celecoxib has been researched along with Aging in 9 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Finally, GTN and Celecoxib controlled inflammation in the prostate, and sensitized the senescent microenvironment to anti-inflammatory stimuli." | 7.85 | Goniothalamin and Celecoxib Effects During Aging: Targeting Pro-Inflammatory Mediators in Chemoprevention of Prostatic Disorders. ( Cagnon, VHA; Kido, LA; Montico, F; Pilli, RA; Vendramini-Costa, DB, 2017) |
| "This study evaluates the impact of celecoxib on functional status, health-related quality of life (HRQOL), and safety of elderly patients (> or =70 years) with osteoarthritis (OA) of the knee and/or hip." | 5.09 | Functional status and health-related quality of life of elderly osteoarthritic patients treated with celecoxib. ( Dedhiya, SD; Espinoza, L; Lisse, J; Osterhaus, JT; Zhao, SZ, 2001) |
| "Finally, GTN and Celecoxib controlled inflammation in the prostate, and sensitized the senescent microenvironment to anti-inflammatory stimuli." | 3.85 | Goniothalamin and Celecoxib Effects During Aging: Targeting Pro-Inflammatory Mediators in Chemoprevention of Prostatic Disorders. ( Cagnon, VHA; Kido, LA; Montico, F; Pilli, RA; Vendramini-Costa, DB, 2017) |
| " Our study was concerned with evaluating the effects of the selective COX2 inhibitor, celecoxib, on mammary tumorigenesis and aging in HER2/neu transgenic mice (24)." | 3.75 | [The effects of Celebrex on mammary tumorigenesis and aging in HER2/neu transgenic mice]. ( Anisimov, VN; Imianitov, EI; Piskunova, TS; Semenchenko, AV; Sokolenko, AP; Suspitsin, EN; Zabezhinskiĭ, MA, 2009) |
| "For diclofenac, area under the concentration-time curve over the dosage interval (AUC(tau)) was larger in young subjects (3." | 2.71 | Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib. ( Brenner, SS; Dilger, K; Herrlinger, C; Hofmann, U; Klotz, U; Marx, C; Mürdter, TE, 2003) |
| "Menopause is the permanent cessation of menstruation that results from depletion of ovarian germ cells and follicles." | 1.39 | Cyclooxygenase-1 inhibition prolongs postnatal ovarian follicle lifespan in mice. ( Cai, KQ; Smedberg, J; Smith, ER; Xu, XX; Yang, WL; Yeasky, T, 2013) |
| " We demonstrate that a reduction of cyclooxygenase 2 gene dosage rescued the ovarian aging phenotype of the Wv mice, whereas homozygous deletion was accompanied by a compensatory increase in ovarian cyclooxygenase 1 expression and prostaglandin E(2) synthesis." | 1.34 | A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice. ( Cai, KQ; Hamilton, TC; Klein-Szanto, A; Smedberg, JL; Smith, ER; Xu, XX; Yang, WL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, ER | 2 |
| Yang, WL | 2 |
| Yeasky, T | 1 |
| Smedberg, J | 1 |
| Cai, KQ | 2 |
| Xu, XX | 2 |
| Kido, LA | 1 |
| Montico, F | 1 |
| Vendramini-Costa, DB | 1 |
| Pilli, RA | 1 |
| Cagnon, VHA | 1 |
| Piskunova, TS | 1 |
| Suspitsin, EN | 1 |
| Sokolenko, AP | 1 |
| Zabezhinskiĭ, MA | 1 |
| Imianitov, EI | 1 |
| Semenchenko, AV | 1 |
| Anisimov, VN | 1 |
| Casolini, P | 1 |
| Catalani, A | 1 |
| Zuena, AR | 1 |
| Angelucci, L | 1 |
| Dilger, K | 2 |
| Herrlinger, C | 2 |
| Peters, J | 1 |
| Seyberth, HW | 1 |
| Schweer, H | 1 |
| Klotz, U | 2 |
| Brenner, SS | 1 |
| Mürdter, TE | 1 |
| Hofmann, U | 1 |
| Marx, C | 1 |
| Smedberg, JL | 1 |
| Klein-Szanto, A | 1 |
| Hamilton, TC | 1 |
| Zhao, H | 1 |
| Tanaka, T | 1 |
| Halicka, HD | 1 |
| Traganos, F | 1 |
| Zarebski, M | 1 |
| Dobrucki, J | 1 |
| Darzynkiewicz, Z | 1 |
| Lisse, J | 1 |
| Espinoza, L | 1 |
| Zhao, SZ | 1 |
| Dedhiya, SD | 1 |
| Osterhaus, JT | 1 |
3 trials available for celecoxib and Aging
| Article | Year |
|---|---|
Effects of celecoxib and diclofenac on blood pressure, renal function, and vasoactive prostanoids in young and elderly subjects.
Topics: Adult; Aged; Aging; Biomarkers; Blood Pressure; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi | 2002 |
Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib.
Topics: Adult; Aged; Aging; Alleles; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Celecoxib; Cross-Over | 2003 |
Functional status and health-related quality of life of elderly osteoarthritic patients treated with celecoxib.
Topics: Aged; Aged, 80 and over; Aging; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Female; H | 2001 |
6 other studies available for celecoxib and Aging
| Article | Year |
|---|---|
Cyclooxygenase-1 inhibition prolongs postnatal ovarian follicle lifespan in mice.
Topics: Aging; Animals; Celecoxib; Crosses, Genetic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 In | 2013 |
Goniothalamin and Celecoxib Effects During Aging: Targeting Pro-Inflammatory Mediators in Chemoprevention of Prostatic Disorders.
Topics: Aging; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Celecoxib; Chemoprevention; Drug Mo | 2017 |
[The effects of Celebrex on mammary tumorigenesis and aging in HER2/neu transgenic mice].
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Celecoxib; Cyclooxygenase | 2009 |
Inhibition of COX-2 reduces the age-dependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat.
Topics: Aging; Animals; Celecoxib; Cognition Disorders; Corticosterone; Cyclooxygenase 2; Cyclooxygenase 2 I | 2002 |
A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice.
Topics: Adenoma; Aging; Animals; Blotting, Western; Celecoxib; Cell Transformation, Neoplastic; Cyclooxygena | 2007 |
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Celecoxib; Cell | 2007 |