Page last updated: 2024-09-03

celastrol and Ovarian Neoplasms

celastrol has been researched along with Ovarian Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Bastow, KF; Chang, FR; Chen, IH; Cragg, GM; Hayashi, K; Lee, KH; Liaw, CC; Nakanishi, Y; Nozaki, H; Wu, YC1
Ding, F; Ding, J; Li, N; Li, X; Liu, R; Liu, W; Ning, Y; Ren, S; Wang, H; Zheng, H1
Lin, J; Liu, L; Liu, P; Long, X; Xu, X; Zhang, G; Zhao, Q1
Fang, H; Gao, Z; Jiang, Q; Li, C; Li, G; Li, N; Li, X; Nie, S; Ren, S; Wang, Z; Zhang, J1
Ding, J; Li, X; Nie, S; Ren, S; Wang, H; Wang, L; Zhang, L1
Arbab, AS; Deeb, D; Gao, X; Gautam, SC; Liu, Y1
Li, G; Li, J; Wang, S; Zhang, H1
Ding, WJ; He, QJ; Liu, XW; Lu, W; Xu, DQ; Yang, B; Zhao, YC; Zhu, H1

Other Studies

8 other study(ies) available for celastrol and Ovarian Neoplasms

ArticleYear
Antitumor agents. 228. five new agarofurans, Reissantins A-E, and cytotoxic principles from Reissantia buchananii.
    Journal of natural products, 2003, Volume: 66, Issue:11

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Celastraceae; Drug Screening Assays, Antitumor; Female; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plants, Medicinal; Sesquiterpenes; Tanzania; Tumor Cells, Cultured

2003
Synthesis and biological evaluation of celastrol derivatives as anti-ovarian cancer stem cell agents.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Molecular Structure; Neoplastic Stem Cells; Ovarian Neoplasms; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes; Wound Healing

2019
Comprehensive Analysis of Tripterine Anti-Ovarian Cancer Effects Using Weighted Gene Co-Expression Network Analysis and Molecular Docking.
    Medical science monitor : international medical journal of experimental and clinical research, 2022, Jan-13, Volume: 28

    Topics: Databases, Factual; Female; Gene Expression Profiling; Humans; Molecular Docking Simulation; Ovarian Neoplasms; Pentacyclic Triterpenes; Treatment Outcome

2022
Discovery of semisynthetic celastrol derivatives exhibiting potent anti-ovarian cancer stem cell activity and STAT3 inhibition.
    Chemico-biological interactions, 2022, Oct-01, Volume: 366

    Topics: Apoptosis; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Female; Humans; Neoplastic Stem Cells; Ovarian Neoplasms; Pentacyclic Triterpenes; STAT3 Transcription Factor

2022
Celastrol strongly inhibits proliferation, migration and cancer stem cell properties through suppression of Pin1 in ovarian cancer cells.
    European journal of pharmacology, 2019, Jan-05, Volume: 842

    Topics: Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; G2 Phase Cell Cycle Checkpoints; Humans; Kruppel-Like Factor 4; M Phase Cell Cycle Checkpoints; Neoplastic Stem Cells; NIMA-Interacting Peptidylprolyl Isomerase; Ovarian Neoplasms; Pentacyclic Triterpenes; Triterpenes

2019
Anticancer activity of pristimerin in ovarian carcinoma cells is mediated through the inhibition of prosurvival Akt/NF-κB/mTOR signaling.
    Journal of experimental therapeutics & oncology, 2014, Volume: 10, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mitochondria; NF-kappa B; Ovarian Neoplasms; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes

2014
Effects of celastrol on enhancing apoptosis of ovarian cancer cells via the downregulation of microRNA‑21 and the suppression of the PI3K/Akt‑NF‑κB signaling pathway in an in vitro model of ovarian carcinoma.
    Molecular medicine reports, 2016, Volume: 14, Issue:6

    Topics: Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; NF-kappa B; Ovarian Neoplasms; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Triterpenes

2016
Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L.
    Cancer letters, 2010, Nov-28, Volume: 297, Issue:2

    Topics: Animals; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Drug Synergism; Female; Gene Expression Regulation; Humans; Male; Mice; Mice, Nude; Ovarian Neoplasms; Pentacyclic Triterpenes; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Transfection; Triterpenes; Up-Regulation; Xenograft Model Antitumor Assays

2010