Page last updated: 2024-09-03

celastrol and Chemical and Drug Induced Liver Injury

celastrol has been researched along with Chemical and Drug Induced Liver Injury in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's5 (62.50)2.80

Authors

AuthorsStudies
Cheng, Y; Dai, M; Li, F; Ma, X; Peng, W; Wang, C; Zhang, T; Zhao, Q1
Chen, X; Li, M; Liu, C; Luo, Q; Qiu, F; Sun, X; Tao, Y1
Chen, X; Cheng, W; Ding, X; Liu, X; Wan, Y; Wu, L; Yang, B; Yang, N; Yu, S; Yu, X; Zhang, G; Zheng, J1
Huang, J; Lai, W; Li, G; Liao, J; Liu, W; Wang, F; Xie, D; Xu, R; Zhang, R; Zhang, Z; Zhou, M1
Gonzalez, FJ; Huang, JF; Li, F; Tang, P; Xiao, XR; Zhang, T; Zhao, Q; Zhu, WF1
Alitongbieke, G; Cai, L; Chen, H; Chen, X; Chong, S; Diaz-Meco, MT; Fang, H; Hu, M; Jiang, F; Lin, X; Liu, J; Luo, Q; Moscat, J; Su, Y; Wang, Z; Xie, L; Xu, C; Yang, S; Ye, X; Zhang, D; Zhang, F; Zhang, XK; Zhou, H; Zhou, Y1
Abdelaziz, HA; Gameil, NM; Hamed, MF; Shaker, ME1
Alpertunga, B; Jannuzzi, AT; Kara, M1

Other Studies

8 other study(ies) available for celastrol and Chemical and Drug Induced Liver Injury

ArticleYear
Metabolomics reveals the role of PPARĪ± in Tripterygium Wilfordii-induced liver injury.
    Journal of ethnopharmacology, 2022, May-10, Volume: 289

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diterpenes; Epoxy Compounds; Male; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentacyclic Triterpenes; Phenanthrenes; Plant Extracts; PPAR alpha; Tablets; Tripterygium

2022
Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns.
    BMC complementary medicine and therapies, 2023, Jan-10, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Mice; RNA, Messenger; Tripterygium; Tumor Necrosis Factor-alpha; Zebrafish

2023
Celastrol-loaded biomimetic nanodrug ameliorates APAP-induced liver injury through modulating macrophage polarization.
    Journal of molecular medicine (Berlin, Germany), 2023, Volume: 101, Issue:6

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Biomimetics; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Humans; Liver; Liver Diseases; Macrophages; Mice; Mice, Inbred C57BL; Nanoparticles

2023
A celastrol-based nanodrug with reduced hepatotoxicity for primary and metastatic cancer treatment.
    EBioMedicine, 2023, Volume: 94

    Topics: Apoptosis; Chemical and Drug Induced Liver Injury; Heparin, Low-Molecular-Weight; Humans; Nanoparticles; Neoplasms; P-Selectin; Phosphatidylinositol 3-Kinases; Triterpenes

2023
Celastrol ameliorates acute liver injury through modulation of PPARĪ±.
    Biochemical pharmacology, 2020, Volume: 178

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Male; Mice; Mice, 129 Strain; Mice, Knockout; Pentacyclic Triterpenes; Plant Roots; PPAR alpha; Tripterygium; Triterpenes

2020
Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy.
    Molecular cell, 2017, Apr-06, Volume: 66, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Autophagy; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Genotype; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Ligands; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Mitophagy; Nuclear Receptor Subfamily 4, Group A, Member 1; Pentacyclic Triterpenes; Phenotype; Protein Binding; Protein Interaction Domains and Motifs; RNA Interference; Sequestosome-1 Protein; Signal Transduction; TNF Receptor-Associated Factor 2; Transfection; Triterpenes; Ubiquitination

2017
Repression of acetaminophen-induced hepatotoxicity by a combination of celastrol and brilliant blue G.
    Toxicology letters, 2017, Jun-05, Volume: 275

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Cytokines; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Liver; Liver Function Tests; Male; Mice, Inbred BALB C; Oxidative Stress; Pentacyclic Triterpenes; Rosaniline Dyes; Triterpenes

2017
Celastrol ameliorates acetaminophen-induced oxidative stress and cytotoxicity in HepG2 cells.
    Human & experimental toxicology, 2018, Volume: 37, Issue:7

    Topics: Acetaminophen; Antioxidants; Catalase; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hep G2 Cells; Humans; Malondialdehyde; Oxidative Stress; Pentacyclic Triterpenes; Protein Carbonylation; Superoxide Dismutase; Triterpenes

2018