Page last updated: 2024-09-03

celastrol and Cancer of Pancreas

celastrol has been researched along with Cancer of Pancreas in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's8 (66.67)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Li, R; Sun, N; Tan, X; Tian, Q; Wu, X; Yan, M; Zeng, H; Zeng, X; Zhang, Z; Zhao, J; Zhu, X1
Chen, X; Fu, Y; Gong, T; Han, X; Hu, Y; John Kao, W; Wang, M; Xu, Y; Zhang, ZR1
Jiang, Z; Liu, Y; Tao, L; Zhao, Y1
Ding, B; Prabhu, S; Thakkar, A; Wahid, MA; Wang, J; Wang, Z; Xie, C1
Xiao, Y1
Cartwright, JE; Chakravarthy, R; Clemens, MJ; Elia, A; Mudan, S; Perdios, N; Pirianov, G1
Deeb, D; Gao, X; Gautam, SC; Liu, YB; Pindolia, K1
Gao, S; Hao, J; Huang, H; Ji, W; Ren, H; Zhao, X1
Deeb, D; Gao, X; Gautam, SC; Liu, Y; Pindolia, K1
Aggarwal, BB; Chaturvedi, MM; Cho, SG; Kannappan, R; Liu, M; Prasad, S; Sung, B; Yadav, VR1
Cheng, Z; Han, B; Jia, G; Jiang, H; Liu, J; Pan, S; Sun, B; Wang, Y; Zhou, H; Zhou, Y1
Cao, X; Hamza, A; Sun, D; Wang, B; Yu, S; Zhan, CG; Zhang, T1

Other Studies

12 other study(ies) available for celastrol and Cancer of Pancreas

ArticleYear
Celastrol-conjugated chitosan oligosaccharide for the treatment of pancreatic cancer.
    Drug delivery, 2022, Volume: 29, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Drug Liberation; Humans; Mice; Mice, Inbred BALB C; Oligosaccharides; Pancreatic Neoplasms; Particle Size; Pentacyclic Triterpenes; Solubility; Tumor Burden

2022
Hierarchical assembly of hyaluronan coated albumin nanoparticles for pancreatic cancer chemoimmunotherapy.
    Nanoscale, 2019, Sep-21, Volume: 11, Issue:35

    Topics: Albumins; Animals; Cell Line, Tumor; Coated Materials, Biocompatible; Female; Humans; Hyaluronic Acid; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Nanoparticles; Neoplasm Proteins; Pancreatic Neoplasms; Pentacyclic Triterpenes; Triterpenes; Tryptophan; Tumor Microenvironment; Xenograft Model Antitumor Assays

2019
Pristimerin synergizes with gemcitabine through abrogating Chk1/53BP1-mediated DNA repair in pancreatic cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 147

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Deoxycytidine; DNA Repair; Drug Synergism; Gemcitabine; Humans; Pancreatic Neoplasms; Pentacyclic Triterpenes; Tumor Suppressor p53-Binding Protein 1

2021
Triptolide and celastrol loaded silk fibroin nanoparticles show synergistic effect against human pancreatic cancer cells.
    Nanoscale, 2017, Aug-17, Volume: 9, Issue:32

    Topics: Cell Line, Tumor; Diterpenes; Drug Synergism; Epoxy Compounds; Fibroins; Humans; Nanoparticles; Pancreatic Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Triterpenes

2017
Construction of a circRNA-miRNA-mRNA network to explore the pathogenesis and treatment of pancreatic ductal adenocarcinoma.
    Journal of cellular biochemistry, 2020, Volume: 121, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; HL-60 Cells; Humans; Imidazoles; Leupeptins; MicroRNAs; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Pentacyclic Triterpenes; Phosphorylation; Protein Interaction Maps; RNA, Circular; RNA, Messenger; Software; Treatment Outcome; Triterpenes

2020
Role of the eIF4E binding protein 4E-BP1 in regulation of the sensitivity of human pancreatic cancer cells to TRAIL and celastrol-induced apoptosis.
    Biology of the cell, 2013, Volume: 105, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Pentacyclic Triterpenes; Phosphoproteins; Phosphorylation; Protein Binding; Protein Biosynthesis; Recombinant Proteins; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Triterpenes

2013
Pristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-κB/mTOR signaling proteins and anti-apoptotic Bcl-2.
    International journal of oncology, 2014, Volume: 44, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Mitochondria; NF-kappa B; Pancreatic Neoplasms; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes

2014
Inhibition of autophagy strengthens celastrol-induced apoptosis in human pancreatic cancer in vitro and in vivo models.
    Current molecular medicine, 2014, Volume: 14, Issue:4

    Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Humans; Male; Mice; Pancreatic Neoplasms; Pentacyclic Triterpenes; Triterpenes; Tumor Burden; Xenograft Model Antitumor Assays

2014
Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.
    Oncology reports, 2015, Volume: 34, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Knock-In Techniques; Gene Knockdown Techniques; Humans; Pancreatic Neoplasms; Pentacyclic Triterpenes; Telomerase; Triterpenes

2015
Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.
    Journal of molecular medicine (Berlin, Germany), 2010, Volume: 88, Issue:12

    Topics: Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Neoplasm Invasiveness; NF-kappa B; Organ Specificity; Pancreatic Neoplasms; Pentacyclic Triterpenes; Protein Processing, Post-Translational; Receptors, CXCR4; Triterpenes; Tumor Necrosis Factor-alpha

2010
Pristimerin causes G1 arrest, induces apoptosis, and enhances the chemosensitivity to gemcitabine in pancreatic cancer cells.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; DNA; Drug Synergism; G1 Phase Cell Cycle Checkpoints; Gemcitabine; Humans; NF-kappa B; Pancreatic Neoplasms; Pentacyclic Triterpenes; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Triterpenes

2012
A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chaperonins; Enzyme Inhibitors; Homeodomain Proteins; HSP90 Heat-Shock Proteins; Humans; Mice; Models, Molecular; Molecular Structure; Pancreatic Neoplasms; Pentacyclic Triterpenes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Triterpenes; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2008