Page last updated: 2024-09-03

celastrol and Osteoarthritis

celastrol has been researched along with Osteoarthritis in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Chen, Q; Deng, M; Du, X; Huang, R; Yao, S1
Chen, H; Feng, K; Xu, C1
Liu, DD; Yang, JB; Zhang, BL; Zhou, K1
Dai, S; Lin, Z; Wang, H; Wang, M; Zhang, Y; Zhang, Z1
Gong, M; Ha, C; Lin, T; Wang, D; Wang, W; Wang, Y1
Chen, WP; Cheng, Y; Ding, QH; Wang, XH; Zhong, HM1

Other Studies

6 other study(ies) available for celastrol and Osteoarthritis

ArticleYear
A Novel Hypoxia Related Marker in Blood Link to Aid Diagnosis and Therapy in Osteoarthritis.
    Genes, 2022, 08-23, Volume: 13, Issue:9

    Topics: Amaryllidaceae Alkaloids; Biomarkers; Humans; Hydroxamic Acids; Hypoxia; NF-kappa B; Osteoarthritis; Pentacyclic Triterpenes; Phenanthridines; Tumor Suppressor Protein p53; Ubiquitins

2022
Chondro-protective effects of celastrol on osteoarthritis through autophagy activation and NF-κB signaling pathway inhibition.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2020, Volume: 69, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Autophagy; Cells, Cultured; Chondrocytes; Interleukin-1beta; Male; NF-kappa B; Osteoarthritis; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Signal Transduction; Triterpenes

2020
Celastrol ameliorates endoplasmic stress-mediated apoptosis of osteoarthritis via regulating ATF-6/CHOP signalling pathway.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:6

    Topics: Activating Transcription Factor 6; Animals; Apoptosis; Caspases; Cell Survival; Endoplasmic Reticulum Stress; Female; Osteoarthritis; Pentacyclic Triterpenes; Rats; Rats, Wistar; Transcription Factor CHOP; Triterpenes; Tunicamycin

2020
Comparative transcriptomics and network pharmacology analysis to identify the potential mechanism of celastrol against osteoarthritis.
    Clinical rheumatology, 2021, Volume: 40, Issue:10

    Topics: Drugs, Chinese Herbal; Humans; Molecular Docking Simulation; Osteoarthritis; Pentacyclic Triterpenes; Transcriptome

2021
Celastrol attenuates pain and cartilage damage via SDF-1/CXCR4 signalling pathway in osteoarthritis rats.
    The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cartilage, Articular; Chemokine CXCL12; Iodoacetic Acid; Male; Osteoarthritis; Pain; Pentacyclic Triterpenes; Rats; Receptors, CXCR4; RNA, Messenger; Signal Transduction; Triterpenes; Up-Regulation

2018
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
    European journal of pharmacology, 2013, May-15, Volume: 708, Issue:1-3

    Topics: Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; HSP90 Heat-Shock Proteins; Humans; Interleukin-1beta; Matrix Metalloproteinases; Nitric Oxide Synthase Type II; Osteoarthritis; Pentacyclic Triterpenes; Triterpenes

2013