Page last updated: 2024-09-03

celastrol and Spinal Cord Injuries

celastrol has been researched along with Spinal Cord Injuries in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Feng, S; Li, C; Li, J; Liu, Q; Pang, Y; Shen, W; Wang, X; Wang, Z; Xu, Z1
Kaur, J; Mladinic, M; Nistri, A; Petrović, A; Tomljanović, I1
Dai, W; Li, C; Teng, H; Wang, B; Wang, J; Wang, X1
Fu, J; Li, Y; Lin, D; Qiu, Y; Ren, J; Yang, L; Zhu, C1

Other Studies

4 other study(ies) available for celastrol and Spinal Cord Injuries

ArticleYear
The discovery of the new mechanism: Celastrol improves spinal cord injury by increasing cAMP through VIP-ADCYAP1R1-GNAS pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Chromogranins; GTP-Binding Protein alpha Subunits, Gs; Pentacyclic Triterpenes; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Spinal Cord; Spinal Cord Injuries; Triterpenes

2023
Pharmacological induction of Heat Shock Protein 70 by celastrol protects motoneurons from excitotoxicity in rat spinal cord in vitro.
    The European journal of neuroscience, 2019, Volume: 49, Issue:2

    Topics: Animals; Animals, Newborn; Cell Line, Tumor; Cell Survival; Female; HSP70 Heat-Shock Proteins; Humans; Kainic Acid; Locomotion; Male; Motor Neurons; Neuroprotective Agents; Pentacyclic Triterpenes; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Triterpenes

2019
Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats.
    International immunopharmacology, 2019, Volume: 66

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Cells, Cultured; Disease Models, Animal; Female; Humans; Inflammation; Interleukin-18; Lipopolysaccharides; Microglia; Neuroprotective Agents; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Pentacyclic Triterpenes; Pyroptosis; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Triterpenes

2019
Celastrol attenuates inflammatory and neuropathic pain mediated by cannabinoid receptor type 2.
    International journal of molecular sciences, 2014, Aug-06, Volume: 15, Issue:8

    Topics: Analgesics; Animals; Camphanes; Carrageenan; Disease Models, Animal; Edema; Hyperalgesia; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred C57BL; Neuralgia; Pentacyclic Triterpenes; Pyrazoles; Receptor, Cannabinoid, CB2; Signal Transduction; Spinal Cord Injuries; Tripterygium; Triterpenes; Tumor Necrosis Factor-alpha

2014