Page last updated: 2024-09-03

celastrol and Body Weight

celastrol has been researched along with Body Weight in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (81.82)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Afrin, S; Cao, J; Chau, D; Cheng, B; Dong, Y; Gao, Y; He, Z; Hu, L; Huang, Y; Hwang, ES; Kabahizi, A; Lieu, L; Okolo, J; Wallace, B; Williams, KW; Yao, T1
Cifre, M; Oliver, P; Palou, A; Reynés, B1
Auen, T; Choi, JW; Copps, KD; Faruk, F; Feng, X; Guan, D; Ozcan, U; Salazar-Hernandez, MA1
Guo, L; Li, J; Li, Q; Luo, X; Wang, Y; Wu, G; Xi, J1
Greenhill, C1
Baur, JA; Chellappa, K; Naidoo, N; Perron, IJ1
Berglund, ED; Cui, H; Davis, KC; Grobe, JL; Jiang, J; Morgan, DA; Rahmouni, K; Saito, K; Singh, U; Toth, BA1
Bekerman, V; Caprioli, J; Gu, L; Kwong, JM; Kyung, H; Piri, N; Yadegari, D1
Ampong, B; Benny Klimek, ME; Dillingham, BC; Gallardo, E; Gernapudi, R; Gordish-Dressman, H; Jordan, S; Nagaraju, K; Rayavarapu, S; Spurney, CF; Van der Meulen, JH1
Cai, F; Liu, L; Liu, X; Yang, A; Zhang, Y1
Choi, JW; Feng, X; Ibi, D; Lee, J; Liu, J; Mucka, P; Ozcan, U; Salazar Hernández, MA1

Other Studies

11 other study(ies) available for celastrol and Body Weight

ArticleYear
PERK in POMC neurons connects celastrol with metabolism.
    JCI insight, 2021, 09-22, Volume: 6, Issue:18

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Diet, High-Fat; Eating; eIF-2 Kinase; Endoplasmic Reticulum Stress; Energy Metabolism; Glucose; Insulin Resistance; Leptin; Male; Mice; Mice, Knockout; Neurons; Obesity; Pentacyclic Triterpenes; Pro-Opiomelanocortin

2021
Perinatal Treatment with Leptin, but Not Celastrol, Protects from Metabolically Obese, Normal-Weight Phenotype in Rats.
    Nutrients, 2022, May-29, Volume: 14, Issue:11

    Topics: Animals; Body Weight; Diet, High-Fat; Dietary Fats; Female; Insulin; Leptin; Obesity; Pentacyclic Triterpenes; Phenotype; Pregnancy; Rats

2022
Lipocalin 2 Does Not Play A Role in Celastrol-Mediated Reduction in Food Intake and Body Weight.
    Scientific reports, 2019, 09-05, Volume: 9, Issue:1

    Topics: Animals; Anti-Obesity Agents; Body Weight; Eating; Female; Gene Expression; Lipocalin-2; Male; Mice, Inbred C57BL; Obesity; Pentacyclic Triterpenes; Triterpenes; Weight Loss

2019
Celastrol inhibits glucocorticoid‑induced osteoporosis in rat via the PI3K/AKT and Wnt signaling pathways.
    Molecular medicine reports, 2018, Volume: 18, Issue:5

    Topics: Animals; Body Weight; Calcium; Cell Differentiation; Collagen Type I; Disease Models, Animal; Gene Expression Regulation; Glucocorticoids; Humans; Male; Oncogene Protein v-akt; Osteocalcin; Osteoporosis; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Rats; Tartrate-Resistant Acid Phosphatase; Triterpenes; Wnt Signaling Pathway

2018
Mechanism revealed for celastrol's effects on weight.
    Nature reviews. Endocrinology, 2018, Volume: 14, Issue:11

    Topics: Body Weight; Humans; Pentacyclic Triterpenes; Triterpenes; Uncoupling Protein 1; Weight Loss

2018
The leptin sensitizer celastrol reduces age-associated obesity and modulates behavioral rhythms.
    Aging cell, 2019, Volume: 18, Issue:3

    Topics: Aging; Animals; Behavior, Animal; Body Weight; Circadian Rhythm; Eating; Energy Metabolism; Glucose Tolerance Test; Injections, Intraperitoneal; Leptin; Male; Mice; Obesity; Pentacyclic Triterpenes; Triterpenes; Weight Loss

2019
Celastrol Reduces Obesity in MC4R Deficiency and Stimulates Sympathetic Nerve Activity Affecting Metabolic and Cardiovascular Functions.
    Diabetes, 2019, Volume: 68, Issue:6

    Topics: Adipose Tissue, Brown; Animals; Arterial Pressure; Basal Metabolism; Body Weight; Cytokines; Diet, High-Fat; Disease Models, Animal; Eating; Endoplasmic Reticulum Stress; Energy Metabolism; Inflammation; Kidney; Mice; Mice, Knockout; Obesity; Pentacyclic Triterpenes; Receptor, Melanocortin, Type 4; Receptors, Leptin; Sympathetic Nervous System; Triterpenes; Weight Loss

2019
Celastrol supports survival of retinal ganglion cells injured by optic nerve crush.
    Brain research, 2015, Jun-03, Volume: 1609

    Topics: Animals; Body Weight; Cell Count; Cell Survival; Disease Models, Animal; DNA-Binding Proteins; Down-Regulation; Heat Shock Transcription Factors; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); HSP70 Heat-Shock Proteins; Nerve Crush; Neuroprotective Agents; Optic Nerve; Optic Nerve Injuries; Pentacyclic Triterpenes; Rats; Retinal Ganglion Cells; Transcription Factors; Triterpenes; Tumor Necrosis Factor-alpha

2015
Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J mice.
    Journal of the neurological sciences, 2015, Sep-15, Volume: 356, Issue:1-2

    Topics: Analysis of Variance; Animals; Body Weight; Cytokines; Disease Models, Animal; Dysferlin; Echocardiography; Female; Gene Expression Regulation; In Vitro Techniques; Inflammation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle Strength; Muscle, Skeletal; Muscular Dystrophies, Limb-Girdle; Pentacyclic Triterpenes; Triterpenes

2015
Celastrol, an NF-κB inhibitor, ameliorates hypercalciuria and articular cartilage lesions in a mouse model of secondary osteoporosis.
    Journal of pharmacological sciences, 2016, Volume: 130, Issue:4

    Topics: Adipose Tissue; Animals; Body Weight; Cartilage, Articular; Disease Models, Animal; Disease Progression; Hypercalciuria; Leptin; Lipid Metabolism; Male; Mice, Inbred C57BL; Molecular Targeted Therapy; NF-kappa B; Osteoporosis; Parathyroid Hormone; Pentacyclic Triterpenes; Triterpenes

2016
Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice.
    Nature medicine, 2016, Volume: 22, Issue:9

    Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Liver; Fluorescent Antibody Technique; Glucose Tolerance Test; Hypothalamus; Immunohistochemistry; Leptin; Liver; Mice; Mice, Obese; Obesity; Pentacyclic Triterpenes; Real-Time Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Withanolides

2016