celastrol has been researched along with Pancreatic Neoplasms in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, R; Sun, N; Tan, X; Tian, Q; Wu, X; Yan, M; Zeng, H; Zeng, X; Zhang, Z; Zhao, J; Zhu, X | 1 |
| Chen, X; Fu, Y; Gong, T; Han, X; Hu, Y; John Kao, W; Wang, M; Xu, Y; Zhang, ZR | 1 |
| Jiang, Z; Liu, Y; Tao, L; Zhao, Y | 1 |
| Ding, B; Prabhu, S; Thakkar, A; Wahid, MA; Wang, J; Wang, Z; Xie, C | 1 |
| Xiao, Y | 1 |
| Cartwright, JE; Chakravarthy, R; Clemens, MJ; Elia, A; Mudan, S; Perdios, N; Pirianov, G | 1 |
| Deeb, D; Gao, X; Gautam, SC; Liu, YB; Pindolia, K | 1 |
| Gao, S; Hao, J; Huang, H; Ji, W; Ren, H; Zhao, X | 1 |
| Deeb, D; Gao, X; Gautam, SC; Liu, Y; Pindolia, K | 1 |
| Aggarwal, BB; Chaturvedi, MM; Cho, SG; Kannappan, R; Liu, M; Prasad, S; Sung, B; Yadav, VR | 1 |
| Cheng, Z; Han, B; Jia, G; Jiang, H; Liu, J; Pan, S; Sun, B; Wang, Y; Zhou, H; Zhou, Y | 1 |
| Cao, X; Hamza, A; Sun, D; Wang, B; Yu, S; Zhan, CG; Zhang, T | 1 |
12 other study(ies) available for celastrol and Pancreatic Neoplasms
| Article | Year |
|---|---|
Celastrol-conjugated chitosan oligosaccharide for the treatment of pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Drug Liberation; Humans; Mice; Mice, Inbred BALB C; Oligosaccharides; Pancreatic Neoplasms; Particle Size; Pentacyclic Triterpenes; Solubility; Tumor Burden | 2022 |
Hierarchical assembly of hyaluronan coated albumin nanoparticles for pancreatic cancer chemoimmunotherapy.
Topics: Albumins; Animals; Cell Line, Tumor; Coated Materials, Biocompatible; Female; Humans; Hyaluronic Acid; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Nanoparticles; Neoplasm Proteins; Pancreatic Neoplasms; Pentacyclic Triterpenes; Triterpenes; Tryptophan; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2019 |
Pristimerin synergizes with gemcitabine through abrogating Chk1/53BP1-mediated DNA repair in pancreatic cancer cells.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Deoxycytidine; DNA Repair; Drug Synergism; Gemcitabine; Humans; Pancreatic Neoplasms; Pentacyclic Triterpenes; Tumor Suppressor p53-Binding Protein 1 | 2021 |
Triptolide and celastrol loaded silk fibroin nanoparticles show synergistic effect against human pancreatic cancer cells.
Topics: Cell Line, Tumor; Diterpenes; Drug Synergism; Epoxy Compounds; Fibroins; Humans; Nanoparticles; Pancreatic Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Triterpenes | 2017 |
Construction of a circRNA-miRNA-mRNA network to explore the pathogenesis and treatment of pancreatic ductal adenocarcinoma.
Topics: Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; HL-60 Cells; Humans; Imidazoles; Leupeptins; MicroRNAs; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Pentacyclic Triterpenes; Phosphorylation; Protein Interaction Maps; RNA, Circular; RNA, Messenger; Software; Treatment Outcome; Triterpenes | 2020 |
Role of the eIF4E binding protein 4E-BP1 in regulation of the sensitivity of human pancreatic cancer cells to TRAIL and celastrol-induced apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Pentacyclic Triterpenes; Phosphoproteins; Phosphorylation; Protein Binding; Protein Biosynthesis; Recombinant Proteins; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Triterpenes | 2013 |
Pristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-κB/mTOR signaling proteins and anti-apoptotic Bcl-2.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Mitochondria; NF-kappa B; Pancreatic Neoplasms; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes | 2014 |
Inhibition of autophagy strengthens celastrol-induced apoptosis in human pancreatic cancer in vitro and in vivo models.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Humans; Male; Mice; Pancreatic Neoplasms; Pentacyclic Triterpenes; Triterpenes; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Knock-In Techniques; Gene Knockdown Techniques; Humans; Pancreatic Neoplasms; Pentacyclic Triterpenes; Telomerase; Triterpenes | 2015 |
Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.
Topics: Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Neoplasm Invasiveness; NF-kappa B; Organ Specificity; Pancreatic Neoplasms; Pentacyclic Triterpenes; Protein Processing, Post-Translational; Receptors, CXCR4; Triterpenes; Tumor Necrosis Factor-alpha | 2010 |
Pristimerin causes G1 arrest, induces apoptosis, and enhances the chemosensitivity to gemcitabine in pancreatic cancer cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; DNA; Drug Synergism; G1 Phase Cell Cycle Checkpoints; Gemcitabine; Humans; NF-kappa B; Pancreatic Neoplasms; Pentacyclic Triterpenes; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Triterpenes | 2012 |
A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chaperonins; Enzyme Inhibitors; Homeodomain Proteins; HSP90 Heat-Shock Proteins; Humans; Mice; Models, Molecular; Molecular Structure; Pancreatic Neoplasms; Pentacyclic Triterpenes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Triterpenes; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2008 |