Page last updated: 2024-09-03

celastrol and Cirrhosis

celastrol has been researched along with Cirrhosis in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's8 (80.00)2.80

Authors

AuthorsStudies
Lin, Y; Tang, XL; Tang, YW; Wan, F; Yang, RC; Zhang, HQ1
Ahmed Abdi, B; Arora, R; Biernaskie, J; Carter, DE; Chitturi, P; Leask, A; Nguyen, J; Sinha, S; Stratton, RJ; Xu, S1
Chen, W; Fan, J; He, Y; Ren, M; Wang, H1
Chen, DY; Chiu, TM; Chuang, PH; Hsu, TC; Kuo, CW; Lin, JW; Liu, CM; Tzang, BS; Tzang, CC1
Chen, S; He, J; Jiang, X; Liu, M; Lu, W; Ye, X; Yi, C; Zhang, Q1
Feng, Y; Han, M; He, J; Huang, C; Huang, H; Huang, Y; Li, R; Li, Y; Liu, Q; Ma, L; Mo, L; Tang, Q; Wu, T; Zhang, G; Zhang, J; Zhang, Z; Zhao, Y; Zhou, J1
Faust, I; Fischer, B; Hendig, D; Kleine, A; Knabbe, C; Kuhn, J; Ly, TD; Schmidt, V1
Chen, Q; Chen, X; Lin, C; Liu, T; Ren, L; Shan, W; Yang, Q; Zhang, H; Zhang, L; Zhang, X; Zheng, H1
Cao, X; He, QH; Li, GQ; Li, SJ; Li, Y; Tang, M; Xu, GL; Zhang, K; Zhang, KQ; Zheng, QY1
Cheng, M; Song, Y; Tu, L; Wang, L; Wu, G; Zhang, C; Zhang, L1

Other Studies

10 other study(ies) available for celastrol and Cirrhosis

ArticleYear
Celastrol attenuates renal injury in 5/6 nephrectomized rats via inhibiting epithelial-mesenchymal transition and transforming growth factor-β1/Smad3 pathway.
    Experimental biology and medicine (Maywood, N.J.), 2022, Volume: 247, Issue:21

    Topics: Animals; Cholesterol; Creatinine; Epithelial-Mesenchymal Transition; Fibrosis; Kidney; Mice; Nephrectomy; Pentacyclic Triterpenes; Rats; Serum Albumin; Smad3 Protein; Transforming Growth Factor beta1; Triglycerides

2022
    Annals of the rheumatic diseases, 2023, Volume: 82, Issue:9

    Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Mice; Scleroderma, Systemic; Skin; Skin Diseases; Transcription Factors; Tripterygium

2023
Celastrol relieves myocardial infarction-induced cardiac fibrosis by inhibiting NLRP3 inflammasomes in rats.
    International immunopharmacology, 2023, Volume: 121

    Topics: Animals; Fibrosis; Inflammasomes; Interleukin-18; Male; Molecular Docking Simulation; Myocardial Infarction; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley

2023
Effect of the Functional VP1 Unique Region of Human Parvovirus B19 in Causing Skin Fibrosis of Systemic Sclerosis.
    International journal of molecular sciences, 2023, Oct-18, Volume: 24, Issue:20

    Topics: Animals; Capsid Proteins; Fibrosis; Humans; Interleukin-6; Matrix Metalloproteinase 9; Mice; Parvoviridae Infections; Parvovirus B19, Human; Scleroderma, Systemic; Tumor Necrosis Factor-alpha; Viral Proteins

2023
Celastrol is a novel selective agonist of cannabinoid receptor 2 with anti-inflammatory and anti-fibrotic activity in a mouse model of systemic sclerosis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 67

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrestin; Bleomycin; Calcium; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrosis; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Pentacyclic Triterpenes; RAW 264.7 Cells; Receptor, Cannabinoid, CB2; Scleroderma, Systemic; Triterpenes

2020
Targeted delivery of celastrol to renal interstitial myofibroblasts using fibronectin-binding liposomes attenuates renal fibrosis and reduces systemic toxicity.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 04-10, Volume: 320

    Topics: Animals; Fibroblasts; Fibronectins; Fibrosis; Kidney; Liposomes; Mice; Myofibroblasts; Pentacyclic Triterpenes

2020
Identification of Putative Non-Substrate-Based XT-I Inhibitors by Natural Product Library Screening.
    Biomolecules, 2020, 10-21, Volume: 10, Issue:10

    Topics: Amphotericin B; Biological Products; Cells, Cultured; Enzyme Inhibitors; Extracellular Matrix; Fibrosis; Humans; MicroRNAs; Molecular Docking Simulation; Myofibroblasts; Pentacyclic Triterpenes; Pentosyltransferases; Signal Transduction; Tandem Mass Spectrometry; Transforming Growth Factor beta1; UDP Xylose-Protein Xylosyltransferase

2020
Tubule-specific protein nanocages potentiate targeted renal fibrosis therapy.
    Journal of nanobiotechnology, 2021, May-26, Volume: 19, Issue:1

    Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Epithelial Cells; Fibrosis; Kidney; Kidney Tubules; Male; Mice; Mice, Inbred BALB C; Pentacyclic Triterpenes; Rats; Rats, Sprague-Dawley; Ureteral Obstruction

2021
Celastrol alleviates renal fibrosis by upregulating cannabinoid receptor 2 expression.
    Cell death & disease, 2018, 05-22, Volume: 9, Issue:6

    Topics: Animals; Camphanes; Disease Models, Animal; Fibrosis; Humans; Inflammation; Kidney; Kidney Diseases; Male; Mice, Inbred BALB C; Pentacyclic Triterpenes; Pyrazoles; Receptor, Cannabinoid, CB2; Signal Transduction; Smad3 Protein; Triterpenes; Up-Regulation; Ureteral Obstruction

2018
Celastrol-Induced Suppression of the MiR-21/ERK Signalling Pathway Attenuates Cardiac Fibrosis and Dysfunction.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:5

    Topics: Actins; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cell Survival; Collagen; Disease Models, Animal; Down-Regulation; Fibrosis; Heart Ventricles; Male; MAP Kinase Signaling System; Mice; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Natriuretic Peptide, Brain; Pentacyclic Triterpenes; Phosphorylation; Transforming Growth Factor beta1; Triterpenes; Up-Regulation

2016