celastrol has been researched along with Glioma in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, Y; Fu, X; Lei, Y; Mou, Y; Ping, K; Wang, S; Wang, W; Zhang, Y; Zhao, J | 1 |
| Huang, Y; Liang, G; Sun, F; Sun, X; Zeng, L; Zhao, P; Zhu, S | 1 |
| Benedict, B; Hulleman, E; Kaspers, GJL; Koster, J; Meel, MH; Metselaar, DS; Waranecki, P | 1 |
| Gao, W; Liu, X; Song, Y; Wang, L; Wang, X; Zhao, P; Zhu, Y | 1 |
| Chi, G; Ge, P; Jin, Y; Liu, K; Lu, B; Luo, T; Luo, Y; Wang, C; Wang, Z; Zhao, H; Zheng, L; Zhou, Z; Zhu, D | 1 |
| Huang, YL; Zhou, YX | 1 |
| Ding, Y; Fu, S; Ge, P; Ji, X; Jin, X; Ling, F; Luo, Y; Meng, F; Wang, X | 1 |
| Alvarado, O; Blower, PE; Gout, PW; Huang, Y; Pham, AN; Ravula, R | 1 |
| Hang, T; Huang, Y; Liu, J; Wang, Z; Wu, Z; Xie, X; Xu, Q; Zhou, D; Zhou, Y; Zuo, J | 1 |
| Huang, YL; Sun, CF; Xu, QN; Ye, M; Zhou, D; Zhou, YX | 1 |
| Fan, Y; Huang, Y; Zhou, D; Zhou, Y | 1 |
11 other study(ies) available for celastrol and Glioma
| Article | Year |
|---|---|
Synthesis and biological evaluation of celastrol derivatives as potential anti-glioma agents by activating RIP1/RIP3/MLKL pathway to induce necroptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Cell Line, Tumor; Cell Proliferation; Glioma; Heterografts; Humans; Male; Mice; Necroptosis; Nuclear Pore Complex Proteins; Pentacyclic Triterpenes; Protein Kinases; Receptor-Interacting Protein Serine-Threonine Kinases; RNA-Binding Proteins; Signal Transduction; Structure-Activity Relationship; Wound Healing; Zebrafish | 2022 |
Brain-targeting biomimetic nanoparticles for codelivery of celastrol and LY2157299 for reversing glioma immunosuppression.
Topics: Albumins; Animals; Biomimetics; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioma; Immunosuppression Therapy; Mice; Nanoparticles; Pentacyclic Triterpenes; Pyrazoles; Quinolines; Transforming Growth Factor beta1 | 2022 |
Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin.
Topics: Adolescent; Animals; Carboplatin; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Cross-Linking Reagents; Disease Models, Animal; DNA Damage; Drug Resistance, Neoplasm; Fanconi Anemia Complementation Group D2 Protein; Female; Glioma; Humans; Male; Mice; Neoplasm Grading; Pentacyclic Triterpenes; Proteolysis; Triterpenes; Xenograft Model Antitumor Assays | 2019 |
Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.
Topics: Apoptosis; Autophagosomes; Autophagy; Cell Cycle Checkpoints; Cell Proliferation; Glioma; Humans; MAP Kinase Kinase 4; Microtubule-Associated Proteins; Pentacyclic Triterpenes; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes | 2019 |
Pristimerin triggers AIF-dependent programmed necrosis in glioma cells via activation of JNK.
Topics: Animals; Antineoplastic Agents; Apoptosis Inducing Factor; Cell Growth Processes; Cell Line, Tumor; Enzyme Activation; Glioma; Humans; MAP Kinase Kinase 4; Mice, Inbred BALB C; Mice, Nude; Necrosis; Pentacyclic Triterpenes; Rats; Triterpenes; Xenograft Model Antitumor Assays | 2016 |
Antiangiogenic effect of celastrol on the growth of human glioma: an in vitro and in vivo study.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chick Embryo; Chickens; Chorioallantoic Membrane; Female; Glioma; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Microvessels; Pentacyclic Triterpenes; Triterpenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2009 |
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Glioma; Microscopy, Electron, Transmission; Pentacyclic Triterpenes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Time Factors; Triterpenes | 2010 |
Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.
Topics: Amino Acid Transport System y+; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cystine; Drug Resistance, Neoplasm; Gene Expression Profiling; Glioma; Humans; Oligonucleotide Array Sequence Analysis; Pentacyclic Triterpenes; Pharmacogenetics; RNA, Small Interfering; Sulfasalazine; Triterpenes | 2010 |
Preparation, characterization, and assessment of the antiglioma effects of liposomal celastrol.
Topics: Animals; Antineoplastic Agents; Biological Availability; Brain Neoplasms; Cell Survival; Drug Compounding; Drug Delivery Systems; Female; Glioma; Humans; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Particle Size; Pentacyclic Triterpenes; Solubility; Surface Properties; Tissue Distribution; Triterpenes; Xenograft Model Antitumor Assays | 2012 |
[Several monomes from Tripterygium wilfordii inhibit proliferation of glioma cells in vitro].
Topics: Antineoplastic Agents; Cell Division; Diterpenes; Epoxy Compounds; Glioma; Humans; Inhibitory Concentration 50; Molecular Structure; Pentacyclic Triterpenes; Phenanthrenes; Plant Extracts; Tripterygium; Triterpenes; Tumor Cells, Cultured | 2002 |
Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Female; Glioma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Pentacyclic Triterpenes; Receptors, Vascular Endothelial Growth Factor; Transcription, Genetic; Triterpenes; Tumor Burden; Xenograft Model Antitumor Assays | 2008 |