celastrol has been researched along with Colorectal Neoplasms in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 7 (46.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z; Han, Y; Jiang, M; Liu, M; Pan, S; Tang, Z; Wang, S; Wang, Y; Xu, N; Yin, K; Zhang, G; Zhu, H | 1 |
| Shang, F; Sun, H; Zhang, H; Zhao, X; Zheng, X; Zhu, J | 1 |
| Chen, H; Chen, L; Li, Q; Mao, X; Qi, H; Shi, H; Shi, X; Wang, T; Wang, X; Wu, Z; Zhang, W; Zhong, M | 1 |
| Chen, L; Hu, C; Hu, G; Liu, M; Ma, K; Wang, S; Xu, N; Zhou, C; Zhu, H | 1 |
| Chen, G; Ding, C; Ding, X; Gao, J; Jiang, D; Li, Y; Luo, C; Xu, H; Xu, Y; Zhang, A; Zhang, H; Zhao, H; Zhao, Z; Zhou, H | 1 |
| Bi, Y; Jia, J; Liu, Y; Ren, Z; Tan, Y; Yu, M; Yu, X; Zhang, Q; Zhao, Q; Zhong, J | 1 |
| Bi, Y; Guo, J; Guo, Y; Liu, Y; Pan, L; Tan, Y; Yu, X; Zhao, Q; Zhong, J | 1 |
| Barker, EC; Choi, SH; Kim, BG; Letterio, JJ; Tochtrop, GP; Yoon, JH | 1 |
| Hassan, HM; Jiang, ZZ; Yousef, BA; Zhang, LY | 1 |
| Bufu, T; Di, X; Gege, L; Ling, W; Xi, C; Yilin, Z | 1 |
| Dong, YF; Ji-Kuai, C; Jiang-Bo, Z; Wen-Jun, C; Xiao-Fang, Z; Xiao-Pei, H; Xue, W; Ya-Min, P; Yan, L | 1 |
| Gao, Y; Huo, X; Li, HJ; Pang, L; Qian, SY; Yang, J; Zhou, S | 1 |
| Guerram, M; Hamdi, AM; Hassan, HM; Jiang, ZZ; Yousef, BA; Zhang, LY | 1 |
| Guerram, M; Hamdi, AM; Hassan, HM; Jiang, ZZ; Wang, B; Yousef, BA; Zhang, LY | 1 |
| Ding, WJ; He, QJ; Liu, XW; Lu, W; Xu, DQ; Yang, B; Zhao, YC; Zhu, H | 1 |
15 other study(ies) available for celastrol and Colorectal Neoplasms
| Article | Year |
|---|---|
Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; Hypothalamus; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oxytocin; Pentacyclic Triterpenes | 2021 |
Celastrol Inhibits the Proliferation and Induces Apoptosis of Colorectal Cancer Cells via Downregulating NF-κB/COX-2 Signaling Pathways.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; G1 Phase Cell Cycle Checkpoints; Humans; NF-kappa B; Pentacyclic Triterpenes; Signal Transduction; Triterpenes | 2022 |
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Mice; Pentacyclic Triterpenes | 2022 |
Celastrol acts as a new histone deacetylase inhibitor to inhibit colorectal cancer cell growth via regulating macrophage polarity.
Topics: Animals; Cell Polarity; Cell Transformation, Neoplastic; Colorectal Neoplasms; Histone Deacetylase Inhibitors; Macrophages; Mice; Pentacyclic Triterpenes; Tumor Microenvironment | 2023 |
Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Topics: Animals; Colorectal Neoplasms; Humans; Mice; Mice, Nude; Pentacyclic Triterpenes; Triterpenes | 2023 |
Pristimerin suppresses colorectal cancer through inhibiting inflammatory responses and Wnt/β-catenin signaling.
Topics: Animals; Antineoplastic Agents; Colorectal Neoplasms; Disease Models, Animal; Female; Glycogen Synthase Kinase 3 beta; HCT116 Cells; HT29 Cells; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Pentacyclic Triterpenes; Triterpenes; Wnt Signaling Pathway | 2020 |
Effect of pristimerin on apoptosis through activation of ROS/ endoplasmic reticulum (ER) stress-mediated noxa in colorectal cancer.
Topics: Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Endoribonucleases; Female; Humans; JNK Mitogen-Activated Protein Kinases; Mice, Inbred BALB C; Pentacyclic Triterpenes; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; TNF Receptor-Associated Factor 2; Triterpenes; Xenograft Model Antitumor Assays | 2021 |
Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation.
Topics: Animals; Anti-Inflammatory Agents; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dietary Supplements; Male; Mice; Mice, Inbred C57BL; Pentacyclic Triterpenes; Triterpenes | 2018 |
Pristimerin exhibits in vitro and in vivo anticancer activities through inhibition of nuclear factor-кB signaling pathway in colorectal cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; HCT116 Cells; Humans; Lipopolysaccharides; Mice, Inbred BALB C; NF-kappa B; Pentacyclic Triterpenes; Phosphorylation; Signal Transduction; Triterpenes; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2018 |
Celastrol inhibits colorectal cancer cell proliferation and migration through suppression of MMP3 and MMP7 by the PI3K/AKT signaling pathway.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; HCT116 Cells; Humans; Matrix Metalloproteinase 3; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes; Up-Regulation | 2018 |
Systematic identification of Celastrol-binding proteins reveals that Shoc2 is inhibited by Celastrol.
Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Pentacyclic Triterpenes; Protein Array Analysis; Protein Binding; RNA, Small Interfering; Triterpenes; Xenograft Model Antitumor Assays | 2018 |
Celastrol suppresses nitric oxide synthases and the angiogenesis pathway in colorectal cancer.
Topics: Cell Proliferation; Colorectal Neoplasms; Humans; Nitric Oxide Synthase; Pentacyclic Triterpenes; Signal Transduction; Tripterygium; Triterpenes | 2019 |
Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Drug Screening Assays, Antitumor; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Membrane Potential, Mitochondrial; Neoplasm Proteins; Pentacyclic Triterpenes; Signal Transduction; Triterpenes | 2016 |
Pristimerin inhibits proliferation, migration and invasion, and induces apoptosis in HCT-116 colorectal cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Female; HCT116 Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Pentacyclic Triterpenes; Reactive Oxygen Species; Triterpenes; Xenograft Model Antitumor Assays | 2016 |
Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L.
Topics: Animals; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Drug Synergism; Female; Gene Expression Regulation; Humans; Male; Mice; Mice, Nude; Ovarian Neoplasms; Pentacyclic Triterpenes; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Transfection; Triterpenes; Up-Regulation; Xenograft Model Antitumor Assays | 2010 |