Page last updated: 2024-09-03

celastrol and Diabetes Mellitus, Type 2

celastrol has been researched along with Diabetes Mellitus, Type 2 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Wu, M; Zhang, Y1
Chen, B; Hassan, M; He, Q; Li, X; Liu, X; Shen, Z; Song, Y; Wang, G; Wu, L; Wu, Q; Xiao, X; Zhang, H; Zhang, L; Zhao, Y; Zhou, D; Zhou, W1
Gu, J; Li, HF; Qin, L; Shi, YN; Zhang, CJ; Zhu, N1
Feng, Y; He, W; Li, X; Xu, S; Xu, W; Yang, H1
Chen, LM; Guan, Y; Han, LP; Li, CJ; Ma, ZJ; Sun, B; Xie, Y1
Leibel, R; Tortoriello, DV; Weisberg, S1
Choi, JW; Feng, X; Ibi, D; Lee, J; Liu, J; Mucka, P; Ozcan, U; Salazar Hernández, MA1

Reviews

2 review(s) available for celastrol and Diabetes Mellitus, Type 2

ArticleYear
Celastrol functions as an emerging manager of lipid metabolism: Mechanism and therapeutic potential.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 164

    Topics: Animals; Diabetes Mellitus, Type 2; Lipid Metabolism; Lipids; Mice; Pentacyclic Triterpenes; Triterpenes

2023
Celastrol in metabolic diseases: Progress and application prospects.
    Pharmacological research, 2021, Volume: 167

    Topics: Animals; Diabetes Mellitus, Type 2; Energy Metabolism; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Metabolic Diseases; Obesity; Pentacyclic Triterpenes; Tripterygium

2021

Other Studies

5 other study(ies) available for celastrol and Diabetes Mellitus, Type 2

ArticleYear
Combining bioinformatics, network pharmacology and artificial intelligence to predict the mechanism of celastrol in the treatment of type 2 diabetes.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: ADAMTS Proteins; Artificial Intelligence; Computational Biology; Diabetes Mellitus, Type 2; Gene Expression Profiling; Humans; Molecular Docking Simulation; Network Pharmacology; Transforming Growth Factor beta

2022
Celastrol targets the ChREBP-TXNIP axis to ameliorates type 2 diabetes mellitus.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 110

    Topics: Animals; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Type 2; Glucose; Hypoglycemic Agents; Mice; Molecular Docking Simulation; Pentacyclic Triterpenes; Thioredoxins

2023
Protective Effects of Celastrol on Diabetic Liver Injury via TLR4/MyD88/NF-κB Signaling Pathway in Type 2 Diabetic Rats.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Animals; Anti-Inflammatory Agents; Cytoprotection; Diabetes Mellitus, Type 2; Disease Models, Animal; Interleukin-1beta; Liver; Liver Diseases; Male; Myeloid Differentiation Factor 88; NF-kappa B; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Tumor Necrosis Factor-alpha

2016
Proteasome inhibitors, including curcumin, improve pancreatic β-cell function and insulin sensitivity in diabetic mice.
    Nutrition & diabetes, 2016, Apr-25, Volume: 6

    Topics: 3T3-L1 Cells; Animals; Body Composition; Cell Survival; Curcumin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Glycated Hemoglobin; Homeostasis; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Obesity; Oligopeptides; Pentacyclic Triterpenes; Polyphenols; Proteasome Inhibitors; Receptors, Leptin; Triterpenes

2016
Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice.
    Nature medicine, 2016, Volume: 22, Issue:9

    Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Liver; Fluorescent Antibody Technique; Glucose Tolerance Test; Hypothalamus; Immunohistochemistry; Leptin; Liver; Mice; Mice, Obese; Obesity; Pentacyclic Triterpenes; Real-Time Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Withanolides

2016