgery[NCT01942707]46 participants (Actual)Interventional2013-03-31Active, not recruiting
A Phase I/II Study Of COX-2 Inhibitor, CELEBREX (CELECOXIB), And Chemoradiation In Patients With Locally Advanced Cervical Cancer[NCT00023660]Phase 1/Phase 284 participants (Actual)Interventional2001-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Days Required for Drain Withdrawal.

Number of days required for drain withdrawal. The measure of drainage will be done at the same time (8:00 am) and by the same nurse everyday in all patients until the drain is withdrawn. The drain will be withdrawn when the drained volume is less than 30 ml in 24 hours. (NCT01942707)
Timeframe: Number of days required for drain withdrawal (drained volume less than 30 ml in 24 hours) and no later than 10 days

Interventiondays (Mean)
Without Scarpa's Fascia5.4
With Scarpa's Fascia4.2

Total Volume of Drainage in ml.

We will measure the total volume of drainage, in ml, obtained by the drains in the abdominal region. The measure of drainage will be done at the same time (8:00 am) and by the same nurse everyday in all patients until the drain is withdrawn. The drain will be withdrawn when the drained volume is less than 30 ml in 24 hours. Total volume of drainage will be calculated as the sum of the volumes obtained daily. (NCT01942707)
Timeframe: number of days required for drain withdrawal (drained volume less than 30 ml in 24 hours) and no later than 10 days

Interventionml (Mean)
Without Scarpa's Fascia428.9
With Scarpa's Fascia249.1

Volume of Seroma Assessed by Ultrasound of the Abdominal Wall.

An ultrasound of the abdominal wall will be realized to check the volume of any residual seroma. (NCT01942707)
Timeframe: Done after 20 days of surgery

Interventionml (Mean)
Without Scarpa's Fascia21.6
With Scarpa's Fascia16.8

Reviews

3 reviews available for celecoxib and Anemia

ArticleYear
Efficacy and safety profile of celecoxib for treating advanced cancers: a meta-analysis of 11 randomized clinical trials.
    Clinical therapeutics, 2014, Aug-01, Volume: 36, Issue:8

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cardiovascul

2014
[Gastrointestinal bleeding].
    Gastroenterologia y hepatologia, 2015, Volume: 38 Suppl 1

    Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; Celecox

2015
A framework for evaluating the clinical consequences of initial therapy with NSAIDs, NSAIDs plus gastroprotective agents, or celecoxib in the treatment of arthritis.
    PharmacoEconomics, 2001, Volume: 19 Suppl 1

    Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Clinical T

2001

Trials

4 trials available for celecoxib and Anemia

ArticleYear
Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials.
    Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:7

    Topics: Adult; Aged; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Celeco

2011
Hematological variables and iron status in abdominoplasty after bariatric surgery.
    Obesity surgery, 2013, Volume: 23, Issue:1

    Topics: Abdominoplasty; Adult; Analgesics; Anemia; Anti-Bacterial Agents; Biomarkers; Celecoxib; Cyclooxygen

2013
A phase II trial of continuous low-dose oral cyclophosphamide and celecoxib in patients with renal cell carcinoma.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:1

    Topics: Administration, Oral; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal

2007
A Phase II study of acute toxicity for Celebrex (celecoxib) and chemoradiation in patients with locally advanced cervical cancer: primary endpoint analysis of RTOG 0128.
    International journal of radiation oncology, biology, physics, 2007, Jan-01, Volume: 67, Issue:1

    Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Adeno

2007

Other Studies

3 other studies available for celecoxib and Anemia

ArticleYear
Celecoxib attenuates cachectic events in mice by modulating the expression of vascular endothelial growth factor.
    Molecular medicine reports, 2015, Volume: 11, Issue:1

    Topics: Anemia; Animals; Antibodies, Monoclonal; Body Weight; Cachexia; Celecoxib; Cell Line, Tumor; Cycloox

2015
Surprising results of a supportive integrated therapy in myelofibrosis.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:1

    Topics: Anemia; C-Reactive Protein; Cachexia; Carnitine; Celecoxib; Curcumin; Erythropoietin; Fatigue; Ferri

2015
Economic evaluation of celecoxib, a new cyclo-oxygenase 2 specific inhibitor, in Switzerland.
    PharmacoEconomics, 2001, Volume: 19 Suppl 1

    Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Clinical T

2001