celastrol has been researched along with Parkinson Disease in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, B; Qin, L; Su, Z; Wang, B; Zhang, C; Zhang, W; Zhao, M; Zheng, R | 1 |
| Cheung, AKL; Li, M; Ng, L; Su, C; Wang, X; Yang, C | 1 |
| Gong, N; Guo, L; Qu, B; Song, C; Sun, J; Zhu, S | 1 |
| Aouti, S; Jos, S; K N, K; Kamariah, N; Mythri, RB; Padavattan, S; Padmanabhan, B; Prasad, TK; R, K; Unni, S | 1 |
| Hao, J; Li, J | 1 |
| Choi, BS; Kim, H; Kim, S; Kim, SJ; Lee, HJ; Park, SE; Sapkota, K | 1 |
| Czarnecka, A; Domin, H; Jantas, D; Konieczny, J; Kuter, K; Lasoń, W; Lenda, T; Lorenc-Koci, E; Śmiałowska, M | 1 |
| Jantas, D; Konieczny, J; Kuśmierczyk, J; Lasoń, W; Lenda, T; Lorenc-Koci, E; Roman, A | 1 |
1 review(s) available for celastrol and Parkinson Disease
| Article | Year |
|---|---|
Treatment of Neurodegenerative Diseases with Bioactive Components of
Topics: Alzheimer Disease; Animals; Diterpenes; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Molecular Conformation; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Phenanthrenes; Phytotherapy; Tripterygium; Triterpenes | 2019 |
7 other study(ies) available for celastrol and Parkinson Disease
| Article | Year |
|---|---|
The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease.
Topics: Animals; Caspase 1; Disease Models, Animal; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Pentacyclic Triterpenes | 2021 |
Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic Cells.
Topics: Aged; alpha-Synuclein; Dendritic Cells; Humans; Neurodegenerative Diseases; Parkinson Disease; Pentacyclic Triterpenes; T-Lymphocytes | 2022 |
Celastrol attenuates 6-hydroxydopamine-induced neurotoxicity by regulating the miR-146a/PI3K/Akt/mTOR signaling pathways in differentiated rat pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Apoptosis; MicroRNAs; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Pentacyclic Triterpenes; Pheochromocytoma; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases | 2022 |
High-affinity binding of celastrol to monomeric α-synuclein mitigates in vitro aggregation.
Topics: alpha-Synuclein; Humans; Parkinson Disease; Pentacyclic Triterpenes | 2023 |
Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Humans; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; Pentacyclic Triterpenes; Rotenone; Triterpenes | 2014 |
Lack of neuroprotective effect of celastrol under conditions of proteasome inhibition by lactacystin in in vitro and in vivo studies: implications for Parkinson's disease.
Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Dopamine; Humans; Male; Mice; Neuroblastoma; Neurons; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Proteasome Inhibitors; Rats; Rats, Wistar; Substantia Nigra; Triterpenes | 2014 |
The extent of neurodegeneration and neuroprotection in two chemical in vitro models related to Parkinson's disease is critically dependent on cell culture conditions.
Topics: Acetylcysteine; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Humans; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Rotenone; Time Factors; Tretinoin; Triterpenes | 2013 |