celastrol has been researched along with Leukemia, Myeloid, Acute in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coulibaly, A; Haas, A; Jakobs, A; Klempnauer, KH; Schmidt, TJ; Steinmann, S | 1 |
| Berdel, WE; Coulibaly, A; Dassé, E; Frampton, J; Jakobs, A; Jose, J; Klempnauer, KH; Müller-Tidow, C; Schlenke, P; Schmidt, TJ; Schomburg, C; Steinmann, S; Trentmann, A; Uttarkar, S | 1 |
| Ruan, X; Yu, X; Zhang, J; Zhao, Q | 1 |
| Abboud, R; Carroll, M; Corbett, C; Guzman, ML; Hassane, DC; Jordan, CT; Li, X; Liesveld, JL; Young, F | 1 |
4 other study(ies) available for celastrol and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression.
Topics: 3T3-L1 Cells; Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; CCAAT-Enhancer-Binding Proteins; Cell Line; Cell Proliferation; Chickens; Cysteine; Gene Expression; Humans; Leukemia, Myeloid, Acute; Mice; Myeloid Cells; p300-CBP Transcription Factors; Pentacyclic Triterpenes; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-myb; Quail; Triterpenes | 2018 |
Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction.
Topics: Animals; Cell Differentiation; Cell Proliferation; Chickens; Disease Models, Animal; E1A-Associated p300 Protein; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice, Inbred C57BL; Molecular Targeted Therapy; Myeloid Cells; Pentacyclic Triterpenes; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myb; Small Molecule Libraries; Triterpenes | 2016 |
Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) Leukemia.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Down-Regulation; Humans; Leukemia, Myeloid, Acute; Pentacyclic Triterpenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; RUNX1 Translocation Partner 1 Protein; Transcription Factors; Translocation, Genetic; Triterpenes | 2016 |
Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Death; Cysteine Proteinase Inhibitors; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Models, Genetic; Neoplastic Stem Cells; Oligonucleotide Array Sequence Analysis; Pentacyclic Triterpenes; Sesquiterpenes; Terpenes; Triterpenes; Xenograft Model Antitumor Assays | 2008 |