celastrol has been researched along with Malignant Melanoma in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, Y; Jiang, W; Li, Z; Wang, R; Xie, C; Xie, S; Xie, X | 1 |
| An, L; Cong, X; Jia, Y; Li, J; Xiao, C; Yang, H; Zhang, P | 1 |
| Jiang, Y; Lazarovici, P; Li, S; Liao, R; Peng, T; Silva, M; Yan, F; Zheng, W | 1 |
| Chen, Y; Gao, J; Hu, M; Huang, L; Liu, Q; Liu, Y; Qiu, N; Shen, L; Shen, Y; Zhou, X | 1 |
| Pan, J; Zhang, B; Zhang, J | 1 |
| Chen, F; Hou, L; Huang, L; Liu, Q; Shen, L; Wang, D; Zhang, X | 1 |
| Chen, M; Doudican, N; Orlow, SJ; Osman, I; Rose, AE | 1 |
| Lee, JH; Lee, MK; Park, KH; Seo, KI; Tachibana, H; Won, YS; Yamada, K | 1 |
| Abbas, S; Bhoumik, A; Cosford, ND; Dahl, R; Krajewski, S; Ronai, ZA; Vasile, S | 1 |
9 other study(ies) available for celastrol and Malignant Melanoma
| Article | Year |
|---|---|
Pristimerin attenuates cell proliferation of uveal melanoma cells by inhibiting insulin-like growth factor-1 receptor and its downstream pathways.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Humans; Melanoma; Molecular Docking Simulation; Pentacyclic Triterpenes; Phosphorylation; Receptor, IGF Type 1; Signal Transduction; Triterpenes; Uveal Neoplasms | 2019 |
Celastrol Self-Stabilized Nanoparticles for Effective Treatment of Melanoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Delayed-Action Preparations; Dynamic Light Scattering; Hydrophobic and Hydrophilic Interactions; Male; Melanoma; Melanoma, Experimental; Mice, Inbred C57BL; Micelles; Microscopy, Electron, Transmission; Nanoparticles; Pentacyclic Triterpenes; Polyethylene Glycols; Polylysine; Triterpenes | 2020 |
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Nucleus; Forkhead Box Protein O3; Humans; Melanoma; Neoplasm Invasiveness; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Uveal Neoplasms | 2020 |
Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy.
Topics: Animals; B7-H1 Antigen; Humans; Immunotherapy; Melanoma; Mice; Pentacyclic Triterpenes; Tumor Microenvironment | 2021 |
Pristimerin effectively inhibits the malignant phenotypes of uveal melanoma cells by targeting NF‑κB pathway.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Melanoma; Molecular Targeted Therapy; Neoplastic Stem Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Pentacyclic Triterpenes; Signal Transduction; Transcription Factor RelA; Triterpenes; Tumor Necrosis Factor-alpha; Uveal Neoplasms; Vinblastine | 2017 |
Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Progression; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Immunosenescence; Immunotherapy; Melanoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitoxantrone; Nanoparticles; NIH 3T3 Cells; Pentacyclic Triterpenes; Skin Neoplasms; Triterpenes; Tumor Microenvironment | 2018 |
Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells.
Topics: Cell Death; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Gene Knockdown Techniques; Humans; I-kappa B Proteins; Inhibitory Concentration 50; Melanoma; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Pentacyclic Triterpenes; Phosphorylation; Proteasome Endopeptidase Complex; Protein Transport; RNA, Small Interfering; Temozolomide; Triterpenes; Tumor Necrosis Factor-alpha; Ubiquitinated Proteins | 2009 |
Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; Melanoma; Mitochondria; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Triterpenes | 2012 |
Preclinical studies of celastrol and acetyl isogambogic acid in melanoma.
Topics: Activating Transcription Factor 2; Animals; Cell Line, Tumor; Chromones; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Humans; MAP Kinase Kinase 4; Melanoma; Mice; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Small Molecule Libraries; Transcription, Genetic; Triterpenes | 2007 |